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Job DescriptionP45524
Confidence99.91%DateThu Jan 5 12:02:54 GMT 2012
Rank111Aligned Residues243
% Identity14%Templatec2g5tA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3940.........50.........60...... ...70.........80..... ....90.........100.........110...
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Query Sequence  RQVKFTPYWQRLELPDGDFVDLAWSENP. . AQAQHKPRLVVFHGLEGSL. . . NSPYAHGLVEAAQKRGWLGVVMHFRGCS
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Template Sequence  QNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSG
Template Known Secondary structure  TTB


TT
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   505....510.........520.........530.........540.........550.........560.........570.........580....
 
   114.. ...120.........130.........140. ........150.........160.........170.........180.......
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Query Sequence  GEP. . . . NRMHRIYHSGETEDASWFLRWLQRE. . FGHAPTAAVGYSLGGNMLACLLAKEGNDLPVDAAVIVSAPFMLEAC
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Template Sequence  YQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSG. . VFKCGIAVAPVSRWEYY
Template Known Secondary structure  SS
GGGTT
TTSTTSSSTTS


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GGGS
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   585....590.........600.........610.........620.........630.........640..... ....650.........660..
 
   188.190.........200.........210.........220.........230.........240.........250.........260.......
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Query Sequence  SYHMEKGFSRVYQRYLLNLLKANAARKLAAYPGTLPINLAQLKSVRRIREFDDLITARIHGYADAIDYYRQCSAMPMLNR
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Template Sequence  DSVYTE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RYMGLPTPEDNLDHYRNSTVMSRAEN
Template Known Secondary structure  B................................................

SSTTTTT
SGGGGGG
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   663..... .670.........680.........690....
 
   268. 270.........280..... ....290.........300.........310.........320.........330.....
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Query Sequence  IA. KPTLIIHAKDDPFMDH. . . . QVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTYL
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Template Sequence  FKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDH. . . . GIASSTAHQHIYTHMSHFIKQCF
Template Known Secondary structure  GGGSTT
SSS
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   695....700.........710.........720.........730.........740 .........750.........760...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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