|   |
54 | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
. | . | . | . | . | . | . | 80 | . | . | . | . | |
|
|
. | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
. | . | . | 120 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . |
|  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
D | G | D | F | V | D | L | A | W | S | E | N | P | A | Q | A | Q | H | K | . |
. |
P | R | L | V | V | F | H | G | L | E | G | S | . |
. |
. |
L | N | S | P | Y | A | H | G | L | V | E | A | A | Q | K | R | G | W | L | G | V | V | M | H | F | R | G | C | S | G | E | P | . |
. |
. |
. |
N | R | M | H | R | I | Y | H |
Query Conservation |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |
|   |
|
|
|
|
|
|   |   |
|   | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |
|   |
|   | . | . | . | . |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | D | Y | N | L | P | M | Q | I | L | K | P | A | T | F | T | D | T | T | H | Y | P | L | L | L | V | V | D | G | T | P | G | S | Q | S | V | A | E | K | F | E | V | S | W | E | T | V | M | V | S | S | H | G | A | V | V | V | K | C | D | G | R | G | S | G | F | Q | G | T | K | L | L | H | E | V | R | R | R | L | G |
Template Known Secondary structure |   |
T | T |  |  |  |
|
| B |  |  | B |
| S | S |
|
| S | S | S |
|  |  |  |  |  |  |
|
|
|
| T | T |
|
|
|
|
|
|
|
|
|
| S |  |  |  |  |  |  |  | T | T |
|
|  |  |  |
|
|
|
| T | T |
| S | S | S |  |  |  |  |  |  | T | T | T | T |
| T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
602 | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . |
  |
  |   |
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
|
. | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | |
|
|
|
. | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | G | E | T | E | D | A | S | W | F | L | R | W | L | Q | R | E | . |
. |
F | G | H | A | P | T | A | A | V | G | Y | S | L | G | G | N | M | L | A | C | L | L | A | K | . |
. |
. |
. |
E | G | N | D | L | P | V | D | A | A | V | I | V | S | A | P | F | M | L | E | A | C | S | Y | H | M | E | K | G | F | S | R | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |
|   |
|   |
|   |
|   |
|
|   |
|
|   |   |   |
|   |   | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |
|   |
|   |
|   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
L | L | E | E | K | D | Q | M | E | A | V | R | T | M | L | K | E | Q | Y | I | D | R | T | R | V | A | V | F | G | K | D | Y | G | G | Y | L | S | T | Y | I | L | P | A | K | G | E | N | Q | G | Q | . |
. |
T | F | T | C | G | S | A | L | S | P | I | T | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |
|
|
|
| S | S | S | T | T |
|
| . | . |
|
| S |  |  |  |  |  | S |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
682 | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | |
|
. | . | . | . | . | . | . | . | 740 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | |
270 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | Q | R | Y | L | L | N | L | L | K | A | N | A | A | R | K | L | A | A | Y | P | G | T | L | P | I | N | L | A | Q | L | K | S | V | R | R | I | R | E | F | D | D | L | I | T | A | R | I | H | G | Y | A | D | A | I | D | Y | Y | R | Q | C | S | A | M | P | M | L | N | R | I | A | . |
K | P | T | L | I | I | H | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   | . |   |
|
|
|
|
|   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | K | L | Y | A | S | A | F | S | E | R | Y | L | G | L | H | G | L | D | N | R | A | Y | E | M | T | K | V | A | H | R | V | S | A | L | E | E | Q | Q | F | L | I | I | H | P |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T | S | S | B |  |  |  |  |  |  |  |  |
|
|
| S | S |
|
| S | S | T | T | T | S |
| T |  |  |  |  | T | S |
|
| S |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
745 | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . |
  |
  |   |
278 | . | 280 | . | . | . | . | . | . | . | |
|
|
|
. | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | D | D | P | F | M | D | H | Q | V | . |
. |
. |
. |
I | P | K | P | E | S | L | P | P | Q | V | E | Y | Q | L | T | E | H | G | G | H | V | G | F | I | G | G | T | L | L | H | P | Q | M | W | L | E | S | R | I | P | D | W | L | T | T | Y | L | E |
Query Conservation |   |
  |   |
|   |   |
|
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
| . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | A | D | E | K | I | H | F | Q | H | T | A | E | L | I | T | Q | L | I | R | G | K | A | N | Y | S | L | Q | I | Y | P | D | E | S | H | . |
. |
. |
. |
Y | F | T | S | S | S | L | K | Q | H | L | Y | R | S | I | I | N | F | F | V | E | C | F | R |
Template Known Secondary structure |   |
T | T |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  | T | T |
|
| S | . | . | . | . | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | |
|
|
|
. | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . |
  |