|   |
2 | . | . | . | . | . | . | . | 10 | . | . | |
. | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | I | A | F | I | G | E | A | V | S | G | . |
F | G | G | M | E | T | V | I | R | D | V | I | T | T | F | R | Q | Q | H | I | Q | S | E | M | F | F | F | C | R | N | D | K | M | D | K | G | W | L | E | G | I | K | Y | S | C | S | F | S | N | I | R | L | G | F | L | R | R | A | K | H | I | H | A | L | S | K | W | L |
Query Conservation |   |
|
|
|   |
|   |   |   |   |   |   | . |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
K | T | L | V | V | T | N | D | F | P | P | R | I | G | G | I | Q | S | Y | L | R | D | F | I | A | T | Q | D | P | E | S | I | V | V | F | A | S | T | Q | N | A | E | E | A | H | A | Y | D | K | T | L | D | Y | E | V | I | R | W | P | R | S | V | M | L | P | . |
. |
. |
T | P | T | T | A | H | A | M | A | E | I | I |
Template Known Secondary structure |   |
|  |  |  |  |  | S |
|
| T | T | S |
| S |  |  |  |  |  |  |  |  |  |  |  | T | S |
| G | G | G |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  | T | T |
| S | S |  |  |  |  |  | S | S | S | S |
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
|
. | . | . | . | . | . | . | . | . | 80 | . | . |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | E | Y | Q | P | D | I | V | I | C | I | D | V | I | S | C | L | F | A | A | K | A | R | K | K | S | G | I | D | M | P | V | F | S | W | P | H | F | S | . |
. |
. |
. |
. |
. |
. |
L | D | H | K | K | H | A | E | Y | I | T | C | A | D | Y | H | L | A | I | S | S | G | I | K | Q | Q | M | I | N | R | G | V | A | E |
Query Conservation |   |
  |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | E | R | E | I | D | N | V | W | F | G | A | A | A | P | L | A | L | M | A | G | T | A | K | Q | A | G | A | S | K | V | I | A | S | T | H | G | H | E | V | G | W | S | M | L | P | G | S | R | Q | S | L | R | K | I | G | T | E | V | D | V | L | T | Y | I | S | Q | Y | T | L | R | R | F | K | S | A | F | G | S | H |
Template Known Secondary structure |   |
 |  | T | T |
| S |  |  |  |  | S | S |
| T | T | G | G | G | G |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
|
| S |
| S | S | S | T | T |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  | S |
|  |  |  |  |  |  |  | T | T | T | T |
| S | S |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
  |
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | T | I | N | V | I | F | N | P | V | E | T | K | D | S | V | I | P | A | P | E | E | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
E | T | A | T | F | I | Y | V | G | R | M | K | F | E | G | Q | K | R | V | K | D | L | L | D | G | L | S | Q | A | K | G | N | W | K | L | H | V | L | G | D | G | S | D | F | E | K | C | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | T | F | E | H | L | P | S | G | V | D | V | K | R | F | T | P | A | T | P | E | D | K | S | A | T | R | K | K | L | G | F | T | D | T | T | P | V | I | A | C | N | S | R | L | V | P | R | K | G | Q | D | S | L | I | K | A | M | P | Q | V | I | A | A | R | P | D | A | Q | L | L | I | V | G | S | G | R | Y | E | S |
Template Known Secondary structure |   |
S |  |  |  |  |
|
|
|
| B |
| T | T | T | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|
|  |  |  |  |  | S |
| S | S | G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |
|
|
| T | T |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . |
  |
  |   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Y | G | R | E | L | N | I | D | D | R | I | V | W | Y | G | W | Q | Q | Y | P | W | E | L | V | Q | Q | D | I | E | K | V | S | A | L | L | L | T | . |
. |
. |
. |
. |
. |
. |
S | S | F | E | G | F | P | M | T | L | L | E | A | L | S | W | G | I | P | C | I | S | A | D | C | V | S | G | P | A | D | I | I | Q | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
|   |   |
|   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|
|
|   |
|   |   |   |
|
|   |   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|
|
|
|
|   |
|   |
|
|
|   |
|   | . |   |
|
|   |   |
|   |
|   |   |
Template Sequence |   |
T | L | R | R | L | A | T | D | V | S | . |
Q | N | V | K | F | L | G | R | L | E | Y | Q | D | M | I | N | T | L | A | A | A | D | I | F | A | M | P | A | R | T | R | G | G | G | L | D | V | E | G | L | G | I | V | Y | L | E | A | Q | A | C | G | V | P | V | I | A | G | T | . |
S | G | G | A | P | E | T | V | T | P |
Template Known Secondary structure |   |
 |  |  |  |  | T | G | G | G | G | . | G | G |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |
|
|
|
| B | G | G | G | T | B |
|
|
| S |
|  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  | S | . | S | T | T | G | G | G | G |
|
| T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
243 | . | . | . | . | . | . | 250 | . | . | |
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | |
. | . | . | . | . | . | . | . | . | 320 |
  |
  |   |
298 | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
|
. | 330 | . | . | . | . | . | |
. | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | . | . |  |  |  |  |  |  |  | . |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | V | N | G | H | L | Y | Q | P | G | D | I | A | G | F | V | T | L | L | N | K | Y | I | A | G | E | I | H | I | E | H | . |
. |
E | K | I | P | A | S | I | . |
D | E | F | Y | Q | S | K | Y | Y | D | R | L | H | K | V | I | I | S |
Query Conservation |   |
  |   |   |
|   |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   | . |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . |   |
|   |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
A | . |
T | G | L | V | V | E | G | S | D | V | D | K | L | S | E | L | L | I | E | L | L | D | D | P | I | R | R | A | A | M | G | A | A | G | R | A | H | V | E | A | E | W | S | W | E | I | M | G | E | R | L | T | N | I | L | Q | S |
Template Known Secondary structure |   |
T | . | T |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | B |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
| . |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
321 | |
. | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . |
  |