|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | M | R | I | A | A | I | P | G | D | G | I | G | K | E | V | L | P | E | G | I | R | V | L | Q | A | A | A | E | R | W | G | F | A | L | S | F | E | Q | M | E | W | A | S | C | E | Y | Y | S | H | H | G | K | M | M | P | D | D | W | H | E | Q | L | S | R | F | D | A | I | Y | F | G | A | V | G | W | P | D | T | V |
Query Conservation |   |
  |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
|
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|   |
|   | . | . | . | . |   |   |   |
|
|   |   |   |   |   |   | . |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
| . | . | . |
Template Sequence |   |
A | Y | R | I | C | L | I | E | G | D | G | I | G | H | E | V | I | P | A | A | R | R | V | L | E | A | T | . |
. |
. |
. |
G | L | P | L | E | F | V | E | A | E | A | . |
G | W | E | T | F | E | R | R | G | T | S | V | P | E | E | T | V | E | K | I | L | S | C | H | A | T | L | F | G | A | A | T | V | P | . |
. |
. |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | T |
|
|  |  |  |  |  |  |
|
| . | S |  |  |  |  |  |  |  | S | S | S | S |
|  |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |
|
|
| T | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |
| . |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
| . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
|
|
|
. | 30 | . | . | . | . | . | . | . | . | . | |
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
  |
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | D | H | I | S | L | W | G | S | L | L | K | F | R | R | E | F | D | Q | Y | V | N | L | R | P | V | R | L | F | P | G | V | P | C | P | L | A | G | K | Q | P | G | D | I | D | F | Y | V | V | R | E | N | T | E | G | E | Y | S | S | L | G | G | R | V | N | E | G | T | E | H | E | V | V | I | Q | E | S | V | F | T |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   | . | . | . | . | . | . |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |
|
Template Sequence |   |
. |
. |
. |
. |
G | F | F | G | A | I | R | Y | L | R | R | R | L | D | L | Y | A | N | V | R | P | A | K | S | R | P | V | P | G | . |
. |
. |
. |
. |
. |
S | R | P | G | V | D | L | V | I | V | R | E | N | T | E | G | L | Y | V | E | Q | E | R | R | Y | . |
. |
. |
. |
. |
L | D | V | A | I | A | D | A | V | I | S |
Template Known Secondary structure |   |
. | . | . | . | T |
|
|
|  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |
|
| S | S | T | T | . | . | . | . | . | . |
|
| T | T |
|  |  |  |  |  |  |  |
| G | G | G | T |
|
|
|
|  |  |  |  | . | . | . | . | . | T | T |  |  |  |  |
|
|
|
|
|
Template Predicted Secondary structure |   |
. | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 140 | . | . | . |
  |
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | R | G | V | D | R | I | L | R | Y | A | F | E | L | A | Q | S | R | P | R | K | T | L | T | S | A | T | K | S | N | G | L | A | I | S | M | P | Y | W | D | E | R | V | E | A | M | A | E | N | Y | P | E | I | R | W | D | K | Q | H | I | D | I | L | C | A | R | F | V | M | Q | P | E | R | F | D | V | V | V | A | S |
Query Conservation |   |
|   |   |   |
|
|
|
|
|   |
|
|   |   |
|   |   |   |   |
|
|   |
|
|   |
|   |
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |
|
|   |   |
|   |   |
|
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |
|
|   |
|
|   |
|   |
|
|
|
|   |   |   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |
|
|   |   |
|   |   |
|
|
|
|
|   |   |
Template Sequence |   |
K | K | A | S | E | R | I | G | R | A | A | L | R | I | A | E | G | R | P | R | K | T | L | H | I | A | H | K | A | N | V | L | P | L | T | Q | G | L | F | L | D | T | V | K | E | V | A | K | D | F | P | L | V | N | V | Q | D | I | I | V | D | N | C | A | M | Q | L | V | M | R | P | E | R | F | D | V | I | V | T | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | T | T |
|  |  |  |  |  |  |
| T | T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
| S |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
144 | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
  |
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | L | F | G | D | I | L | S | D | L | G | P | A | C | T | G | T | I | G | I | A | P | S | A | N | L | N | P | E | R | T | F | P | S | L | F | E | P | V | H | G | S | A | P | D | I | Y | G | K | N | I | A | N | P | I | A | T | I | W | A | G | A | M | M | L | D | F | L | G | N | G | D | E | R | F | Q | Q | A | H | N |
Query Conservation |   |
|
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|
|
|
|   |
|
|   |
|
|
|   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |
|   |
|
|
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|
|
|
|   |   |
|   |
|   |
|
|
|
|   |   |
|
|   |
|
|
|   |   |   | . | . | . |
|   |
|
|
|   |
|
|
|
| . | . |
|
|
|
|   |   |
|
|
|   |
|   |
|
|
|   |
|
|
|
|   |   |
|
| . | . | . | . | . |   |   |   |   |
|   |
Template Sequence |   |
N | L | L | G | D | I | L | S | D | L | A | A | G | L | V | G | G | L | G | L | A | P | S | G | N | I | G | D | T | T | . |
. |
. |
A | V | F | E | P | V | H | G | S | A | . |
. |
I | A | G | K | G | I | A | N | P | T | A | A | I | L | S | A | A | M | M | L | D | Y | L | G | . |
. |
. |
. |
. |
E | K | E | A | A | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| G | G | G |
|  |  |  |  |  |
| S | S |
| . | . | . |  |  |  |  |  | S | S |
|
|
| . | . |
|
| S | S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|  |  |  |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | |
|
|
. | . | . | . | . | . | 260 | . | . | . | |
|
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 290 | . | . | . |
  |
  |   |
324 | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | I | L | A | A | I | E | E | V | I | A | H | G | P | K | T | P | D | M | K | G | N | A | T | T | P | Q | V | A | D | A | I | C | K | I | I | L | R |
Query Conservation |   |
  |
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|   |   |   |
|   |
|   |   |   |
|
|   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|   |   |   |
|   |
|   |   |
|
|
|   |   |   |
|   |   |
Template Sequence |   |
R | V | E | K | A | V | D | L | V | L | E | R | G | P | R | T | P | D | L | G | G | D | A | T | T | E | A | F | T | E | A | V | V | E | A | L | K | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | S |
|
|
| G | G | G | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
296 | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
  |