Job Description P76393 Confidence 100.00% Date Thu Jan 5 12:22:31 GMT 2012 Rank 125 Aligned Residues 266 % Identity 15% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

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		15	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.								.	.	.	.	.	40	.	.	.	.	.	.	.	.					.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.
Predicted Secondary structure																						.	.	.	.	.	.	.															.	.	.	.
Query SS confidence																						.	.	.	.	.	.	.															.	.	.	.
Query Sequence		T	T	L	G	R	E	L	G	K	G	G	E	G	A	V	Y	D	I	E	E	.	.	.	.	.	.	.	F	V	D	S	V	A	K	I	Y	H	T	P	P	P	.	.	.	.	A	L	K	Q	D	K	L	A	F	M	A	A	T	A	D	A	Q	L	L	N	Y	V	A	W	P	Q	A	T	L	H	G	G	R	G	G
Query Conservation																						.	.	.	.	.	.	.															.	.	.	.
Alig confidence																						.	.	.	.	.	.	.															.	.	.	.																								.	.	.	.	.
Template Conservation																																																																						.	.	.	.	.
Template Sequence		L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	A	G	P	Q	H	R	S	G	W	K	Q	E	I	D	I	L	R	T	L	Y	H	E	H	I	I	K	Y	K	G	.	.	.	.	.	C	C	E	D	A	G	A
Template Known Secondary structure												S	S										T	T	S	S	S												S	S																						T	T	B						.	.	.	.	.					T	T	T
Template Predicted Secondary structure																																																																						.	.	.	.	.
Template SS confidence
		897	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.						.	.	.	.	.	970	.
		84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	V	I	G	F	M	M	P	K	V	S	G	K	E	P	I	H	M	I	Y	S	P	A	H	R	R	Q	S	Y	P	H	C	A	W	D	F	L	L	Y	V	A	R	N	I	A	S	S	F	A	T	V	H	E	H	G	H	V	V	G	D	V	N	Q	N	S	F	M	V	G	R	D	S	K	V	V	L	I	D	S	D
Query Conservation
Alig confidence																								.	.	.	.	.	.	.	.
Template Conservation																								.	.	.	.	.	.	.	.
Template Sequence		A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	H	.	.	.	.	.	.	.	.	S	I	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	D	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G
Template Known Secondary structure		T										T	T		B					G	G	G	S	.	.	.	.	.	.	.	.																								T	T				S			S	G	G	G						T	T								T
Template Predicted Secondary structure																								.	.	.	.	.	.	.	.
Template SS confidence
		972	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.									.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	F	Q	I	N	A	N	G	T	L	H	L	C	E	V	G	V	S	H	F	T	P	P	E	L	Q	T	L	P	S	F	V	G	F	E	R	T	E	N	H	D	N	F	G	L	A	L	L	I	F	H	V	L	F	G	G	R	H	P	Y	S	G	V	P	L	I	S	D	A	G	N	A	L	E	T	D	I	T	H	F
Query Conservation
Alig confidence																											.	.	.	.	.																								.																				.	.	.	.	.	.
Template Conservation																											.	.	.	.	.																								.																				.	.	.	.	.	.
Template Sequence		L	A	K	A	V	P	E	G	H	E	Y	R	V	G	D	S	P	V	F	W	Y	A	P	E	C	.	.	.	.	.	L	K	E	Y	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	.	T	H	C	D	S	S	Q	S	P	P	T	K	F	L	E	L	I	G	I	.	.	.	.	.	.	A
Template Known Secondary structure		T						T	T				B						G	G	G						.	.	.	.	.			S		B																			.	T	T	T		G	G	G	S											S	.	.	.	.	.	.	T
Template Predicted Secondary structure																											.	.	.	.	.																								.																				.	.	.	.	.	.
Template SS confidence
		1044	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.						.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.		.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110							.
		244	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Y	A	Y	A	S	D	N	Q	R	R	G	L	K	P	P	P	R	S	I	P	L	S	M	L	P	S	D	V	E	A	M	F	Q	Q	A	F	T	E	S	G	V	A	T	G	R	P	T	A	K	A	W	V	A	A	L	D	S	L	R	Q	Q	L	K
Query Conservation
Alig confidence																																										.	.
Template Conservation																																										.	.
Template Sequence		Q	G	Q	M	T	V	L	R	L	T	E	L	L	E	R	G	E	R	L	P	R	P	D	K	C	P	A	E	V	Y	H	L	M	K	N	C	W	E	T	E	.	.	A	S	F	R	P	T	F	E	N	L	I	P	I	L	K	T	V	H	E	K	Y	Q
Template Known Secondary structure		T	G	G	G											T	T							T	T													T		S	S	.	.	G	G	G	S
Template Predicted Secondary structure																																										.	.
Template SS confidence
		1116	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.			.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions