|   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | |
|
|
. | . | . | . | . | 40 | . | . | . | |
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . | . |
|
|  |  |  |  |  |  |  | . | . |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | K | V | F | T | S | T | G | E | L | T | T | L | G | R | E | L | G | K | G | G | E | G | A | V | Y | D | I | E | E | . |
. |
. |
F | V | D | S | V | A | K | I | Y | . |
. |
H | T | P | P | P | A | L | K | Q | D | K | L | A | F | M | A | A | T | A | D | A | Q | L | L | N | Y | V | A | W | P | Q | A | T | L | H | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |
|   |
|
|   |
|   |   | . | . | . |   |   |   |
|
|   |
|   |   | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |
|
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |
|   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   | . |
|
|   |   |   |   |   |
Template Sequence |   |
Q | V | P | H | D | H | V | A | Y | R | Y | E | V | L | K | V | I | G | K | G | S | F | G | Q | V | V | K | A | Y | D | H | K | V | H | Q | H | V | A | L | K | M | V | R | N | E | K | R | F | H | R | Q | A | A | E | E | I | R | I | L | E | H | L | R | K | Q | D | K | D | N | T | M | N | . |
V | I | H | M | L | E | N |
Template Known Secondary structure |   |
|
| T | T |
|  |  | T | T | T |  |  |  |  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T | S |
| S |
| . | B |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
139 | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
. | . | . | . | . | . | . |
  |
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | |
|
. |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
Query Sequence |   |
G | R | G | G | K | V | I | G | F | M | M | P | K | V | S | G | K | E | P | I | H | M | I | Y | S | P | A | H | R | R | Q | S | Y | P | H | C | A | W | D | F | L | L | Y | V | A | R | N | I | A | S | S | F | A | T | V | H | E | H | G | H | V | V | G | D | V | N | Q | N | S | F | M | V | G | R | D | S | K | . |
. |
V |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |
|   | . | . |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |   | . |   |   |   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | T | F | R | N | H | I | C | M | T | F | E | L | L | . |
S | M | N | L | Y | E | L | I | K | K | N | K | F | Q | . |
. |
. |
. |
. |
G | F | S | L | P | L | V | R | K | F | A | H | S | I | L | Q | C | L | D | A | L | H | K | N | R | I | I | H | C | D | L | K | P | E | N | I | L | L | K | Q | Q | G | R | S | G | I |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |  |  |  |  |
|
|
| . |
|
| B |  |  |  |  |  |  |  | T | T | T |
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |
| S |
|
| S | G | G | G |  |  |  | S | S | T | T | S |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
218 | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | |
. | . | . | . | . | . | . | . | 240 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . |
  |
  |   |
158 | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | I | D | S | D | S | F | Q | I | N | A | N | G | T | L | H | L | C | E | V | G | V | S | H | F | T | P | P | E | L | Q | T | L | P | S | F | V | G | F | E | R | T | E | N | H | D | N | F | G | L | A | L | L | I | F | H | V | L | F | G | G | R | H | P | Y | S | G | V | P | L | I | S | D | A | G | N | A | L | E |
Query Conservation |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|
|
|   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
K | V | I | D | F | G | S | S | C | Y | E | H | Q | R | V | Y | . |
. |
. |
. |
. |
. |
. |
. |
T | I | Q | S | R | F | Y | R | A | P | E | V | I | L | G | A | R | Y | G | M | P | I | D | M | W | S | L | G | C | I | L | A | E | L | L | . |
T | G | Y | P | L | L | P | G | E | D | E | G | D | Q | L | A | C | M | I | E |
Template Known Secondary structure |   |
 |  |
|
|
| T | T |
|  |  | T | T |
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
| G | G | G |
|
|  |  |  |  |  | T | B |
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  | S | S |
| S | S |
|
| S | S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
292 | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | |
. | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
  |
  |   |
238 | . | 240 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | D | I | T | H | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | Y | A | Y | A | S | D | N | Q | R | R | G | L | K | P | P | P | R | S | I | P | L | S | M | L | P | S | D | V | E | A | M | F | Q | Q | A | F | T | E | S |
Query Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |   |
|
Template Sequence |   |
L | L | G | M | P | S | Q | K | L | L | D | A | S | K | R | A | K | N | F | V | S | K | G | Y | P | R | Y | C | T | V | T | T | L | S | D | V | V | L | N | G | G | R | S | R | R | G | K | L | R | G | P | P | E | S | R | E | W | G | N | A | L | K | G | C | D | D | P | L | F | L | D | F | L | K | Q | C | L | E | W | D |
Template Known Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  | T | B | T | T |  |  |  |  | B |
|
|
|
| B | T | T | S |
|  |  |
|
|
|
|
|  |  |
|
|  |  |
| T | T |
|
|  |  |
| S | T | T |
| S |
|  |  |  |  | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
364 | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . |
  |
  |   |
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | A | T | G | R | P | T | A | K | A | W | V | A | A |
Query Conservation |   |
  |   |
|   |   |
|
|
|   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |
|   |   |
|
|
|
|   |
|
|
|   |
|
Template Sequence |   |
. |
. |
P | A | V | R | M | T | P | G | Q | A | L | R | H |
Template Known Secondary structure |   |
. | . | T | T | T | S |
|
|  |  |  |  |  | T | S |
Template Predicted Secondary structure |   |
. | . |  |  |  |
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
447 | . | . | 450 | . | . | . | . | . | . | . | . | . |
  |