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Job DescriptionP76393
Confidence100.00%DateThu Jan 5 12:22:31 GMT 2012
Rank182Aligned Residues240
% Identity15%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   5....10.........20.........30.... .....40.........50.........60.........70.........80..
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Query Sequence  IKVFTSTGELTTLGRELGKGGEGAVYDIEE. . FVDSVAKIYHTPPPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRG
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMI. . . . . KEFIEEAKVMMNLSHEKLVQL. . . . . . . YGVCTK
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   392.......400.........410.........420.........430.. .......440.........450... ......
 
   83......90.........100.........110.........120.........130.........140.........150.........160..
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Query Sequence  GKVIGFMMPKVSGKEPIHMIYSPAHRRQSYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLIDS
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Template Sequence  QRPIFIITEYMANGCLLNYLREMRH. . . . . . RFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDF
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   467..470.........480.........490. ........500.........510.........520.........530.........540
 
   163......170.........180.........190.........200.........210.........220.........230.........240..
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Query Sequence  DSFQINANGTLHLCEVGVSHFTPPELQTLPSFVGFERTENHDNFGLALLIFHVLFGGRHPYSGVPLISDAGNALETDITH
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Template Sequence  GF. . . . . . . . . . . . . . . . . . . . PVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL.
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   541. .......550.........560.........570.........580.........590.........
 
   243......250.........260.........270.........280.........290.........300.....
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Query Sequence  FRYAYASDNQRRGLKPPPRSIPLSMLPSDVEAMFQQAFTESGVATGRPTAKAWVAALDSLRQQ
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Template Sequence  . . . . . . . . . . . . . . . . . . . . YRPHLASEKVYTIMYSCWHEK. . ADERPTFKILLSNILDVMDE
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   617..620.........630....... ..640.........650.......
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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