Job Description P76393 Confidence 100.00% Date Thu Jan 5 12:22:31 GMT 2012 Rank 119 Aligned Residues 262 % Identity 13% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		15	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.								.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.
Predicted Secondary structure																					.	.	.	.	.	.	.
Query SS confidence																					.	.	.	.	.	.	.
Query Sequence		T	T	L	G	R	E	L	G	K	G	G	E	G	A	V	Y	D	I	E	.	.	.	.	.	.	.	E	F	V	D	S	V	A	K	I	Y	H	T	P	P	P	A	L	K	Q	D	K	L	A	F	M	A	A	T	A	D	A	Q	L	L	N	Y	V	A	W	P	Q	A	T	L	H	G	G	R	G	G	K	V	I	G
Query Conservation																					.	.	.	.	.	.	.
Alig confidence																					.	.	.	.	.	.	.																.																								.	.	.	.	.	.	.	.
Template Conservation																																											.																								.	.	.	.	.	.	.	.
Template Sequence		L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	P	H	I	A	.	D	L	K	K	E	I	E	I	L	R	N	L	Y	H	E	N	I	V	K	Y	K	G	I	.	.	.	.	.	.	.	.	C	T	E	N	G	I	K
Template Known Secondary structure												S	S										T	T	S	S	S		S														.											T				T	T	B							.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																											.																								.	.	.	.	.	.	.	.
Template SS confidence
		875	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.		.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.									.	940	.	.	.	.	.
		88	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	M	M	P	K	V	S	G	K	E	P	I	H	M	I	Y	S	P	A	H	R	R	Q	S	Y	P	H	C	A	W	D	F	L	L	Y	V	A	R	N	I	A	S	S	F	A	T	V	H	E	H	G	H	V	V	G	D	V	N	Q	N	S	F	M	V	G	R	D	S	K	V	V	L	I	D	S	D	S	F	Q	I
Query Conservation
Alig confidence																						.	.	.	.	.	.
Template Conservation																						.	.	.	.	.	.
Template Sequence		L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	.	.	.	.	.	.	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I	G	D	F	G	L	T	K	A
Template Known Secondary structure								T	T		B					T	G	G	G	T	T	.	.	.	.	.	.	T																							T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure																						.	.	.	.	.	.
Template SS confidence
		954	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.							.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.
		168	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	A	N	G	T	L	H	L	C	E	V	G	V	S	H	F	T	P	P	E	L	Q	T	L	P	S	F	V	G	F	E	R	T	E	N	H	D	N	F	G	L	A	L	L	I	F	H	V	L	F	G	G	R	H	P	Y	S	G	V	P	L	I	S	D	A	G	N	A	L	E	T	D	I	T	H	F	R	Y	A	Y
Query Conservation
Alig confidence													.	.	.																																				.								.	.	.	.	.	.
Template Conservation													.	.	.																																				.								.	.	.	.	.	.
Template Sequence		I	E	T	D	K	E	T	V	K	D	D	.	.	.	R	D	S	P	V	F	W	Y	A	P	E	C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	.	T	Y	C	D	S	D	S	.	.	.	.	.	.	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M
Template Known Secondary structure				T	T					S			.	.	.	T	T			G	G	G																													.	T	T	T		G	G	G	.	.	.	.	.	.												S			G	G	G
Template Predicted Secondary structure													.	.	.																																				.								.	.	.	.	.	.
Template SS confidence
		1028	.	1030	.	.	.	.	.	.	.	.				.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.		.	.	.	.	.	.	1080							.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.
		248	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	S	D	N	Q	R	R	G	L	K	P	P	P	R	S	I	P	L	S	M	L	P	S	D	V	E	A	M	F	Q	Q	A	F	T	E	S	G	V	A	T	G	R	P	T	A	K	A	W	V	A	A	L	D	S	L	R
Query Conservation
Alig confidence																																						.	.
Template Conservation																																						.	.
Template Sequence		T	V	T	R	L	V	N	T	L	K	E	G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	M	R	K	C	W	E	F	Q	.	.	P	S	N	R	T	S	F	Q	N	L	I	E	G	F	E	A	L	L
Template Known Secondary structure												T	T							T	T												T			S	S	.	.	G	G	G	S												T	T
Template Predicted Secondary structure																																						.	.
Template SS confidence
		1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.			.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions