Return to main results Retrieve Phyre Job Id

Job DescriptionP76393
Confidence100.00%DateThu Jan 5 12:22:31 GMT 2012
Rank66Aligned Residues256
% Identity17%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   8.10.........20.........30.........40.... .....50.........60.........70.........80..
Predicted Secondary structure 









.....











Query SS confidence 




































. . . . .





































Query Sequence  FTSTGELTTLGRELGKGGEGAVYDIEEFVDSVAKIYH. . . . . TPPPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRG
Query Conservation           
   

 

 
 

 
     

 
   .....         
                            
Alig confidence 




































.....


























........


Template Conservation   

    
     

 
 

 

       



                 
   
  
 




    ........   
Template Sequence  WEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMG. . . . . . . . YST
Template Known Secondary structure 
B

TT

TTSSS

SSS

TT


TTB

........
Template Predicted Secondary structure 



























........


Template SS confidence 















































































   450.........460.........470.........480.........490.........500.........510........ .520.
 
   83......90.........100.........110.........120.........130.........140.........150.........160..
Predicted Secondary structure 





























Query SS confidence 















































































Query Sequence  GKVIGFMMPKVSGKEPIHMIYSPAHRRQSYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLIDS
Query Conservation       



   
  
   
            
          

  

  

  








 



   
 


 

Alig confidence 
























......
















































Template Conservation       
  
      
         ......                                                 
Template Sequence  KPQLAIVTQWCEGSSLYHHLHIIET. . . . . . KFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDF
Template Known Secondary structure  SSS


SS
BTS

......


TT
B
S

SGGGTTT


Template Predicted Secondary structure 














......


























Template SS confidence 















































































   522.......530.........540...... ...550.........560.........570.........580.........590.....
 
   163......170.........180.........190.........200.........210.........220.........230.........240..
Predicted Secondary structure 













































Query SS confidence 















































































Query Sequence  DSFQINANGTLHLCEVGVSHFTPPELQTLPSFVGFERTENHDNFGLALLIFHVLFGGRHPYSGVPLISDAGNALETDITH
Query Conservation 
 
             


   


  


   
      







 


 
  
  

 
                 
Alig confidence 



.........

















..




















.






















..
Template Conservation      .........          

      ..        





 





.

  

            
    ..
Template Sequence  GLAT. . . . . . . . . VLSGSILWMAPEVIRMQD. . KNPYSFQSDVYAFGIVLYELM. TGQLPYSNINNRDQIIFMVGRGY. .
Template Known Secondary structure  TT
B.........





TT

TT
S..S


S.SS
TTTT


TS..
Template Predicted Secondary structure 



.........













..







.












..
Template SS confidence 















































































   596... 600.........610....... ..620.........630........ .640.........650.........660.
 
   243......250.........260.........270.........280.........290.........300.......
Predicted Secondary structure 































Query SS confidence 
































































Query Sequence  FRYAYASDNQRRGLKPPPRSIPLSMLPSDVEAMFQQAFTESGVATGRPTAKAWVAALDSLRQQLK
Query Conservation                               
  

   
     
  


       
        
Alig confidence  ..............


























..





















Template Conservation  ..............                  

  

  
..
  


  

   
  
   

Template Sequence  . . . . . . . . . . . . . . LSPDLSKVRSNCPKAMKRLMAECLKKK. . RDERPLFPQILASIELLARSLP
Template Known Secondary structure  ..............



GGGS
TTS
T
SS..GGGS

T

Template Predicted Secondary structure  ..............













..




Template SS confidence 
































































   674.....680.........690.........700 .........710.........720..
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions