Phyre 2 alignment of P76393 with c2vx3D

Job Description P76393
Confidence 99.94% Date Thu Jan 5 12:22:31 GMT 2012

Rank 254 Aligned Residues 278

% Identity 11% Template c2vx3D_

PDB info PDB header:transferase Chain: D: PDB Molecule:dual specificity tyrosine-phosphorylation- regulated PDBTitle: crystal structure of the human dual specificity tyrosine-2 phosphorylation-regulated kinase 1a

Resolution 2.40 Å

	Insertion relative to template
	Deletion relative to template
	Catalytic residue from the CSA

Detailed help on interpreting your alignment

	5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.				.	.	.	.	.	40	.	.	.			.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																															.	.	.										.	.
Query SS confidence																															.	.	.										.	.
Query Sequence	I	K	V	F	T	S	T	G	E	L	T	T	L	G	R	E	L	G	K	G	G	E	G	A	V	Y	D	I	E	E	.	.	.	F	V	D	S	V	A	K	I	Y	.	.	H	T	P	P	P	A	L	K	Q	D	K	L	A	F	M	A	A	T	A	D	A	Q	L	L	N	Y	V	A	W	P	Q	A	T	L	H	G
Query Conservation																															.	.	.										.	.
Alig confidence																															.	.	.										.	.																													.
Template Conservation																																																																									.
Template Sequence	V	K	N	G	E	K	W	M	D	R	Y	E	I	D	S	L	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	R	V	E	Q	E	W	V	A	I	K	I	I	K	N	K	K	A	F	L	N	Q	A	Q	I	E	V	R	L	L	E	L	M	N	K	H	D	T	E	M	K	Y	Y	.	I	V	H	L	K	R	H
Template Known Secondary structure			T	T				T	T	T											T	T									T	T	T	T										S	S																				S	S	S	S	G	G	G	G	.	B
Template Predicted Secondary structure																																																																									.
Template SS confidence
	149	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220		.	.	.	.	.	.	.

	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.					.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Predicted Secondary structure																																																												.	.	.	.
Query SS confidence																																																												.	.	.	.
Query Sequence	G	R	G	G	K	V	I	G	F	M	M	P	K	V	S	G	K	E	P	I	H	M	I	Y	S	P	A	H	R	R	Q	S	Y	P	H	C	A	W	D	F	L	L	Y	V	A	R	N	I	A	S	S	F	A	T	V	H	E	H	G	.	.	.	.	H	V	V	G	D	V	N	Q	N	S	F	M	V	G	R	D	S
Query Conservation																																																												.	.	.	.
Alig confidence																													.	.	.	.	.	.																										.	.	.	.
Template Conservation																													.	.	.	.	.	.
Template Sequence	F	M	F	R	N	H	L	C	L	V	F	E	M	L	S	Y	N	L	Y	D	L	L	R	N	T	N	F	R	.	.	.	.	.	.	G	V	S	L	N	L	T	R	K	F	A	Q	Q	M	C	T	A	L	L	F	L	A	T	P	E	L	S	I	I	H	C	D	L	K	P	E	N	I	L	L	C	N	P	K	R	S
Template Known Secondary structure				T	T												B								T	T	T		.	.	.	.	.	.																							S	T	T	T					S				G	G	G				S	S	T	T	S
Template Predicted Secondary structure																													.	.	.	.	.	.
Template SS confidence
	228	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.							.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.

	156	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence	K	V	V	L	I	D	S	D	S	F	Q	I	N	A	N	G	T	L	H	L	C	E	V	G	V	S	H	F	T	P	P	E	L	Q	T	L	P	S	F	V	G	F	E	R	T	E	N	H	D	N	F	G	L	A	L	L	I	F	H	V	L	F	G	G	R	H	P	Y	S	G	V	P	L	I	S	D	A	G	N	A
Query Conservation
Alig confidence																			.	.	.	.	.	.	.	.																																				.
Template Conservation																			.	.	.	.	.	.	.	.																																				.
Template Sequence	A	I	K	I	V	D	F	G	S	S	C	Q	L	G	Q	R	I	Y	.	.	.	.	.	.	.	.	Q	I	Q	S	R	F	Y	R	S	P	E	V	L	L	G	M	P	Y	D	L	A	I	D	M	W	S	L	G	C	I	L	V	E	M	H	.	T	G	E	P	L	F	S	G	A	N	E	V	D	Q	M	N	K	I
Template Known Secondary structure								T	T				T	T					.	.	.	.	.	.	.	.					G	G	G							T	T					T																.		S	S		S	S			S	S
Template Predicted Secondary structure																			.	.	.	.	.	.	.	.																																				.
Template SS confidence
	302	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.									320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.		.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.

	236	.																																								.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Predicted Secondary structure			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence	L	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	D	I	T	H	F	R	Y	A	Y	A	S	D	N	Q	R	R	G	L	K	P	P	P	R	S	I	P	L	S	M	L	P	S	D	V	E	A	M	F
Query Conservation			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence	V	E	V	L	G	I	P	P	A	H	I	L	D	Q	A	P	K	A	R	K	F	F	E	K	L	P	D	G	T	W	N	L	K	K	T	K	R	E	Y	K	P	P	G	T	R	K	L	H	N	I	L	G	V	E	T	G	G	P	G	G	R	R	A	G	E	S	G	H	T	V	A	D	Y	L	K	F	K	D	L	I
Template Known Secondary structure						S							T	T		T	T	G	G	G	T					T	T	S											S			T	T		S						T	T	T	T	T	T	S	G	G	G	T	T	T	T		T	T
Template Predicted Secondary structure
Template SS confidence
	374	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.

	277	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Predicted Secondary structure
Query SS confidence
Query Sequence	Q	Q	A	F	T	E	S	G	V	A	T	G	R	P	T	A	K	A	W	V	A	A	L	D
Query Conservation
Alig confidence								.	.
Template Conservation								.	.
Template Sequence	L	R	M	L	D	Y	D	.	.	P	K	T	R	I	Q	P	Y	Y	A	L	Q	H	S	F
Template Known Secondary structure				T		S		.	.	T	T	T	S								T	S	G	G
Template Predicted Secondary structure								.	.
Template SS confidence
	457	.	.	460	.	.	.			.	.	.	.	.	.	470	.	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys
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