Job Description P76393 Confidence 100.00% Date Thu Jan 5 12:22:31 GMT 2012 Rank 92 Aligned Residues 234 % Identity 14% Template c2r7bA_ PDB info PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor Resolution 2.70 Å

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		15	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.				.	.	.	.	.	40	.	.	.	.							.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.
Predicted Secondary structure																						.	.	.											.	.	.	.	.	.
Query SS confidence																						.	.	.											.	.	.	.	.	.
Query Sequence		T	T	L	G	R	E	L	G	K	G	G	E	G	A	V	Y	D	I	E	E	.	.	.	F	V	D	S	V	A	K	I	Y	H	.	.	.	.	.	.	T	P	P	P	A	L	K	Q	D	K	L	A	F	M	A	A	T	A	D	A	Q	L	L	N	Y	V	A	W	P	Q	A	T	L	H	G	G	R	G	G	K	V
Query Conservation																						.	.	.											.	.	.	.	.	.
Alig confidence																						.	.	.											.	.	.	.	.	.																										.	.	.	.	.	.	.
Template Conservation																																																																		.	.	.	.	.	.	.
Template Sequence		F	K	F	G	K	I	L	G	E	G	S	F	S	T	V	V	L	A	R	E	L	A	T	S	R	E	Y	A	I	K	I	L	E	K	R	H	I	I	K	E	N	K	V	P	Y	V	T	R	E	R	D	V	M	S	R	L	D	H	P	F	F	V	K	L	.	.	.	.	.	.	.	Y	F	T	F	Q	D	D	E	K
Template Known Secondary structure												S	S									T	T	T																	T	T														T				T	T	B				.	.	.	.	.	.	.							S	S
Template Predicted Secondary structure																																																																		.	.	.	.	.	.	.
Template SS confidence
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.								.	.	.	.	150	.	.	.	.
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	G	F	M	M	P	K	V	S	G	K	E	P	I	H	M	I	Y	S	P	A	H	R	R	Q	S	Y	P	H	C	A	W	D	F	L	L	Y	V	A	R	N	I	A	S	S	F	A	T	V	H	E	H	G	H	V	V	G	D	V	N	Q	N	S	F	M	V	G	R	D	S	K	V	V	L	I	D	S	D	S	F
Query Conservation
Alig confidence																							.	.	.	.	.	.	.
Template Conservation																							.	.	.	.	.	.	.
Template Sequence		L	Y	F	G	L	S	Y	A	K	N	G	E	L	L	K	Y	I	R	K	I	G	.	.	.	.	.	.	.	S	F	D	E	T	C	T	R	F	Y	T	A	E	I	V	S	A	L	E	Y	L	H	G	K	G	I	I	H	R	D	L	K	P	E	N	I	L	L	N	E	D	M	H	I	Q	I	T	D	F	G	T	A
Template Known Secondary structure										T	T		B								S	S	.	.	.	.	.	.	.	S																							T	T								T	T	T					T	T	S								T	T
Template Predicted Secondary structure																							.	.	.	.	.	.	.
Template SS confidence
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.								.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.
		166	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	I	N	A	N	G	T	L	H	L	C	E	V	G	V	S	H	F	T	P	P	E	L	Q	T	L	P	S	F	V	G	F	E	R	T	E	N	H	D	N	F	G	L	A	L	L	I	F	H	V	L	F	G	G	R	H	P	Y	S	G	V	P	L	I	S	D	A	G	N	A	L	E	T	D	I	T	H	F	R	Y
Query Conservation
Alig confidence					.	.	.	.	.	.	.	.	.	.	.	.	.																																				.																								.	.	.	.	.
Template Conservation					.	.	.	.	.	.	.	.	.	.	.	.	.																																				.																								.	.	.	.	.
Template Sequence		K	V	L	.	.	.	.	.	.	.	.	.	.	.	.	.	F	V	G	T	A	Q	Y	V	S	P	E	L	L	T	E	K	S	A	C	K	S	S	D	L	W	A	L	G	C	I	I	Y	Q	L	V	.	A	G	L	P	P	F	R	A	G	N	E	Y	L	I	F	Q	K	I	I	K	L	E	Y	.	.	.	.	.
Template Known Secondary structure					.	.	.	.	.	.	.	.	.	.	.	.	.					G	G	G								S	S																				.		S	S		S				S	S											T			.	.	.	.	.
Template Predicted Secondary structure					.	.	.	.	.	.	.	.	.	.	.	.	.																																				.																								.	.	.	.	.
Template SS confidence
		228	.	230														.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.		.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.
		246	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Predicted Secondary structure
Query SS confidence
Query Sequence		A	Y	A	S	D	N	Q	R	R	G	L	K	P	P	P	R	S	I	P	L	S	M	L	P	S	D	V	E	A	M	F	Q	Q	A	F	T	E	S	G	V	A	T	G	R	P	T	A	K	A	W	V	A	A	L	D
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	F	P	E	K	F	F	P	K	A	R	D	L	V	E	K	L	L	V	L	D	.	.	A	T	K	R	L	G	C	E	E	M	E	G	Y	G	P
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.				S	S	S										T	T	S		S	S	.	.	T	T	S	S	T	T	S	G	G	G	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.
Template SS confidence
																			300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320			.	.	.	.	.	.	.	.	.	330	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions