Job Description P76393 Confidence 99.97% Date Thu Jan 5 12:22:31 GMT 2012 Rank 222 Aligned Residues 273 % Identity 13% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.				.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80
Predicted Secondary structure																																	.	.	.
Query SS confidence																																	.	.	.
Query Sequence		N	I	K	V	F	T	S	T	G	E	L	T	T	L	G	R	E	L	G	K	G	G	E	G	A	V	Y	D	I	E	E	.	.	.	F	V	D	S	V	A	K	I	Y	H	T	P	P	P	A	L	K	Q	D	K	L	A	F	M	A	A	T	A	D	A	Q	L	L	N	Y	V	A	W	P	Q	A	T	L	H	G	G
Query Conservation																																	.	.	.
Alig confidence																																	.	.	.																																						.	.	.	.	.
Template Conservation																																																																									.	.	.	.	.
Template Sequence		A	L	T	V	Q	W	G	E	Q	D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	N	N	N	E	K	C	I	I	K	I	L	K	P	V	K	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P	N	I	V	K	L	L	D	.	.	.	.	.	I	V	R	D
Template Known Secondary structure		G								G	G	G											S	S									T	T	T											S																			T	T	B						.	.	.	.	.
Template Predicted Secondary structure																																																																									.	.	.	.	.
Template SS confidence
		28	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.						.	100	.	.
		81	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.		.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																									.
Query SS confidence																																																																									.
Query Sequence		R	G	G	K	V	I	G	F	M	M	P	K	V	S	G	K	E	P	I	H	M	I	Y	S	P	A	H	R	R	Q	S	Y	P	H	C	A	W	D	F	L	L	Y	V	A	R	N	I	A	S	S	F	A	T	V	H	E	H	G	H	V	V	G	D	V	N	Q	N	S	F	M	V	.	G	R	D	S	K	V	V	L
Query Conservation																																																																									.
Alig confidence																										.	.	.	.	.	.	.	.	.	.																																						.
Template Conservation																										.	.	.	.	.	.	.	.	.	.
Template Sequence		Q	H	S	K	T	P	S	L	I	F	E	Y	V	N	N	T	D	F	K	V	L	Y	P	T	.	.	.	.	.	.	.	.	.	.	L	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C	H	S	Q	G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L
Template Known Secondary structure		T	T	T																			G	G	G	.	.	.	.	.	.	.	.	.	.																							T	T							S	G	G	G					T	T	T	T
Template Predicted Secondary structure																										.	.	.	.	.	.	.	.	.	.
Template SS confidence
		104	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.											.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.
		160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.
Predicted Secondary structure																																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		I	D	S	D	S	F	Q	I	N	A	N	G	T	L	H	L	C	E	V	G	V	S	H	F	T	P	P	E	L	Q	T	L	P	S	F	V	G	F	E	R	T	E	N	H	D	N	F	G	L	A	L	L	I	F	H	V	L	F	G	G	R	H	P	Y	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																															.	.	.	.																									.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																															.	.	.	.																									.
Template Sequence		I	D	W	G	L	A	E	F	Y	H	P	G	K	E	Y	N	V	R	V	A	S	R	Y	F	K	G	P	E	L	.	.	.	.	L	V	D	L	Q	D	Y	D	Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	.	F	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V
Template Known Secondary structure					T	T						T	T					S			S		G	G	G						.	.	.	.		T	T			S			T																.		T		S	S	S	S			S	S
Template Predicted Secondary structure																															.	.	.	.																									.
Template SS confidence
		174	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.					.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.		.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
			225	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	G	V	P	L	I	S	D	A	G	N	A	L	E	T	D	I	T	H	F	R	Y	A	Y	A	S	D	N	Q	R	R	G	L	K	P	P	P	R	S	I	P	L	S	M	L	P	S	D	V	E	A	M	F	Q	Q	A	F	T	E	S	G	V	A	T	G	R	P	T	A	K	A	W	V	A	A
Query Conservation		.
Alig confidence		.																																																												.	.
Template Conservation																																																														.	.
Template Sequence		L	G	T	D	G	L	N	A	Y	L	N	K	Y	R	I	E	L	D	P	Q	L	E	A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	A	I	D	F	L	D	K	L	L	R	Y	D	.	.	H	Q	E	R	L	T	A	L	E	A	M	T	H
Template Known Secondary structure														T	T																			G	G	G	G			T	T	T	G	G	G											T	T			S	S	.	.	T	T	T	S									S
Template Predicted Secondary structure																																																														.	.
Template SS confidence
		249	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.			.	310	.	.	.	.	.	.	.	.	.	320	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions