|   |
27 | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | |
. | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | V | F | R | E | L | E | T | R | R | T | L | R | F | E | L | S | G | K | S | Y | F | L | K | W | H | K | G | T | T | L | K | E | I | I | K | N | L | L | S | L | R | M | P | V | L | G | A | D | R | E | W | H | A | I | H | R | L | S | D | V | G | . |
V | D | T | M | K | G | I | G | F | G | E | K | G | L | N | P | L |
Query Conservation |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   | . |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |
|   |
|
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   | . | . | . | . | . | . |
Template Sequence |   |
E | K | L | Y | S | G | E | X | N | E | I | W | L | I | N | D | E | V | Q | T | V | F | V | K | I | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | R | S | Y | R | S | X | F | R | A | E | A | D | Q | L | A | L | L | A | K | T | N | S | I | N | V | P | L | V | Y | G | I | G | N | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |
|
| S | S | S | S |  |  |  |  |  |  | S | S | S |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | B |
|
|
|  |  |  |  |  |  | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
23 | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
|
|
|
|
|
  |
  |   |
106 | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
T | R | A | S | F | I | I | T | E | D | L | T | P | T | I | S | . |
. |
. |
. |
. |
. |
. |
. |
L | E | D | Y | C | A | D | W | A | V | N | P | P | D | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | Q | G | H | S | F | L | L | L | E | A | L | N | K | S | K | N | K | Q | S | S | F | T | I | F | A | E | K | I | A | Q | L | H | Q | I | Q | G | P | D | K | Y | G | L | D | F | D | T | W | L | G | P | I | Y | Q | P | N | D | W | Q | T | S | W | A | K | F | F | S | E | N | R | I | G | W | Q | L | Q | I | C | K | E |
Template Known Secondary structure |   |
| S | S |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| S | S | B | B |
| S | S |
|  |  |  | T | T |  |  |  |
|
|
|
| B | S |
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
  |
  |   |
|
|
|
|
|
137 | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | |
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 |
Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
R | V | K | R | M | L | I | A | R | V | A | T | M | V | R | K | M | H | . |
T | A | G | I | N | H | R | D | C | Y | I | C | H | F | L | L | H | L | P | F | T | G | R | E | D | E | L | K | I | S | V | I | D | L | H | R | A | Q | I | R | A | K | V | P | R | R | W | R | D | K | D | L | I | G | L | Y |
Query Conservation |   |
. | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
| . |   |   |
|
|   |
|
|
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |
|
|
|
|   | . |   |   |   |
|
|   |
|   |
|
|
|   |   |   |
|
|
|   |
|   |
Template Sequence |   |
K | G | L | I | F | G | N | I | D | L | I | V | Q | I | V | A | D | T | L | S | K | H | N | P | K | P | S | I | L | H | G | N | L | W | I | E | N | C | I | Q | V | D | D | . |
. |
. |
. |
. |
. |
. |
. |
K | I | F | V | C | N | P | A | . |
C | Y | W | G | D | R | E | C | D | I | A | F | S | S | L | F | E | P | F | P |
Template Known Secondary structure |   |
 | T |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |
| S | S |
| S | G | G | G |  |  |  |  | T | T | . | . | . | . | . | . | . | . |  |  |  |  |
| S |
|
| . |
|  |  |  |
| T |  |  |  |  |  |  |  | T | T | S | S |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
| . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|  | . |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | 210 | . | . | . | |
. | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . |
  |
  |   |
211 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | S | . |
. |
. |
. |
. |
. |
. |
S | M | N | I | G | L | T | Q | R | D | I | W | R | F | M | K | V | Y | F | G | M | P | L | R | K | I | L | . |
S | L | E | Q | N | L | L | N | M | A | S | V | K | A | E | R | I | K | E | R |
Query Conservation |   |
  |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|
|   |
|
|   |   |
|   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
Template Sequence |   |
T | N | F | Y | Q | R | Y | N | E | I | Y | P | L | E | E | G | Y | L | E | R | K | L | I | Y | Q | L | Y | Y | L | L | N | F | S | Y | R | Y | Y | N | K | K | Q | S | Y | V | S | L | T | Q | K | L | I | N | Q | I | L | H | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | S |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
  |