Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	L	L	Q	R	G	V	A	L	A	L	L	T	T	F	T	L	A	S	E	T	A	L	A	Y	E	Q	D	K	T	Y	K	I	T	V	L	H	T	N	D	H	H	G	H	F	W	R	N	E	Y	G	E	Y	G	L	A	A	Q	K
Secondary structure
SS confidence
Disorder		?	?	?																?	?	?	?	?	?	?	?	?		?																						?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	L	V	D	G	I	R	K	E	V	A	A	E	G	G	S	V	L	L	L	S	G	G	D	I	N	T	G	V	P	E	S	D	L	Q	D	A	E	P	D	F	R	G	M	N	L	V	G	Y	D	A	M	A	I	G	N	H	E	F	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	P	L	T	V	L	R	Q	Q	E	K	W	A	K	F	P	L	L	S	A	N	I	Y	Q	K	S	T	G	E	R	L	F	K	P	W	A	L	F	K	R	Q	D	L	K	I	A	V	I	G	L	T	T	D	D	T	A	K	I	G	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	E	Y	F	T	D	I	E	F	R	K	P	A	D	E	A	K	L	V	I	Q	E	L	Q	Q	T	E	K	P	D	I	I	I	A	A	T	H	M	G	H	Y	D	N	G	E	H	G	S	N	A	P	G	D	V	E	M	A	R	A	L
Secondary structure
SS confidence
Disorder																																												?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	A	G	S	L	A	M	I	V	G	G	H	S	Q	D	P	V	C	M	A	A	E	N	K	K	Q	V	D	Y	V	P	G	T	P	C	K	P	D	Q	Q	N	G	I	W	I	V	Q	A	H	E	W	G	K	Y	V	G	R	A	D	F
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?	?	?		?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		E	F	R	N	G	E	M	K	M	V	N	Y	Q	L	I	P	V	N	L	K	K	K	V	T	W	E	D	G	K	S	E	R	V	L	Y	T	P	E	I	A	E	N	Q	Q	M	I	S	L	L	S	P	F	Q	N	K	G	K	A	Q	L
Secondary structure
SS confidence
Disorder																						?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		E	V	K	I	G	E	T	N	G	R	L	E	G	D	R	D	K	V	R	F	V	Q	T	N	M	G	R	L	I	L	A	A	Q	M	D	R	T	G	A	D	F	A	V	M	S	G	G	G	I	R	D	S	I	E	A	G	D	I	S	Y
Secondary structure
SS confidence
Disorder																																																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		K	N	V	L	K	V	Q	P	F	G	N	V	V	V	Y	A	D	M	T	G	K	E	V	I	D	Y	L	T	A	V	A	Q	M	K	P	D	S	G	A	Y	P	Q	F	A	N	V	S	F	V	A	K	D	G	K	L	N	D	L	K	I
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		K	G	E	P	V	D	P	A	K	T	Y	R	M	A	T	L	N	F	N	A	T	G	G	D	G	Y	P	R	L	D	N	K	P	G	Y	V	N	T	G	F	I	D	A	E	V	L	K	A	Y	I	Q	K	S	S	P	L	D	V	S	V
Secondary structure
SS confidence
Disorder																																																								?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550
Sequence		Y	E	P	K	G	E	V	S	W	Q
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1oid chain A Region: 26 - 550 Aligned: 525 Modelled: 525 Confidence: 100.0% Identity: 100% PDB header:hydrolase Chain: A: PDB Molecule:protein usha; PDBTitle: 5'-nucleotidase (e. coli) with an engineered disulfide2 bridge (s228c, p513c) Phyre2 PDB 2z1a chain A Region: 32 - 548 Aligned: 479 Modelled: 485 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase precursor from thermus2 thermophilus hb8 Phyre2 PDB 2wdf chain A Region: 29 - 550 Aligned: 458 Modelled: 472 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:sulfur oxidation protein soxb; PDBTitle: termus thermophilus sulfate thiohydrolase soxb Phyre2 PDB 3zu0 chain A Region: 30 - 550 Aligned: 498 Modelled: 509 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:nad nucleotidase; PDBTitle: structure of haemophilus influenzae nad nucleotidase (nadn) Phyre2 PDB 3ivd chain A Region: 31 - 539 Aligned: 465 Modelled: 477 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:nucleotidase; PDBTitle: putative 5'-nucleotidase (c4898) from escherichia coli in2 complex with uridine Phyre2 PDB 3qfk chain A Region: 33 - 550 Aligned: 466 Modelled: 479 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: 2.05 angstrom crystal structure of putative 5'-nucleotidase from2 staphylococcus aureus in complex with alpha-ketoglutarate Phyre2 PDB 3c9f chain B Region: 34 - 498 Aligned: 434 Modelled: 441 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase from candida albicans sc5314 Phyre2 PDB 3jyf chain B Region: 29 - 361 Aligned: 308 Modelled: 329 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:2',3'-cyclic nucleotide 2'-phosphodiesterase/3'- PDBTitle: the crystal structure of a 2,3-cyclic nucleotide 2-2 phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor3 protein from klebsiella pneumoniae subsp. pneumoniae mgh 78578 Phyre2 PDB 1ush chain A domain 2 Region: 26 - 361 Aligned: 326 Modelled: 336 Confidence: 100.0% Identity: 100% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain Phyre2 PDB 3gve chain B Region: 30 - 362 Aligned: 303 Modelled: 314 Confidence: 100.0% Identity: 23% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:yfkn protein; PDBTitle: crystal structure of calcineurin-like phosphoesterase yfkn from2 bacillus subtilis Phyre2 PDB 2z1a chain A domain 2 Region: 32 - 358 Aligned: 291 Modelled: 298 Confidence: 100.0% Identity: 29% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain Phyre2 PDB 1ush chain A domain 1 Region: 363 - 550 Aligned: 188 Modelled: 188 Confidence: 100.0% Identity: 100% Fold: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Superfamily: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Phyre2 PDB 3c9f chain A domain 2 Region: 34 - 357 Aligned: 297 Modelled: 305 Confidence: 100.0% Identity: 16% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain Phyre2 PDB 2z1a chain A domain 1 Region: 360 - 548 Aligned: 186 Modelled: 189 Confidence: 100.0% Identity: 33% Fold: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Superfamily: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Phyre2 PDB 1t71 chain A Region: 33 - 328 Aligned: 256 Modelled: 283 Confidence: 100.0% Identity: 15% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: DR1281-like Phyre2 PDB 1t70 chain A Region: 34 - 257 Aligned: 177 Modelled: 205 Confidence: 100.0% Identity: 20% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: DR1281-like Phyre2 PDB 2z06 chain A domain 1 Region: 34 - 298 Aligned: 201 Modelled: 231 Confidence: 99.9% Identity: 20% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: TTHA0625-like Phyre2 PDB 3c9f chain A domain 1 Region: 361 - 534 Aligned: 171 Modelled: 171 Confidence: 99.9% Identity: 10% Fold: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Superfamily: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Phyre2 PDB 2xmo chain B Region: 29 - 314 Aligned: 260 Modelled: 264 Confidence: 99.6% Identity: 15% PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 Phyre2 PDB 3t1i chain C Region: 33 - 360 Aligned: 291 Modelled: 299 Confidence: 99.6% Identity: 15% PDB header:hydrolase Chain: C: PDB Molecule:double-strand break repair protein mre11a; PDBTitle: crystal structure of human mre11: understanding tumorigenic mutations Phyre2 1 c1oidA_ 2 c2z1aA_ 3 c2wdfA_ 4 c3zu0A_ 5 c3ivdA_ 6 c3qfkA_ 7 c3c9fB_ 8 c3jyfB_ 9 d1usha2 10 c3gveB_ 11 d2z1aa2 12 d1usha1 13 d3c9fa2 14 d2z1aa1 15 d1t71a_ 16 d1t70a_ 17 d2z06a1 18 d3c9fa1 19 c2xmoB_ 20 c3t1iC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1oidA_ 100.0 100 PDB header:hydrolase Chain: A: PDB Molecule:protein usha; PDBTitle: 5'-nucleotidase (e. coli) with an engineered disulfide2 bridge (s228c, p513c) 2 c2z1aA_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase precursor from thermus2 thermophilus hb8 3 c2wdfA_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:sulfur oxidation protein soxb; PDBTitle: termus thermophilus sulfate thiohydrolase soxb 4 c3zu0A_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:nad nucleotidase; PDBTitle: structure of haemophilus influenzae nad nucleotidase (nadn) 5 c3ivdA_ 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:nucleotidase; PDBTitle: putative 5'-nucleotidase (c4898) from escherichia coli in2 complex with uridine 6 c3qfkA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: 2.05 angstrom crystal structure of putative 5'-nucleotidase from2 staphylococcus aureus in complex with alpha-ketoglutarate 7 c3c9fB_ 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase from candida albicans sc5314 8 c3jyfB_ 100.0 23 PDB header:hydrolase Chain: B: PDB Molecule:2',3'-cyclic nucleotide 2'-phosphodiesterase/3'- PDBTitle: the crystal structure of a 2,3-cyclic nucleotide 2-2 phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor3 protein from klebsiella pneumoniae subsp. pneumoniae mgh 78578 9 d1usha2 100.0 100 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 10 c3gveB_ 100.0 23 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:yfkn protein; PDBTitle: crystal structure of calcineurin-like phosphoesterase yfkn from2 bacillus subtilis 11 d2z1aa2 100.0 29 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 12 d1usha1 100.0 100 Fold:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Superfamily:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Family:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 13 d3c9fa2 100.0 16 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 14 d2z1aa1 100.0 33 Fold:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Superfamily:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Family:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 15 d1t71a_ 100.0 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DR1281-like 16 d1t70a_ 100.0 20 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DR1281-like 17 d2z06a1 99.9 20 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TTHA0625-like 18 d3c9fa1 99.9 10 Fold:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Superfamily:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain Family:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 19 c2xmoB_ 99.6 15 PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 20 c3t1iC_ 99.6 15 PDB header:hydrolase Chain: C: PDB Molecule:double-strand break repair protein mre11a; PDBTitle: crystal structure of human mre11: understanding tumorigenic mutations 21 c3ib7A_ not modelled 99.5 19 PDB header:hydrolase Chain: A: PDB Molecule:icc protein; PDBTitle: crystal structure of full length rv0805 22 d1ii7a_ not modelled 99.5 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DNA double-strand break repair nuclease 23 c3qg5D_ not modelled 99.5 13 PDB header:hydrolase Chain: D: PDB Molecule:mre11; PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair 24 c3av0A_ not modelled 99.5 15 PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11-rad50 bound to atp s 25 d2yvta1 not modelled 99.4 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 26 c3auzA_ not modelled 99.4 14 PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11 with manganese 27 d1utea_ not modelled 99.4 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 28 d1uf3a_ not modelled 99.4 16 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 29 c2q8uA_ not modelled 99.4 15 PDB header:hydrolase Chain: A: PDB Molecule:exonuclease, putative; PDBTitle: crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at2 2.20 a resolution 30 d1qhwa_ not modelled 99.3 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 31 c1qhwA_ not modelled 99.3 15 PDB header:hydrolase Chain: A: PDB Molecule:protein (purple acid phosphatase); PDBTitle: purple acid phosphatase from rat bone 32 c1kbpB_ not modelled 99.3 14 PDB header:hydrolase (phosphoric monoester) Chain: B: PDB Molecule:purple acid phosphatase; PDBTitle: kidney bean purple acid phosphatase 33 c1xzwB_ not modelled 99.3 12 PDB header:hydrolase Chain: B: PDB Molecule:purple acid phosphatase; PDBTitle: sweet potato purple acid phosphatase/phosphate complex 34 d2qfra2 not modelled 99.3 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 35 d1xzwa2 not modelled 99.3 11 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 36 d3d03a1 not modelled 99.2 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 37 d2nxfa1 not modelled 99.2 13 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:ADPRibase-Mn-like 38 d2hy1a1 not modelled 99.0 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 39 c2hy1A_ not modelled 99.0 15 PDB header:hydrolase Chain: A: PDB Molecule:rv0805; PDBTitle: crystal structure of rv0805 40 d1s3la_ not modelled 98.9 22 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 41 c1s3mA_ not modelled 98.9 22 PDB header:phosphodiesterase Chain: A: PDB Molecule:hypothetical protein mj0936; PDBTitle: structural and functional characterization of a novel2 archaeal phosphodiesterase 42 c3rl4A_ not modelled 98.9 15 PDB header:hydrolase Chain: A: PDB Molecule:metallophosphoesterase mpped2; PDBTitle: rat metallophosphodiesterase mpped2 g252h mutant 43 c3qfnA_ not modelled 98.7 17 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of streptococcal asymmetric ap4a hydrolase and2 phosphodiesterase spr1479/saph in complex with inorganic phosphate 44 d1su1a_ not modelled 98.6 23 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 45 c1su1A_ not modelled 98.6 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein yfce; PDBTitle: structural and biochemical characterization of yfce, a2 phosphoesterase from e. coli 46 d2a22a1 not modelled 98.6 16 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 47 c2kknA_ not modelled 98.6 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of themotoga maritima protein tm1076:2 northeast structural genomics consortium target vt57 48 d1z2wa1 not modelled 98.6 20 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 49 d1xm7a_ not modelled 98.5 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Hypothetical protein aq 1666 50 d1nnwa_ not modelled 98.4 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Phosphoesterase-related 51 d3ck2a1 not modelled 98.4 19 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 52 c3rqzC_ not modelled 98.3 18 PDB header:hydrolase Chain: C: PDB Molecule:metallophosphoesterase; PDBTitle: crystal structure of metallophosphoesterase from sphaerobacter2 thermophilus 53 c2dfjA_ not modelled 97.3 25 PDB header:hydrolase Chain: A: PDB Molecule:diadenosinetetraphosphatase; PDBTitle: crystal structure of the diadenosine tetraphosphate2 hydrolase from shigella flexneri 2a 54 c2qjcA_ not modelled 96.9 28 PDB header:hydrolase Chain: A: PDB Molecule:diadenosine tetraphosphatase, putative; PDBTitle: crystal structure of a putative diadenosine tetraphosphatase 55 c2zbmA_ not modelled 96.4 25 PDB header:hydrolase Chain: A: PDB Molecule:protein-tyrosine-phosphatase; PDBTitle: crystal structure of i115m mutant cold-active protein2 tyrosine phosphatase 56 d1g5ba_ not modelled 96.0 24 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 57 c3icfB_ not modelled 93.7 23 PDB header:hydrolase Chain: B: PDB Molecule:serine/threonine-protein phosphatase t; PDBTitle: structure of protein serine/threonine phosphatase from saccharomyces2 cerevisiae with similarity to human phosphatase pp5 58 d3c5wc1 not modelled 93.0 19 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 59 d1s70a_ not modelled 92.9 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 60 d1s95a_ not modelled 92.8 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 61 d1jk7a_ not modelled 92.6 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 62 c1wao4_ not modelled 91.1 22 PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure 63 c2jogA_ not modelled 91.0 19 PDB header:hydrolase Chain: A: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha PDBTitle: structure of the calcineurin-nfat complex 64 c1auiA_ not modelled 87.3 18 PDB header:hydrolase Chain: A: PDB Molecule:serine/threonine phosphatase 2b; PDBTitle: human calcineurin heterodimer 65 d1auia_ not modelled 87.3 18 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 66 d2p6ba1 not modelled 86.2 19 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 67 c2p6bC_ not modelled 83.8 20 PDB header:hydrolase/hydrolase regulator Chain: C: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha PDBTitle: crystal structure of human calcineurin in complex with2 pvivit peptide 68 d1vp8a_ not modelled 39.6 19 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 69 c2eq5D_ not modelled 39.6 13 PDB header:isomerase Chain: D: PDB Molecule:228aa long hypothetical hydantoin racemase; PDBTitle: crystal structure of hydantoin racemase from pyrococcus horikoshii ot3 70 d1ptma_ not modelled 30.2 21 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like 71 c3t0pB_ not modelled 29.8 8 PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii, beta subunit; PDBTitle: crystal structure of a putative dna polymerase iii beta subunit2 (eubrec_0002; ere_29750) from eubacterium rectale atcc 33656 at 2.263 a resolution 72 c1vlvA_ not modelled 29.4 22 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution 73 c3sdsA_ not modelled 23.9 18 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, mitochondrial; PDBTitle: crystal structure of a mitochondrial ornithine carbamoyltransferase2 from coccidioides immitis 74 c2p2gD_ not modelled 23.8 18 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form 75 d1t57a_ not modelled 23.6 20 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 76 d1vpka1 not modelled 19.6 22 Fold:DNA clamp Superfamily:DNA clamp Family:DNA polymerase III, beta subunit 77 d1djqa1 not modelled 18.2 7 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 78 c1fvoB_ not modelled 17.5 17 PDB header:transferase Chain: B: PDB Molecule:ornithine transcarbamylase; PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate 79 c2bpbA_ not modelled 16.6 17 PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite\:cytochrome c oxidoreductase subunit a; PDBTitle: sulfite dehydrogenase from starkeya novella 80 c2qs0A_ not modelled 16.6 21 PDB header:biosynthetic protein Chain: A: PDB Molecule:quinolinate synthetase a; PDBTitle: quinolinate synthase from pyrococcus furiosus 81 d1vjda_ not modelled 15.6 15 Fold:Phosphoglycerate kinase Superfamily:Phosphoglycerate kinase Family:Phosphoglycerate kinase 82 c1vpkA_ not modelled 14.8 7 PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii, beta subunit; PDBTitle: crystal structure of dna polymerase iii, beta subunit (tm0262) from2 thermotoga maritima at 2.00 a resolution 83 d1pv8a_ not modelled 14.4 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 84 d1r8ka_ not modelled 14.0 26 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like 85 d1ltka_ not modelled 13.9 27 Fold:Phosphoglycerate kinase Superfamily:Phosphoglycerate kinase Family:Phosphoglycerate kinase 86 c3pg8B_ not modelled 13.7 11 PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima 87 d2hawa1 not modelled 13.3 16 Fold:DHH phosphoesterases Superfamily:DHH phosphoesterases Family:Manganese-dependent inorganic pyrophosphatase (family II) 88 c2ixaA_ not modelled 13.2 15 PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase; PDBTitle: a-zyme, n-acetylgalactosaminidase 89 c2eb0B_ not modelled 13.2 16 PDB header:hydrolase Chain: B: PDB Molecule:manganese-dependent inorganic pyrophosphatase; PDBTitle: crystal structure of methanococcus jannaschii putative family ii2 inorganic pyrophosphatase 90 c2pjuD_ not modelled 13.0 14 PDB header:transcription Chain: D: PDB Molecule:propionate catabolism operon regulatory protein; PDBTitle: crystal structure of propionate catabolism operon2 regulatory protein prpr 91 d1ok7a1 not modelled 13.0 16 Fold:DNA clamp Superfamily:DNA clamp Family:DNA polymerase III, beta subunit 92 d1phpa_ not modelled 11.9 28 Fold:Phosphoglycerate kinase Superfamily:Phosphoglycerate kinase Family:Phosphoglycerate kinase 93 c2w37A_ not modelled 11.6 14 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic; PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii 94 d7reqa2 not modelled 11.5 12 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 95 d1v6sa_ not modelled 11.3 16 Fold:Phosphoglycerate kinase Superfamily:Phosphoglycerate kinase Family:Phosphoglycerate kinase 96 c2hi1A_ not modelled 10.8 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 2; PDBTitle: the structure of a putative 4-hydroxythreonine-4-phosphate2 dehydrogenase from salmonella typhimurium. 97 c1unnA_ not modelled 10.7 9 PDB header:beta-clamp Chain: A: PDB Molecule:dna polymerase iii beta subunit; PDBTitle: complex of beta-clamp processivity factor and little finger2 domain of poliv 98 d1vpka2 not modelled 10.4 8 Fold:DNA clamp Superfamily:DNA clamp Family:DNA polymerase III, beta subunit 99 c3opyL_ not modelled 10.4 25 PDB header:transferase Chain: L: PDB Molecule:6-phosphofructo-1-kinase gamma-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0