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Job DescriptionP07024
Confidence99.55%DateThu Jan 5 11:00:06 GMT 2012
Rank20Aligned Residues291
% Identity15%Templatec3t1iC_
PDB info PDB header:hydrolaseChain: C: PDB Molecule:double-strand break repair protein mre11a; PDBTitle: crystal structure of human mre11: understanding tumorigenic mutations
Resolution3.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  KITVLHTNDHHGHFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFRGMNL. . . . . .
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Template Sequence  TFKILVATDIH. . LGFXEKDAVRGNDTFVTLDEILRLAQENEVDFILL. GGDLFHENKPSRKTLHTCLELLRKYCXGDRP
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Query Sequence  . . . . . . . . . . . . . VGYDAMAI. GNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKRQDLKIAVIGLTT
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Template Sequence  VQFEILSDQSNLNISIPVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSXSVEKIDISP. VLLQKGSTKIALYGLGS
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   8990.........100.........110.........120.........130.........140.........150 .........160.......
 
   173......180.........190.........200.........210.........220.........230.........240.........250..
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Query Sequence  DDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHMGHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGH
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Template Sequence  IPDERLYRXFVNKKVTXLRP. . . . . . . . . . . KEDENSWFNLFVIHQNRSKHGSTNFIP. . . . . . . EQFLDDFIDLVIWGH
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   184.....190.........200... ......210.........220.........230 .........240.....
 
   253......260.........270.........280.........290 .........300.........310.........320...
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Query Sequence  SQDPVCMAAENKKQVDYVPGTPCKPDQQNGIWIVQAHE. . . . . . . . . WGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKV
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Template Sequence  EHECKIAP. . . . . . . . . . . . . . . TKNEQQLFYISQPGSSVVTSLSPGEAVKKHVGLLRIKGRKXNXHKIPLHTVRQFFXE
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   246...250... ......260.........270.........280.........290.........300.........310
 
   324.....330.........340.........350.........360
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Query Sequence  TWEDGKSERVLYTPEIAENQQMISLLSPFQNKGKAQL
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Template Sequence  DIVLANHPDIFNPDNPKVTQAIQSFCLEKIEEXLENA
Template Known Secondary structure  GGG
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   311........320.........330.........340.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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