|   |
29 | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
| . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
D | K | T | Y | K | I | T | V | L | H | T | N | D | H | H | G | H | F | W | R | N | E | Y | . |
. |
. |
. |
. |
. |
G | E | Y | G | L | A | A | Q | K | T | L | V | D | G | I | R | K | E | V | A | A | E | G | G | S | V | L | L | L | S | G | G | D | I | N | T | G | V | P | E | S | D | L | . |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|   |
|   |
|   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |   |   |
|   |
|
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |
| . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | A | T | V | D | L | R | I | X | E | T | T | D | L | H | S | N | X | X | D | F | D | Y | Y | K | D | A | A | T | E | K | F | G | L | V | R | T | A | S | L | I | E | Q | A | R | . |
. |
. |
. |
A | E | V | K | N | S | V | L | V | D | N | G | D | V | I | Q | G | S | P | L | G | D | Y | X | A | A | K | G | L | K | E |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
| T | T |
|
| S | S |  |  | T | T | T | T |  |  |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  | T |
| S |
|  |  |  |  |  |
| S |
|
| S | S | S | S |  |  |  |  |  |  |  |  |  |
|
|
| T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
|
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
95 | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
160 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
Q | D | A | E | P | D | F | R | G | M | N | L | V | G | Y | D | A | M | A | I | G | N | H | E | F | D | N | P | L | T | V | L | R | Q | Q | E | K | W | A | K | F | P | L | L | S | A | N | I | Y | Q | K | S | T | G | E | R | L | F | K | P | W | A | L | F | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | Q | D | L | K | I |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |
|
|
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   | . | . | . | . | . | . | . | . | . |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |
|
|
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
Template Sequence |   |
G | D | V | H | P | V | Y | K | A | X | N | T | L | N | Y | A | V | G | N | L | G | N | H | E | F | N | Y | G | L | D | F | L | H | K | A | L | A | G | A | K | F | P | Y | V | N | A | N | I | I | D | A | K | T | G | K | P | X | F | T | P | Y | L | I | Q | D | T | R | V | V | D | S | D | G | Q | I | H | T | L | R | I |
Template Known Secondary structure |   |
T |
|
|
|  |  |  |  |  |  | T | T | S |
|
| S |  |  |  |
|
| G | G | G | G | T | T |
|  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |
| S | S |  |  |  | T | T | T | T |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
166 | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | V | I | G | L | T | T | D | D | T | A | K | I | G | N | P | E | Y | F | T | D | I | E | F | R | K | P | A | D | E | A | K | L | V | I | Q | E | L | Q | Q | T | E | K | P | D | I | I | I | A | A | T | H | M | G | H | Y | D | N | G | E | H | G | S | N | A | P | G | D | V | E | M | A | R | A | L | P | A | G | S | L |
Query Conservation |   |
  |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|   | . |   |   |   |
|
|
|
|   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |
|   |   |   |   |
|
|
Template Sequence |   |
G | Y | I | G | F | V | P | P | Q | I | X | T | W | D | K | A | N | L | N | G | K | V | T | V | N | D | I | T | E | T | A | R | K | Y | I | P | E | X | R | A | . |
K | G | A | D | V | V | V | V | V | A | H | S | G | L | S | A | D | P | Y | Q | A | X | A | E | . |
. |
. |
N | S | V | Y | Y | L | S | Q | V | P | G | V |
Template Known Secondary structure |   |
 |  |  |  |  |
|
| T | T |  |  |  |  | T |  |  |  |  | T | T | T |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | T |
| S |  |  |  |  |  |  |
|
|
|
|
|
| S |
|
|
| T | T |
| S | . | . | . |
|
|  |  |  |  | T | T | S | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | |
|
|
. | . | . | . | . | . | 230 | . | . | . | . | . |
  |
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | |
|
|
|
. | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | M | I | V | G | G | H | S | Q | D | P | V | C | M | A | A | E | N | K | K | Q | V | D | Y | V | P | G | T | P | C | K | P | D | Q | Q | N | G | I | W | I | V | Q | A | H | E | W | G | K | Y | V | G | R | A | D | F | E | F | R | N | G | . |
. |
. |
. |
E | M | K | M | V | N | Y | Q | L | I | P | V | N | L | K | K |
Query Conservation |   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |
|
|   |
|   |
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|   |
|   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | A | I | X | F | G | H | A | H | A | V | F | . |
. |
. |
. |
. |
P | G | K | D | F | A | N | I | K | G | A | D | I | A | K | G | T | L | N | G | V | P | A | V | X | P | G | X | W | G | D | H | L | G | V | V | D | L | V | L | N | N | D | S | G | K | W | Q | V | T | Q | S | K | A | E | A | R | P | I | Y | D | A | V |
Template Known Secondary structure |   |
|  |  |  |
|
| S | S |
|
|  |  | . | . | . | . | . | S | S | G | G | G | T | T | S | T | T |  |  | T | T | T | T |  |  | T | T |  |  |  |  |  |  |
| S | T | T | S |  |  |  |  |  |  |  |  |  |  |
| T | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  | S |  |  | T | T |
Template Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 |
  |
  |   |
322 | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | V | T | W | E | D | G | K | S | E | R | V | L | Y | T | P | E | I | A | E | N | Q | Q | M | I | S | L | L | S | P | F | Q | N | K | G | K | A | Q | L | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
A | K | K | S | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | A | E | D | G | K | L | V | S | V | L | K | A | D | H | D | A | T | R | E | F | V | S |
Template Known Secondary structure |   |
T | T |  |  | S | . | . | . | . | . | . | . | . | . | . | . | . | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
311 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
  |