|   |
29 | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | K | T | Y | K | I | T | V | L | H | T | N | D | H | H | G | H | F | W | R | N | E | Y | G | E | Y | G | L | A | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | K | T | L | V | D | G | I | R | K | E | V | A | A | E | G | G | S | V | L | L | L | S | G | G | D | I | N | T | G | V | P | E | S | D | L |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |
|   |   |
|
|
|
|
| . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|   | . |   |
|
|
|
|   |   |
|   |   |   |   |   |
Template Sequence |   |
E | K | D | R | N | L | S | M | V | V | T | T | D | V | H | . |
. |
Y | F | A | P | S | L | T | D | N | G | K | A | F | E | K | Y | V | A | A | G | D | G | K | Q | L | A | Y | S | D | E | I | T | D | A | F | L | A | D | V | E | S | K | K | T | D | V | L | I | I | . |
S | G | D | L | T | N | N | G | E | K | T | S | H |
Template Known Secondary structure |   |
| S |
| S |
|  |  |  |  |  |  |
|
|
|
| . | . | B |
|
| G | G | G | B |
|
|
|  |  |  |  |  |  |  |  | T | S | T | T |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  | . |  | S |
|
| B | S | S |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . |  |
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
35 | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
|
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . |
  |
  |   |
95 | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
. | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | D | A | E | P | D | F | R | G | M | N | L | V | G | Y | D | A | M | A | I | . |
G | N | H | E | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | N | P | L | T | V | L | R | Q | Q | E | K | W | A | K | F | P | L | L | S | A | N | I | Y | Q | K | S | T | G | E | R | L | F | K | P | W | A |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   | . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
E | E | L | A | K | K | L | T | Q | V | E | K | N | G | T | Q | V | F | V | V | P | G | N | H | D | I | N | N | P | W | A | R | K | F | E | K | D | K | Q | L | P | T | D | T | I | S | P | T | D | F | S | K | I | Y | S | D | F | G | . |
. |
. |
. |
. |
. |
. |
Y | E | D | A | I | S | S | D | E | F | S | L | S | Y | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
| T | T | T | S | S |
| T | T |
|  |  |  |  | T | T |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | T |
|
|
|
| . | . | . | . | . | . | . |
| T | T |
| S |  |  |
| S | S | S | S |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
112 | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
  |
  |   |
157 | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | |
|
. | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
Query Sequence |   |
L | F | K | R | Q | D | L | K | I | A | V | I | G | L | T | T | D | D | T | A | K | I | G | N | P | E | Y | F | T | D | I | E | F | R | K | P | A | D | E | A | K | L | V | I | Q | E | L | Q | Q | T | E | K | P | D | I | I | I | A | A | T | H | M | G | H | Y | D | N | G | E | H | G | S | N | A | . |
. |
P | G | D | V |
Query Conservation |   |
|   |   |   |   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|
|
|   |   |
|   |   |
|   |   | . | . |   |   |   |   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | A | P | S | S | K | V | W | L | L | M | L | D | T | A | I | Y | K | T | N | M | Q | Q | G | N | P | T | T | E | G | G | L | T | A | G | T | L | D | W | I | K | E | S | S | A | L | A | K | K | . |
. |
N | G | A | K | L | I | P | V | L | H | H | N | L | T | D | H | N | D | V | Q | K | G | Y | T | I | N | Y | N | Q |
Template Known Secondary structure |   |
 |
| S | S | S | S |  |  |  |  |  |
|
|
| B |
|
| T | T |  |  |  |  | T | S |
|
|
|
| B |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | T | T |
|  |  |  |  |  |  | S | S | B | S | S |
|
| S |
|
|
| T | T | S | B |
| T | T |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | |
|
. | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
  |
  |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
|
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | M | A | R | A | L | P | A | G | S | L | A | M | I | V | G | G | H | S | Q | D | P | V | C | M | A | A | E | N | K | K | Q | V | D | Y | V | P | G | T | P | C | K | P | D | Q | Q | N | G | I | W | I | V | Q | A | H | E | W | G | . |
. |
. |
K | Y | V | G | R | A | D | F | E | F | R | N | G | E | M | K | M | V | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
| . | . | . |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|
|   |   |   |   |
|   |   |
|
|   |
|
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
Q | V | I | D | A | L | T | E | G | A | M | D | F | S | L | S | G | H | I | H | T | Q | N | I | R | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | K | S | T | D | G | K | E | I | T | D | I | V | T | N | A | L | S | V | F | P | H | K | Y | G | N | I | T | Y | S | A | K | N | K | N | F | T | Y | Q | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S | S |
| S |
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
| T | T | S |
|  |  |  |  |  |  |
|
|
| T | T | S | T | T |
|  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
264 | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . |
  |
  |   |
312 | . | . |
Predicted Secondary structure |   |
 |  |  |
Query SS confidence |   |
|
|
|
Query Sequence |   |
Y | Q | L |
Query Conservation |   |
  |   |   |
Alig confidence |   |
|
|
|
Template Conservation |   |
  |   |
|
Template Sequence |   |
Q | K | L |
Template Known Secondary structure |   |
 |  |
|
Template Predicted Secondary structure |   |
 |  |
|
Template SS confidence |   |
|
|
|
  |   |
330 | . | . |
  |