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Job DescriptionP00959
Confidence100.00%DateThu Jan 5 10:57:21 GMT 2012
Rank8Aligned Residues636
% Identity19%Templatec1wz2B_
PDB info PDB header:ligase/rnaChain: B: PDB Molecule:leucyl-trna synthetase; PDBTitle: the crystal structure of leucyl-trna synthetase and trna(leucine)2 complex
Resolution3.21 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60......
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Query Sequence  TQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQL. . . . . . . . . . . . . . .
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Template Conservation        
 
   


 

 




       

  

 

 
  

   
 
  




  
 
                
Template Sequence  KPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVLFPMAWHITGSPIVGIAERIKNRDPKTIWIYRDVY
Template Known Secondary structure  S
GGG

B


B
SS

BTT


B



BB

SSTT
TTS
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   30.........40.........50.........60.........70.........80.........90.........100.........
 
   67..70.........80.........90 .........100 .........110.........120.........130...
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Query Sequence  . . . . . . . . . GITPEQMIGEMSQEHQTDFAGFNI. . SYDNYHSTHS. . EENRQLSELIYSRLKENGFIKNRTISQLYDPEK
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Template Conservation                               


   

   
 
 
  
     
   
  
   



     
 
 
  
Template Sequence  KVPEEILWTFEDPINIVKYFMKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFWKLKEKGYIVKGAHRVRWDPVV
Template Known Secondary structure 


GGGSTTT



TTS

B
STTSTTTTT






TTT
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   110.........120.........130.........140.........150.........160.........170.........180.........
 
   134.....140.....
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Query Sequence  GMFLPDRFVKGT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation     
 
  
 
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Template Conservation   
 


 

              

 
        
 
 



 

    
  
 
   
           
  
     
Template Sequence  GTPLGDHDLMEGEDVPILDYIIIKFELRENGEVIYLPAATLRPETVYGVTNMWVNPNATYVKAKVRRKDKEETWIVSKEA
Template Known Secondary structure  S
B

SSS
SS









SSS

S
GGGGGG


SSS

SS
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   190.........200.........210.........220.........230.........240.........250.........260.........
 
   146...150.........
Predicted Secondary structure  .......................................................












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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CPKCKSPDQYGDNC. . . . . . . . . . .
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Template Conservation                    
  
 
     
       

    
    


 
   


   
                 
Template Sequence  AYKLSFQDREIEVIEEFKGEKLIGKYVRNPVSGDEVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRETEILEKY
Template Known Secondary structure  SS


SSTTSS

SSSS

SS

SSSTTS

TTS
TTTTTTTS

S

S



TT
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   270.........280.........290.........300.........310.........320.........330.........340.........
 
   160.........170.
Predicted Secondary structure  ....................................................................




Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .











Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EVCGATYSPTEL
Query Conservation  ....................................................................
  
      

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Template Conservation         
         
         
                       
  
  
   
   
   
          
Template Sequence  DIDPRIVFPAVEEVNKLGIKSQKDKEKLEQATKTIYKAEYHKGIFKVPPYEGKPVQEVKEAIAKEMLEKGIAEIMYEFAE
Template Known Secondary structure 








SS

TTTSSS


SS
TTTTS
B

SSSS
SSBTTTTTS


SS
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   350.........360.........370.........380.........390.........400.........410.........420.........
 
   172.......180.........190..... ....200.........210.........220.........230.........240.........
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Query Sequence  IEPKSVVSGATPVMRDSEHFFFDL. . PSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGK
Query Conservation    
                 
  
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Template Conservation        
    
      



       
         
   
          
  
 

 



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Template Sequence  KNVISRFGNRAVIKIIHDQWFIDYGNPEWKEKARKALERMKILPETRRAQFEAIIDWLDKKACARKI. GLGTPLPWDPEW
Template Known Secondary structure  S

B
SSSSB



SS
S

TTTTS
SSTTS




BSS.SSS
TT
TTS
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   446...450.........460.........470.........480.........490.........500.........510.. .......520....
 
   250......... 260.........270.........280....
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Query Sequence  YFYVWLDAPI. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GYMGSFKNLCDKRGDSVSFDEYWKK
Query Conservation 
 


 

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Template Conservation        
  
                              
                  
             
    
 
Template Sequence  VIESLSDSTIYMAYYTISRHINKLRQEGKLDPEKLTPEFFDYIFLEEFSEDKEKELEKKTGIPAEIIHEMKEEFEYWYPL
Template Known Secondary structure 
TTSTTT


GGG

TTTS


T


S
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   525....530.........540.........550.........560.........570.........580.........590.........600....
 
   285....290.........300.........310... ......320.........330.........340.........350.........360..
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Query Sequence  DSTAELYHFIGKDIVYFHSLFWPAMLEGS. . NFRKPSNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTA
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Template Conservation 
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Template Sequence  D. . . . . WRCSGKDLIPNHLTFFIFNHVAIFREEHWPKGIAVNGFGTLEGQKMSKSKGNVLNFIDAIEENGADVVRLYIMS
Template Known Secondary structure  S.....GGGTTTS
STTS




SSS


TTT



BTT
Template Predicted Secondary structure 
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   605 ....610.........620.........630.........640.........650.........660.........670.........
 
   363......370.........380.........390.........400.........410.........420.........430.........440..
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Query Sequence  KLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAV
Query Conservation         
 


           
   
 
   
      
   
       
  
   
      
  
 
      
 
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Template Conservation     .   
  
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Template Sequence  LAE. HDSDFDWRRKEVGKLRK. . QIERFYELISQFAE. . . YEVKGNVELKDIDRWMLHRLNKAIKETTNALEEFRTRTAV
Template Known Secondary structure 

.TT


..S...S








TT
Template Predicted Secondary structure 


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   680.. .......690......... 700.........710... ......720.........730.........740.........750...
 
   443.... ..450.........460.........470.........480.........490.........500.........510.........520.
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Query Sequence  REIMA. LADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLL
Query Conservation    
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Template Conservation       
       
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Template Sequence  QWAFYSIMNDLRWYLRRTEGR. . . . . . . . . . DDEAKRYVLRTLADVWVRLMAPFTPHICEELWEKLGGEGFVSLAKWPEP
Template Known Secondary structure  TTTT
..........

TTTSSS

S
GGGS




Template Predicted Secondary structure 



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   754.....760.........770.... .....780.........790.........800.........810.........820...
 
   522.......530.........540.........550.........560.........570. ........580.........590.........
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Query Sequence  GHKVNPFKALYNRIDMRQVEALVEASKEEVKAAAAPVTGPLADDPIQETI. . TFDDFAKVDLRVALIENAEFVEGSDKLL
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Template Sequence  VEEWWNETIEAEEEFIRSVMEDIKEIIEVAKIENAKRAYIYTAEDWKWKVAEVVSEKRDFKSSMEELMKDSEIRKHGK. .
Template Known Secondary structure 
SS


TS



SB


TTTTTTTTTT
SSSTSTTTTTTGG..
Template Predicted Secondary structure 










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   824.....830.........840.........850.........860.........870.........880.........890.........900.
 
   600.........610.........620.........630.........640.........650.........660.........670
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Query Sequence  RLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGA
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Template Conservation  ........             .        
   
          
  
  
    
   
   
 
 

 
Template Sequence  . . . . . . . . EVAKIVQKLIKER. TFDVKRINEEKALREAKEFMEKELGIEIIINPTEDKGGKKKQAMPLKPA
Template Known Secondary structure  ........GTTTT

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TTTTTTSB


S
SS

SS
TT

BTTB
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   902.......910.... .....920.........930.........940.........950.........960...
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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