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Job DescriptionP00959
Confidence100.00%DateThu Jan 5 10:57:21 GMT 2012
Rank12Aligned Residues488
% Identity24%Templatec1obhA_
PDB info PDB header:synthetaseChain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site
Resolution2.2 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3......10.........20.........30.........40.........50.........60.........70.........80..
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Query Sequence  QVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQ
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Template Sequence  PGGGKQYVLVMFPYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGWDAFGLPAENAALKFGVHPKDWTYANIRQAK
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SS
BT




B


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   2930.........40.........50.........60.........70.........80.........90.........100........
 
   83......90... ......100.........110.........120.........130.........140....
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Query Sequence  TDFAGFNISYD. . NYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKG. . . . . . . . . . . . . . . .
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Template Sequence  ESLRLMGILYDWDREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIG
Template Known Secondary structure  TT



GGG

BTTSTT



GGGGTTTT

S

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   110.........120.........130.........140.........150.........160.........170.........180.........
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  RSEGAEILFPVEGKEVRIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGREKTGV
Template Known Secondary structure  BTT
S
S
GGGGGG


TT
TTTTTS

GGGTS
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TTS


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   226...230.........240.........250.........260.........270.........280.........290.........300.....
 
   145....150.........160.........170..... ....180.........190....
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Query Sequence  . . . . . . . . . . . . . . . . TCPKCKSPDQYGDNCEVCGATYSPTELIEPK. . . . . . . . . . . . . . SVVSGATPVMRDSEHFFFD
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Template Sequence  FLGAYALNPATGERIPIWTADYVLFGYGTGAIMAVPAHDQRDYEFARKFGLPIKKVIERPGEPLPEPLERAYEEPGIMVN
Template Known Secondary structure 
TTT

TTS
SSSTTS
GGG
T





BTTB


SS
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S
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   306...310.........320.........330.........340.........350.........360.........370.........380.....
 
   195....200.........210.........220..... ....230.........240.........
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Query Sequence  LPSFSEMLQAWTRSGALQEQVANKMQEWFES. . . . . . . . . . GLQQWDISRDAPYFGFEIPNAPGK. . . . . . . . . . . . . . .
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Template Sequence  SGPF. . . . . . . . . DGTESEEGKRKVIAWLEEKGLGKGRVTYRLRDWLISRQR. YWGTPIPMVHCVVPVPEEELPVLLPDL
Template Known Secondary structure  SGGG.........TT
BTSS





.SSS






GGG







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   386... 390.........400.........410.........420........ .430.........440.........450.....
 
   250.........260.........270. ........280.........290.........300..
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . YFYVWLDAPIGYMGSFKNLCDK. RGDSVSFDEYWKKDSTAELYHFIGKDIVYFH
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Template Sequence  KDVEDISPLEAHPEFYETTCPKRDTDTMDTFFDSSWYYLRYTDPHNDRLPFDPEKANAWMPVD. . . . . QYIGGVEHAVLH
Template Known Secondary structure  S
STT

GGGG






B



TTTTSTT
SSSS


SBS.....

TT
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   460.........470.........480.........490.........500.........510.........520.. .......530....
 
   303. .....310..... ....320.........
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Query Sequence  SL. . . FWPAMLEGSNF. . . . RKPSNLFVHGYVTV. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  LLYSRFFTKFLHDLGMVKVEEPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEPTRIRLEIPESALSLEDVRKMGAELRPH
Template Known Secondary structure  TTS
S
S
SBS



TT

T
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STT

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   546...550.........560.........570.........580.........590.........600.........610.........620.....
 
   330.........340.........350.........360.........370.........380.........390.........400.
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Query Sequence  . . . . . . . . NGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFI
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Template Sequence  EDGTLHLWKPAVMSKSKGNGVMVGPFVKEQGADIARITILFAAP. PENEMVWTEEGVQGAWR. . FLNRIYRRVAEDREAL
Template Known Secondary structure  TTSS

TTTT


BS
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.TTS

..T
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   626...630.........640.........650.........660......... 670.........680...... ...690.........700..
 
   402.......410 .........420.........430.........440.........450.........460.........470.........
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Query Sequence  NKRFDGVLA. . SELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICS
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Template Sequence  LETSGVFQAEALEGKDRELYGKLHETLKKVTEDLEALRFNTAIAALMEFLNALYEYRKDRPV. . . . . . . . . . . . . . . . TP
Template Known Secondary structure  T





GGG

TT
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   703......710.........720.........730.........740.........750.........760.... ..
 
   480.........490.........500.........510.........520.....
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Query Sequence  MGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKV
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Template Sequence  VYRTAIRYYLQMLFPFAPHLAEELWHWFWPD. SLFEAGWPELDEKA
Template Known Secondary structure  TTTSTTT
SS.






TGG
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   767..770.........780.........790....... ..800.........810.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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