|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
. | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 50 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | S | I | G | I | D | S | G | S | T | A | T | K | G | I | L | L | A | . |
D | G | V | I | T | R | R | F | L | V | P | T | P | . |
. |
. |
. |
. |
. |
F | R | P | A | T | A | I | T | E | A | W | E | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | E | G | L | E | T | T | P | F | L | T | L |
Query Conservation |   |
  |   |
|
|
|
|   |
|   |
|   |   |
|   |
|   |   |   | . |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|
|
|
|
|   |   |
|
|   |
|
|
|
|
|   |   |
Template Sequence |   |
Y | Y | A | A | V | D | W | G | T | S | S | F | R | L | W | I | I | G | E | D | G | A | V | L | A | E | R | R | S | A | E | G | M | T | T | A | A | K | T | G | F | H | T | I | L | D | G | H | L | A | A | V | S | A | P | A | H | L | P | I | I | I | C | G | M | A | G | A | R | Q | G | W | K | E | A | G | Y | I | E | T |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T |
|
|  |  |  |  |  | G | G | G | S | T | T | S | S | S |
|
|
|  |  |  | S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . |
  |
  |   |
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | G | Y | G | R | Q | L | V | D | F | A | D | K | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | T | E | I | S | C | H | G | L | G | A | R | F | L | A | P | A | T | R | A | V | I | D | I | G | G | Q | D | S | K | V | I | Q | L | D | D | D | G | N | L | C | D | F |
Query Conservation |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
| . |   |   |
|   |
|   |   |
|
Template Sequence |   |
P | A | A | L | A | E | I | A | G | R | A | T | A | I | P | D | V | D | R | D | I | R | I | L | P | G | L | A | Q | R | D | R | R | H | P | D | V | M | R | G | E | E | T | Q | L | L | G | A | A | A | H | L | G | A | G | S | H | L | V | C | M | P | G | T | H | S | K | W | V | R | L | . |
A | D | D | R | V | E | G | F |
Template Known Secondary structure |   |
S |  |  | T | T |  |  |  |  | T |
|  |  |
| S | S | S | S | S |
|  |  |  |
|
|  |  |  |  |
|
| T | T | S |
|  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T | S |
| S | S |
|  |  |  |  |  |
| S | S | S |  |  |  |  |  |  | . |  | T | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . |  |
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
88 | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | |
. | 160 | . | . | . | . | . | . |
  |
  |   |
117 | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | M | N | D | K | C | A | A | G | T | G | R | F | L | E | V | I | S | R | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | S | V | E | Q | L | D | S | I | T | E | N | V | T | P | H | A | I | T | S | M | C | T | V | F | A | E | S | E | A | I | S | L | R | S | A | G | V | A | P | E | A | I | L | A | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . |   |
|   |
|
|
|
|
|
|
|   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   | . | . |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
S | T | F | M | T | G | E | L | F | D | T | I | A | R | H | T | I | L | S | H | A | V | A | E | A | D | T | F | A | A | G | S | A | A | F | T | D | A | V | S | R | T | R | E | N | P | A | L | A | T | N | L | L | F | S | . |
. |
V | R | A | G | Q | L | L | H | G | T | A | A | A | D | A | R | A | Q |
Template Known Secondary structure |   |
. | . | . | . | . |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | S | T | T |  |  |  |  | T | T |
| S |
|
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
167 | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
|
. | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
  |
  |   |
185 | . | . | . | . | 190 | . | . | |
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | I | N | A | M | A | R | R | . |
S | A | N | F | I | A | R | L | S | C | E | A | P | I | L | F | T | G | G | V | S | H | C | Q | K | F | A | R | M | L | E | S | H | L | R | M | P | V | N | T | H | P | D | A | Q | F | A | G | A | I | G | A | A | V | I | G | Q |
Query Conservation |   |
|   |   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|
| . |   |   |   |
|   |   |   |   |   |   | . |
|   |   |   |
|   |   |
|
|
|   |   |   |
|   |
Template Sequence |   |
L | S | G | T | L | I | G | L | E | I | A | G | A | L | A | G | S | G | S | V | D | G | V | C | L | V | G | S | G | G | L | G | T | L | Y | R | T | A | L | . |
E | S | Q | G | L | N | V | R | A | V | . |
D | A | D | E | A | V | R | A | G | L | S | A | A | A | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | . |  |  | T | T |
|  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
. | 280 | . | . | . | . | . | . | . | . | |
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . |
  |