|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
|
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | A | Y | S | I | G | I | D | S | G | S | T | A | T | K | G | I | L | L | A | . |
. |
D | G | V | I | T | R | R | F | L | V | P | T | P | F | R | P | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | A | I | T | E | A | W | E | T | L | R | E | G | L | E | T | T | P | F | L | T |
Query Conservation |   |
|   |   |   |
|
|
|
|   |
|   |
|   |   |
|   |
|   |   |   | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|
|   |
|
|
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
X | S | E | I | L | V | L | N | C | G | S | S | S | V | K | F | A | L | I | N | P | H | T | S | Q | S | L | V | T | G | L | A | E | N | I | A | T | K | N | C | K | V | V | F | K | A | E | H | K | I | V | K | Y | L | E | N | G | S | Y | K | D | V | F | E | X | L | K | D | F | L | V | E | N | K | H | L | E | K | I | V |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  | S | T | T | S | T | T |
|  |  |  |  |  | S | S | S |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| G | G | G |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
59 | 60 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
L | T | G | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | Q | L | V | D | F | A | D | K | Q | V | T | E | I | S | C | H | G | L | G | A | R | F | L | A | P | A | T | R | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|
|
|
|
|
|   |   |   |
|   |   |
|   |   |
|   |
|
|   |
Template Sequence |   |
A | I | G | H | R | V | V | H | G | G | Q | Y | F | S | K | S | V | L | I | N | A | D | S | L | E | K | I | K | A | C | I | A | L | A | P | L | H | N | P | A | H | I | E | G | I | R | F | C | Q | Q | I | F | P | E | L | P | Q | V | A | V | F | D | T | A | F | H | Q | T | X | P | S | Y | I | A | E | Y | A | I | P | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  | S |
|
| T | T | T |
| S | S |
|  |  |
| S |  |  |  |  |  |  |  |  |  | T | G | G | G | S | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T | S |
|  |  |  |  |  | T | T | G | G | G | G | G | S |
|  |  |  |  | S |
| S | S |
|  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
94 | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | I | D | I | G | G | Q | D | S | K | V | I | Q | L | D | D | D | G | N | L | C | D | F | L | M | N | D | K | C | A | A | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |
|
|   |   |   |
|   |   |
|
|
|   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|   |
|   | . |   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|   |
|
|
|
|   |
|
|
|
Template Sequence |   |
E | L | T | H | K | H | N | I | R | K | Y | G | A | H | G | T | S | H | K | Y | V | S | E | Q | A | A | K | I | L | T | Q | Q | K | A | N | V | I | V | A | H | L | G | N | G | C | S | I | T | A | V | . |
V | D | G | K | S | I | D | T | S | X | G | L | T | P | L | D | G | L | V | X | G | T | R | S | G | C | I | D | P |
Template Known Secondary structure |   |
 |  |  |  | T | S |
|
| S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| S | S |
|
|
|  |  |  |  |  |  | S | S | S |  |  |  |  |  |  | . |  | T | T |  |  |  |  |  | S |
|
| S | S | T | T | S | S | S |
|
| S | S |
|
|
| S |
|
| T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
. | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
  |
  |   |
127 | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | R | F | L | E | V | I | S | R | T | L | G | T | S | V | E | Q | L | D | S | I | T | E | N | V | T | P | H | A | I | T | S | M | C | T | V | F | A | E | S | . |
. |
. |
E | A | I | S | L | R | S | A | G | V | A | P | E | . |
A | I | L | A | G | V | I | N | A | M | A | R | R | S | A | N | F | I | A | R | L | S | C |
Query Conservation |   |
|   |   |
|
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   | . | . | . |   |
|   |   |   |   |   |   |
|   |   |   |   | . |
|
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   | . |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|   |   | . | . | . | . | . |
|
|
|   |
|   |
|
|   |
|
|   |
|   |
|   |   |   |   |   |   |
|
|   |   |
|   |
|
|   |
|   |
|   |
|
|
|   |
|   |
|
|
|   |   |
|   |
|
|
|
Template Sequence |   |
S | I | F | A | . |
Y | I | S | D | N | L | G | W | S | V | T | E | I | T | N | X | L | N | K | Q | . |
. |
. |
. |
. |
S | G | L | L | G | I | C | G | H | N | D | X | R | E | V | S | Q | L | A | A | K | G | D | S | L | A | K | L | A | I | E | I | F | S | H | R | V | A | K | F | V | A | S | Y | X | I | Y | F | N | K |
Template Known Secondary structure |   |
T |  |  |  | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  | S | . | . | . | . | . |
|  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
| S | S |
Template Predicted Secondary structure |   |
 |  |  |  | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
240 | . | . | . | |
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . |
  |
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | |
. | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | P | I | L | F | T | G | G | V | S | . |
H | C | Q | K | F | A | R | M | L | E | S | H | L | R |
Query Conservation |   |
  |   |   |
|
|
|   |
|
|   |
| . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|   |
Template Sequence |   |
L | D | A | L | V | F | T | G | G | I | G | E | N | A | A | N | I | R | K | N | I | I | S | K | L | A |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | G |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
314 | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . |
  |