|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
. | . | |
|
|
|
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . |
|
| . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
Query Sequence |   |
S | I | G | I | D | S | G | S | T | A | T | K | G | I | L | L | A | . |
D | G | . |
. |
. |
. |
V | I | T | R | R | F | L | V | P | T | P | F | R | P | A | T | A | I | T | E | A | W | E | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | E | G | L | E | T | T | P | F | L | T | L | T | G | Y | . |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|
|
|
|   |
|   |
|   |   |
|   |
|   |   |   | . |   |
| . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|   |   |
|   |
Template Sequence |   |
F | L | A | L | D | L | G | G | T | N | Y | R | V | L | S | V | T | L | E | G | G | K | S | P | R | I | Q | E | R | T | Y | C | I | P | A | E | K | M | S | G | S | G | T | E | L | F | K | Y | I | A | E | T | L | A | D | F | L | E | N | N | G | M | K | D | K | K | F | D | L | G | F | T | F | S | F | P | C | V | Q | K |
Template Known Secondary structure |   |
 |  |  |  |  |  | S | S | S | S |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| T | T | T | T | T | S | B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S | S |
|  |  |  |  |  |  |  |
| S |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
63 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | Q | L | V | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | A | D | K | Q | V | T | E | I | S | C | H | G | L | G | A | R | F | L | A | P | A | T | R | A | V | I | D | I | G | G | Q | D | S | K | V | I | Q | L | D | . |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |
|   |   |
|   | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |
|   |   |
|   |
|
|   |
|
|
|
|
|   |   |   |   |
|   |
|   |
|
|   |   |
|
|   |   |
|
|   |
|   |   |   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |
Template Sequence |   |
G | L | T | H | A | T | L | V | R | W | T | K | G | F | S | A | D | G | V | E | G | H | N | V | A | E | L | L | Q | T | E | L | D | K | R | E | L | N | V | K | C | V | A | V | V | N | D | T | V | G | T | L | A | S | C | A | L | E | D | P | K | C | A | V | G | L | I | V | G | T | G | T | N | V | A | Y | I | E | D | S |
Template Known Secondary structure |   |
T | T | T |  |  |  |  |
|
|
|
| T | T |
|
|
| B | T |
| T | T | S | B |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |  |  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
109 | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | D | G | N | L | C | D | F | L | M | N | D | K | C | A | A | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | G | R | F | L | E | V | I | S | R | T | L | G | T | S | V | E | Q | L | D | S | I | T | E |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|   |
|
|   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |
|   |
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |   |   |
|
|   |
Template Sequence |   |
S | K | V | E | L | M | D | G | V | K | E | P | E | V | V | I | N | T | E | W | G | A | F | G | E | K | G | E | L | D | C | W | R | T | Q | F | D | K | S | M | D | I | D | S | L | H | P | G | K | Q | L | Y | E | K | M | V | S | G | M | Y | L | G | E | L | V | R | H | I | I | V | Y | L | V | E | Q | K | I | L | F | R |
Template Known Secondary structure |   |
T | T |
| G | G | G |
| S |
| S | S | S |  |  |  |  |  |
|
| G | G | G | T | T | T | T | S | T | T | T | T | T |
|
|  |  |  |  |  |  |  |  | T | S | S | S | T | T | S |
| T | T |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | G | G |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
243 | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
  |
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
N | V | T | P | H | A | I | T | S | M | C | T | V | F | A | E | S | E | A | I | S | L | R | S | A | G | V | A | P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | I | L | A | G | V | I | N | A | M | A | R | R | S | A | N | F | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
A |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |
| . | . |   |
|   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |   |   |
|   |   |
|
|
|   |
|   |
|
|   |
|
|
|
|   |   |   |
Template Sequence |   |
G | D | L | P | E | R | L | K | V | R | N | S | L | . |
. |
L | T | R | Y | L | T | D | V | E | R | D | P | A | H | L | L | Y | N | T | H | Y | M | L | T | D | D | L | H | V | P | V | V | E | P | I | D | N | R | I | V | R | Y | A | C | E | M | V | V | K | R | A | A | Y | L | A | G | A | G | I | A | C | I | L | R | R |
Template Known Secondary structure |   |
G |
|
|
| S | G | G | G | S | T | T |
| S | . | . |
| T | T |  |  |  |  |  | T | T |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  | T | S |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
322 | . | . | . | . | . | . | . | 330 | . | . | . | . | |
|
. | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
  |
  |   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
. | . | . | . | . | 220 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | L | S | C | E | A | P | I | L | F | T | G | G | V | S | H | . |
C | Q | K | F | A | R | M | L | E | S | H | L | . |
. |
. |
. |
. |
. |
R | M | P | V | N | T | H | P | D | A | Q | F | A | G | A | I | G | A | A | V | I | G |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   | . |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|
|
| . |   |
|
|
|
|   |
|
Template Sequence |   |
I | N | R | S | E | V | T | V | G | V | D | G | S | L | Y | K | F | H | P | K | F | C | E | R | M | T | D | M | V | D | K | L | K | P | K | N | T | R | F | C | L | R | L | S | E | D | G | S | G | . |
K | G | A | A | A | I | A |
Template Known Secondary structure |   |
 |
|
| S |  |  |  |  |  |  |  | S |  |  |  |  |  |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | S |
| T | T |
|  |  |  |  |  |  |
| T | T |  |  |  | . |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  | . |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
397 | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | |
. | . | . | . | 450 | . | . |
  |