Return to main results Retrieve Phyre Job Id

Job DescriptionP64426
Confidence94.82%DateThu Jan 5 12:08:13 GMT 2012
Rank265Aligned Residues238
% Identity16%Templatec3lpgA_
PDB info PDB header:hydrolase/hydrolase inhibitorChain: A: PDB Molecule:beta-glucuronidase; PDBTitle: structure of e. coli beta-glucuronidase bound with a novel, potent2 inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,3 2-dihydroquinolin-3-yl)methyl)urea
Resolution2.42 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   88.90.........100.........110.........120.........130.........140.........150.........160.......
Predicted Secondary structure 




































Query SS confidence 















































































Query Sequence  QQAMIDKLDHLQRLGINTVFFQVKPDGTALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWFNPYRVSV
Query Conservation 
      

 
   
 


  


  






   
 
  


  
  
  


   
 











 
      
Alig confidence 






























............................









..








Template Conservation         
   
  
 
 

           ............................
 


 



..  
      
Template Sequence  NVLXVHDHALXDWIGANSYRTSHYPYAEEXL. . . . . . . . . . . . . . . . . . . . . . . . . . . . DWADEHGIVV. . IDETAAVGF
Template Known Secondary structure  T


TTS


............................T
..
S
B

Template Predicted Secondary structure 









............................


..





Template SS confidence 















































































   308.310.........320.........330........ .340........ .350.......
 
   168.170.........180.........190.........200.........210.........220.........230.........240.......
Predicted Secondary structure 















































Query SS confidence 















































































Query Sequence  NTKPGTIRELNSTLSQQPASVYVQHRDWIRTSGDRFVLDPGIPEVQDWITSIVAEVVSRYPVDGVQFDDYFYTESPGSRL
Query Conservation                                       


  



  
   
 


  









 


       
Alig confidence 


















..................























.................

Template Conservation                     ..................    
              
 
 
.................

Template Sequence  NLSLGIGFEAGNKPKELYS. . . . . . . . . . . . . . . . . . EEAVNGETQQAHLQAIKELIARDK. . . . . . . . . . . . . . . . . NH
Template Known Secondary structure 
S



SSS




S
SSB..................TTTB
T.................T
Template Predicted Secondary structure 


















..................





.................

Template SS confidence 















































































   358.360.........370...... ...380.........390.........400 ..
 
   248.250.........260.........270.........280.........290.........300.........310.........320.......
Predicted Secondary structure 
































Query SS confidence 















































































Query Sequence  NDNETYRKYGGAFASKADWRRNNTQQLIAKVSHTIKSIKPGVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRW
Query Conservation   
   
  
  
      


  
  

  
   

  

 
   


 
   
    
 

       
     
   
Alig confidence 

















.....
























...............













...
Template Conservation 



 
   

       .....           

  



 
   
...............              ...
Template Sequence  PSVVXWSIANEPDTRPQG. . . . . AREYFAPLAEATRKLDPTRPITCVN. . . . . . . . . . . . . . . VXFCDAHTDTISDL. . .
Template Known Secondary structure  TT




ST.....
SSS
B...............
TTS
TTT
SSGGG...
Template Predicted Secondary structure 











.....







...............













...
Template SS confidence 















































































   403......410.........420 .........430.........440..... ....450.........
 
   328.330.........340.........350.........360..... ....370... ......380.........390.........400.
Predicted Secondary structure 
















....

..
















Query SS confidence 





































. . . .







. .



























Query Sequence  VEQGLLDYIAPQIYWPFSRSAARYDVLAKWWADVVKPT. . . . RTRLYIGI. . AFYKVGEPSKIEPDWMINGGVPELKKQL
Query Conservation     
 

 
 

 
                
       ....   

 
 ..  
                   

  

Alig confidence  .....
































....







..



























Template Conservation  ..... 

     
 
                            
 
 

 
               

  

       
Template Sequence  . . . . . FDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSXYTDXWSEEYQCAWLDXYH
Template Known Secondary structure  .....SSS

BTTTBSTT









TT


TT

TTS
Template Predicted Secondary structure  .....





































Template SS confidence 















































































   460.........470.........480.........490.........500.........510.........520.........530....
 
   402.......410........
Predicted Secondary structure 





Query SS confidence 
















Query Sequence  DLNDAVPEISGTILFRE
Query Conservation     
      
   
  
Alig confidence 
















Template Conservation            
   
  
Template Sequence  RVFDRVSAVVGEQVWNF
Template Known Secondary structure  TT
TTS
Template Predicted Secondary structure 




Template SS confidence 
















   535....540.........550.
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions