|   |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | K | I | L | P | W | S | D | L | M | T | G | K | I | G | E | N | P | G | Y | D | P | L | Q | F | M | L | D | E | A | H | K | R | G | M | K | V | H | A | W | F | N | P | Y | R | V | S | V | N | T | K | P | G | T | I | R | E | L | N | S | T | L | S | Q | Q | P | A | S | V | Y | V | Q | H | R | D | W | I | R | T | S |
Query Conservation |   |
|   |   |   |
|   |
|   |   |
|
|
|   |   |
|   |   |
|   |   |
|
|
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
S | S | I | S | I | F | E | Y | H | I | A | P | N | G | D | I | A | N | Q | L | N | D | . |
A | A | A | I | E | T | T | W | Q | R | R | V | T | P | L | A | T | I | T | N | L | T | S | G | G | F | S | T | E | I | V | H | Q | V | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  | B |
| T | T | S |
| B |
|
|
|
| S |
| . |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
|  |  | T | T |  |  |
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
| . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
126 | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | |
. | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | D | R | F | V | L | D | P | G | I | P | E | V | Q | D | W | I | T | S | I | V | A | E | V | V | S | R | Y | P | V | D | G | V | Q | F | D | D | Y | F | Y | T | E | S | P | G | S | R | L | N | D | N | E | T | Y | R | K | Y | G | G | A | F | A | S | K | A | D | W | R | R | N | N | T | Q | Q | L | I | A | K | V | S |
Query Conservation |   |
  |   |   |   |   |
|
|
|   |   |
|
|
|
|   |   |
|   |   |   |
|   |
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |
|
|
|   |   |
|   |   |
|
|   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |
|
|
|
|
|
|
| . |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |   |
|
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
N | N | P | T | A | R | T | N | L | V | N | N | I | Y | D | L | V | S | T | R | G | Y | G | G | V | T | I | D | F | . |
E | Q | V | S | A | A | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | D | L | F | T | G | F | L | R | Q | L | R |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |
| . |
| S |
|
| G | G | G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . |
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
183 | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 220 | . | . | . | . | . | . | . | . | . | 230 |
  |
  |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 350 | |
|
|
. |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
|
Query Sequence |   |
H | T | I | K | S | I | K | P | G | V | E | F | G | V | S | P | A | G | V | W | R | N | R | S | H | D | P | L | G | S | D | T | R | G | A | A | A | Y | D | E | S | Y | A | D | T | R | R | W | V | E | Q | G | L | L | D | Y | I | A | P | Q | I | Y | . |
. |
. |
. |
. |
W | P | F | S | R | S | A | A | R | . |
. |
. |
Y |
Query Conservation |   |
  |   |
|
|   |   |
|
|   |
|   |   |   |
|
|
|   |
|   |   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |
|   |
|
|   |
| . | . | . | . | . |   |   |   |   |   |   |   |   |   | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|
|
|   |
|   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
Template Sequence |   |
D | R | L | Q | A | G | G | Y | V | L | T | I | A | V | P | A | . |
. |
K | T | S | D | N | I | P | W | L | R | G | Y | D | Y | G | G | I | G | A | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | N | Y | M | F | I | M | A | Y | D | W | H | H | A | G | S | E | P | G | P | V | A | P | I | T | E | I |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
| . | . |
| S |
| S |
|
| G | G | G | T | T |
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S |  |  |  |  |  |
|
|
| S | S |
| T | T | S |
| S |
|
| S | S |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
231 | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
|
. | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
  |
  |   |
352 | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 380 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
D | V | L | A | K | W | W | A | D | V | V | K | P | T | R | T | R | L | Y | I | G | I | A | F | Y | K | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | E | P | S | K | I | E | P | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |
|
|   |   | . | . |
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
R | R | T | I | E | F | T | I | A | Q | V | P | S | R | . |
. |
K | I | I | I | G | V | P | L | Y | G | Y | D | W | I | I | P | Y | Q | P | G | T | V | A | S | A | I | S | N | Q | N | A | I | E | R | A | M | R | Y | Q | A | P | I | Q | Y | S | A | E | Y | Q | S | P | F | F | R | Y | S | D | Q | Q | G | R | T | H | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | T | S |
| G | G | . | . | G |  |  |  |  |
|
| S |
|  |  |  |  |  | S | S |
|
| T | T |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  | T | T | T | T |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
294 | . | . | . | . | . | 300 | . | . | . | . | . | . | . | |
|
. | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . |
  |
  |   |
389 | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | I | N | G | G | V | P | E | L | K | K | Q | L | D | L | N | D | A | V | P | E | I | S | G | T | I | L | F | R |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   | . |
|   |
|
|   |
|
|   |
Template Sequence |   |
V | W | F | E | G | V | R | S | M | S | R | K | M | Q | I | V | R | E | Y | R | . |
L | Q | A | I | G | A | W | Q |
Template Known Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . |
| S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
372 | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | |
. | . | . | . | . | . | . | . |
  |