|   |
3 | . | . | . | . | . | . | |
|
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
 |  |  |  |
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
L | H | A | Q | A | K | H | . |
. |
G | K | P | G | L | P | W | L | V | F | L | H | G | F | S | G | D | C | H | E | W | Q | E | V | G | E | A | F | . |
. |
. |
. |
. |
. |
. |
. |
A | D | Y | S | R | L | Y | V | D | L | P | G | H | G | G | S | A | A | I | S | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D |
Query Conservation |   |
|
|   |   |   |   |   | . | . |
|   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . |   |   |   |   |
|
|   |   |
|
|   |
|   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | A | Y | K | S | W | G | R | M | N | V | S | R | D | N | C | V | I | V | C | H | T | L | T | S | S | A | H | V | T | S | W | W | P | T | L | F | G | Q | G | R | A | F | D | T | S | R | Y | F | I | I | C | L | N | Y | L | G | S | P | F | G | S | A | G | P | C | S | P | D | P | D | P | Y | G | A | K | F | P | R | T |
Template Known Secondary structure |   |
 |  |  |  |  |  | S |
|
|
| T | T | S |
|
|  |  |  |  |  |
|
| T | T |
|
| S |
| G | G | G | T | S | G | G | G | B | S | T | T | S | S | B |
| T | T | T |
|  |  |  |  |  |
|
| T | T |
| S | S | S | S | S | S | T | T | S |
|
|
|
|
|
| G | G | G |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
37 | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . |
  |
  |   |
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
G | F | D | D | V | T | D | L | L | R | K | T | L | V | S | Y | N | I | L | D | F | W | L | V | G | Y | S | L | G | G | R | V | A | M | M | A | A | C | Q | G | L | A | G | L | C | G | V | I | V | E | G | G | H | P | G | L | Q | N | A | E | Q | R | A | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |
|
|
|
|
|   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | I | R | D | D | V | R | I | H | R | Q | V | L | D | R | L | G | V | R | Q | I | A | A | V | V | G | A | M | G | G | M | H | T | L | E | W | A | F | F | G | P | E | Y | V | R | K | I | V | P | I | A | T | S | C | R | Q | S | G | W | C | A | A | W | F | E | T | Q | R | Q | C | I | Y | D | D | P | K | Y | L | D | G |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | G | G | G |
| T | T | T | B |
|
|  |  |  | B | S |
|
| S | B |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T | S | G | G | G |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
122 | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . |
  |
  |   |
|
|
|
|
|
|
|
|
124 | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 190 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
R | Q | R | S | D | R | Q | W | V | Q | R | F | L | T | E | P | L | T | A | V | F | A | D | W | Y | Q | Q | P | V | F | A | S | L | N | D | D | Q | R | R | E | L | V | A | L | R | S | N | N | N | G | A | T | L | A | A | M | L | E | A | T | S | L | . |
. |
. |
. |
. |
A | V | Q | P | D |
Query Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | Y | D | V | D | D | Q | P | V | R | G | L | E | T | A | R | K | I | A | N | L | T | Y | K | S | K | P | A | M | D | E | R | F | H | M | Q | P | I | E | A | V | S | S | Y | L | R | Y | Q | A | Q | K | F | A | A | S | F | D | A | N | C | Y | I | A | M | T | L | K | F | D | T | H | D | I | S | R | G | R | A | G | S |
Template Known Secondary structure |   |
T |
|
| T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  | S | B |
|
| B | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  |  |  |  | G | G | G |
| B | T | T | T | T | T |
| S | S |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . |
  |
  |   |
191 | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
220 | . | . | . | . | . | . | . | . | |
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | A | N | L | S | A | R | T | F | A | F | Y | Y | L | C | G | E | R | D | S | K | F | R | A | L | A | A | E | . |
. |
. |
. |
. |
. |
L | A | A | D | C | H | V | I | P | . |
R | A | G | H | N | A | H | R | E | N | P | A | G | V | I | A | S | L | A | Q | I | L | R |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   | . |   |   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|   |   |
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |
|
|   |
Template Sequence |   |
I | P | E | A | L | A | M | I | T | Q | P | A | L | I | I | C | A | R | S | D | G | L | Y | S | F | D | E | H | V | E | M | G | R | S | I | P | N | S | R | L | C | V | V | D | T | N | E | G | H | D | F | F | V | M | E | A | D | K | V | N | D | A | V | R | G | F | L | D |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|
| S |
|  |  |  |  |  |
| T | T |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  | S | T | T |  |  |  |  |  |
|
|
| S |
|
| T | T |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
314 | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . |
  |