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Job DescriptionP37355
Confidence99.37%DateThu Jan 5 11:55:32 GMT 2012
Rank161Aligned Residues190
% Identity18%Templatec2g5tA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   15....20...... ...30.........40.........50... ......60.........70.... ..
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Query Sequence  PWLVFLHGFSGD. . . . . . . CHEWQEVGEAFADYSRLYVDLPGHGGS. . . . . . . . . AAISVDGFDDVTDLLRKTLVS. . YN
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Template Sequence  PLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVD
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   541........550.........560.........570.........580.........590.........600.........610.........620
 
   77..80.........90.........100.........110.........120.........130.........140.........150......
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Query Sequence  ILDFWLVGYSLGGRVAMMAACQGLAGLCGVIVEGGHPGLQNAEQRAERQRSDRQWVQRFLTEPLTAVFADWYQQPVFASL
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Template Sequence  NKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR. . . . . . . . . . . . . . . . . . . . . . WEYYDSVYTERYMGLPTPED
Template Known Secondary structure  TTS




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   621........630.........640.........650........ .660.........670........
 
   157..160.........170.........180.........190......... 200.........210......... 220.....
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Query Sequence  NDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSART. FAFYYLCGERDSKFRALAAE. . . . . . . . . . LAADCH
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Template Sequence  NLDHYRNS. . . . . . . . . . . . . . . . . . . . . . . . . TVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAM
Template Known Secondary structure  TT.........................
SGGGGGGGGGSTT
SSS
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   679680...... ...690.........700.........710.........720.........730...
 
   226...230.... .....240.........250.
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Query Sequence  VIPRAGHNA. HRENPAGVIASLAQILR
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Template Sequence  WYTDEDHGIASSTAHQHIYTHMSHFIK
Template Known Secondary structure  TT

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   734.....740.........750.........760
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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