|   |
18 | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | |
|
|
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | N | R | F | F | F | M | S | P | Y | R | S | F | T | T | S | G | C | F | A | R | F | . |
. |
. |
D | E | P | A | V | N | G | D | S | P | D | S | P | F | Q | Q | K | L | A | A | L | F | A | D | A | K | A | Q | G | I | K | N | P | V | M | V | G | A | I | P | F | D | P | R | Q | P | S | S | L | Y | I | P | E | S | W |
Query Conservation |   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | T | Q | E | R | E | A | M | F | F | G | G | L | F | A | Y | D | L | V | A | G | F | E | A | L | P | H | L | E | A | G | N | N | C | P | D | Y | C | F | Y | L | A | E | T | L | M | V | I | D | H | Q | K | K | S | . |
. |
. |
. |
T | R | I | Q | A | S | L | F | T | A | S | D | R | E | K | Q | R | L | N | A | R | L |
Template Known Secondary structure |   |
| T | T |
| T | T | S | S |  |  |  |  |  |  |
| G | G | G | G | G | G | T | S |
|
|
|
|
|
|
| S | S | S |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  | . | . | . | . |  |  |  |  |  |  |  |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | |
|
|
|
. | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . |
  |
  |   |
95 | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | S | F | S | R | Q | E | K | Q | A | S | A | R | R | F | T | R | S | Q | S | L | N | V | V | E | R | Q | A | I | P | E | Q | T | T | F | E | Q | M | V | A | R | A | A | A | L | T | A | T | P | Q | V | D | K | V | V | L | S | R | L | I | D | I | T | T | D | A | A | I | D | S | G | V | L | L | E | R | L | I | A | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|
|
|   |   |   |   |   |   |   |   | . | . | . |   |
|   |   |   |
|   |   |
|
|   |   |
Template Sequence |   |
A | Y | L | S | Q | Q | L | T | Q | P | A | P | P | . |
. |
L | P | V | T | P | V | P | D | M | R | C | E | C | N | Q | S | D | D | A | F | G | A | V | V | R | Q | L | Q | K | A | I | R | A | G | E | I | F | Q | V | V | P | S | R | R | F | S | L | P | C | P | . |
. |
. |
S | P | L | A | A | Y | Y | V | L | K | K | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | S |
|
|
|
| . | . |
|
|
|
|
|
| T | T |
|
|
|  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |
|
|  |  |  |  |  |  |  |
| S | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
213 | . | . | . | . | . | . | 220 | . | . | . | . | . | |
|
. | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | |
|
|
. | . | . | . | 280 | . | . | . | . | . | . | . |
  |
  |   |
175 | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
. | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | P | V | S | Y | N | F | H | V | P | L | A | D | G | G | V | L | L | G | A | S | P | E | L | L | L | R | K | D | G | . |
. |
E | R | F | S | S | I | P | L | A | G | S | A | R | R | Q | P | D | E | . |
. |
. |
. |
. |
. |
V | L | D | R | E | A | G | N | R | L | L | A | S | E | K | D | R | H | E | H | E | L | V | T |
Query Conservation |   |
  |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |   |   |
| . | . |   |   |
|   |
|   |
|
|
|
|
|   |   |
|   |   |   |   | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |   |   |   |   |   |   |   | . |   |   |   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|
|   |   |
|
|   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |
|   |
|
|   |
|
|
|   |
|
|
|
Template Sequence |   |
N | P | S | P | Y | M | F | F | M | Q | D | N | D | . |
F | T | L | F | G | A | S | P | E | S | S | L | K | Y | D | A | A | S | R | Q | I | E | I | Y | P | I | A | G | T | R | P | R | G | R | R | A | D | G | T | L | D | R | D | L | D | S | R | I | E | L | D | M | R | T | D | H | K | E | L | S | E | H | L | M | L | V |
Template Known Secondary structure |   |
S |
|
| S |  |  |  |  |  |  |
| S | S | . |
|  |  |  |  |  |  | S | S |
| S |  |  |  |  | T | T | T | T |  |  |  |  |
|
|  |  |  |  |  |  |
|
| B |
| T | T | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
288 | . | 290 | . | . | . | . | . | . | . | . | . | 300 | |
. | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . |
  |
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | |
|
. | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | A | M | K | E | V | L | R | E | R | S | . |
. |
S | E | L | H | V | P | S | S | P | Q | L | I | T | T | P | T | L | W | H | L | A | T | P | F | E | G | K | A | N | S | Q | E | N | A | L | T | L | A | C | L | L | H | P | T | P | A | L | S | G | F | P | H | Q | A | A | T | Q | V | I | A | E | L | E | P | F | D | R |
Query Conservation |   |
|   |
|   |   |   |
|   |   |   |   | . | . |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|
|   |
|
|
|   |   |
|
|
|   |
|   |   |   |   |   |
|
|   |   |   |   |
|   |
|
|
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |   |
|
|   |   |   |
|
Template Sequence |   |
D | L | A | R | N | D | L | A | R | I | C | T | P | G | S | R | Y | V | A | D | L | T | K | V | D | R | Y | S | Y | V | M | H | L | V | S | R | V | V | G | E | L | R | H | D | L | D | A | L | H | A | Y | R | A | C | M | N | M | G | T | L | S | G | A | P | K | V | R | A | M | Q | L | I | A | D | A | E | G | Q | R | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | B |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  | B |
| T | T |
|
|  |  |  |  |  |  |  |  |
| S |
| G | G | G | S |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
367 | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . |
  |
  |   |
325 | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | F | G | G | I | V | G | W | C | D | S | E | G | N | G | E | W | V | V | T | I | R | C | A | K | L | R | E | N | Q | V | R | L | F | A | G | A | G | I | V | P | A | S | S | P | L | G | E | W | R | E | T | G | V | K | L | S | T | M | L | N | V | F |
Query Conservation |   |
|   |
|
|
|   |
|
|   |
|   |   |   |
|   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |   |
|   |
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|   |
|
|   |   |   |   |   |
|   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |
|
|   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|
|
Template Sequence |   |
G | S | Y | G | G | A | V | G | Y | F | T | A | H | G | D | L | D | T | C | I | V | I | R | S | A | L | V | E | N | G | I | A | T | V | Q | A | G | A | G | I | V | L | D | S | V | P | Q | S | E | A | D | E | T | R | N | K | A | R | A | V | L | R | A | I |
Template Known Secondary structure |   |
T | T | T | T | S |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |
|
| S |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
| B |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
447 | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 |
  |