|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
. | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
Query Sequence |   |
M | Q | A | L | L | L | E | Q | Q | D | G | K | T | L | A | S | V | Q | T | L | D | E | S | R | L | P | E | G | D | V | T | V | D | V | H | W | S | S | L | N | Y | K | D | A | L | A | I | T | G | K | G | K | I | I | R | N | F | P | M | I | P | G | I | D | F | A | G | T | V | R | T | S | E | . |
. |
D | P | R | F | H |
Query Conservation |   |
|
|
|   |
|   |   |   |   |
|   |
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|   |   |   |   |
|   |   | . | . |
|   |
|   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |
Template Sequence |   |
M | K | A | A | V | V | H | A | Y | G | A | P | . |
. |
L | R | I | E | E | V | K | V | P | L | P | G | P | G | Q | V | L | V | K | I | E | A | S | G | V | C | H | T | D | L | H | A | A | E | G | D | W | P | V | K | P | P | L | P | F | I | P | G | H | E | G | V | G | Y | V | A | A | V | G | S | G | V | T | R | V | K |
Template Known Secondary structure |   |
 |
| B |  |  | B |
| B | T | T | B |
| . | . |
|  |  |
|
|  |  |
|
|
|
|
| T | T |
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  | T | T |
| S | S | S |
|
|
| S | S | B |
|
|
| S |
|  |  |  |  |  |  |  |  |
| T | T |
|
| S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
| . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | |
|
. | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . |
Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | Q | E | V | L | L | T | G | W | G | V | G | E | N | H | W | G | G | L | A | E | Q | A | R | V | K | G | D | W | L | V | A | M | P | Q | G | L | D | A | R | K | A | M | I | I | G | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | G | F | T | A | M | L | C | V | M | A | L | E | D | A |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | G | D | R | V | G | I | P | W | L | Y | T | A | C | G | C | C | E | H | C | L | T | G | W | E | T | L | C | E | S | Q | Q | N | T | G | Y | S | V | N | G | G | Y | A | E | Y | V | L | A | D | P | N | Y | V | G | I | L | P | K | N | V | E | F | A | E | I | A | P | I | L | C | A | G | V | T | V | Y | K | G | L | K |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |
| S |  |  |  |
|
| S | S | S | T | T | T | T | T | T |
| G | G | G |
| T | T |
|  |  | B | T | T | T | B |
|
| S | S | B | S |  |  |  |  |
| T | T | T | S |  |  |
|
| T | T | S |
|  |  |  |  | G | G | G | G | T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
142 | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
|
|
210 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | R | P | Q | D | G | E | I | V | V | T | G | A | S | G | G | V | G | S | T | A | V | A | L | L | H | K | L | G | Y | Q | V | V | A | V | S | G | R | E | S | T | H | E | Y | L | K | S | L | G | A | S | R | V | L | P | R | D | E | F | A | E | S | R | P | L | E | K | . |
. |
. |
Q | V | W | A | G | A | I | D | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | T | N | A | R | P | G | Q | W | V | A | I | S | G | I | G | G | L | G | H | V | A | V | Q | Y | A | R | A | M | G | L | H | V | A | A | I | D | I | D | D | A | K | L | E | L | A | R | K | L | G | A | S | L | T | V | N | A | R | Q | E | D | P | V | E | A | I | Q | R | D | I | G | G | A | H | G | V | L | V | T | A |
Template Known Secondary structure |   |
 |  | T |
|
| T | T | S |  |  |  |  |  |
|
| S | T | T |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  | T | T | T | S |
|  |  |  |  |  |  |  |  | T | S | S |  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
  |
  |   |
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | G | D | K | V | L | A | K | V | L | A | Q | M | N | Y | G | G | C | V | A | A | C | G | L | A | G | G | F | T | L | P | T | T | V | M | P | F | I | L | R | N | V | R | L | Q | G | V | D | S | V | M | T | P | P | E | R | R | A | Q | A | W | Q | R | L | V | A | D | L | P | E | S | F | Y | T | Q | A | A | K | E | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |
Template Sequence |   |
V | S | N | S | A | F | G | Q | A | I | G | M | A | R | R | G | G | T | I | A | L | V | G | L | P | . |
P | G | D | F | P | T | P | I | F | D | V | V | L | K | G | L | H | I | A | G | S | I | V | G | T | . |
. |
. |
. |
. |
. |
R | A | D | L | Q | E | A | L | D | F | A | G | E | G | L | V | K | A | T | I | H | P | G |
Template Known Secondary structure |   |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
| S |
|
|
|
|
|  |  |  |  |  |  | T | T |
|  |  |  |  |
|
| S |
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
  |
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | L | S | E | A | P | N | F | A | E | A | I | I | N | N | Q | I | Q | G | R | T | L | V | K | V |
Query Conservation |   |
  |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|   |
|
Template Sequence |   |
K | L | D | D | I | N | Q | I | L | D | Q | M | R | A | G | Q | I | E | G | R | I | V | L | E | M |
Template Known Secondary structure |   |
| G | G | G |  |  |  |  |  |  |  |  |  | T | T |
|
| S | S |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . |
  |