|   |
145 | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | N | G | T | T | S | A | V | V | V | D | E | G | G | E | L | L | V | Y | P | G | G | E | A | S | N | C | E | I | N | Q | G | G | V | F | M | L | A | G | K | A | S | D | T | L | L | A | G | G | T | M | N | N | L | G | G | E | D | S | D | T | I | V | E | N | G | S | I | Y | R | L | G | T | D | G | L | Q | L | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | T | F | K | A | E | N | F | Q | I | K | G | G | S | A | V | V | S | R | N | V | S | S | I | E | G | N | W | T | V | S | N | N | A | N | A | T | F | G | V | V | P | N | Q | Q | N | T | I | C | T | R | S | D | W | T | G | L | T | T | C | Q | K | V | D | L | T | D | T | K | V | I | N | S | I | P | K | T | Q | I | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |
|
|
| T | T | S |  |  |  |  |  |  |  |
| T | T | T |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | S |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . |
  |
  |   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | S | G | K | T | Q | N | L | S | V | N | V | G | G | R | A | E | V | H | A | G | T | L | E | N | A | V | I | Q | G | G | T | V | I | L | L | S | P | T | S | A | D | E | N | F | V | V | E | E | D | R | A | P | V | E | L | T | G | S | V | A | L | L | D | G | A | S | M | I | I | G | Y | G | A | E | L | Q | Q | S | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
G | S | I | N | L | T | D | N | A | T | A | N | V | K | G | L | A | K | L | N | G | N | V | T | L | T | N | H | S | Q | F | T | L | S | N | N | A | T | Q | I | G | N | I | R | L | S | D | N | S | T | A | T | V | D | N | A | N | L | N | G | N | V | H | L | T | D | S | A | Q | F | S | L | K | N | S | H | F | S | H | Q |
Template Known Secondary structure |   |
S |
|  |  |  |
| T | T |
|  |  |  |  |  | S | S |  |  |  |
| S |
|  |  |  |
| T | T |
|  |  |  |  |  | T | T |
|  |  |  | S |
|  |  |  |
| T | T |
|  |  |  |  |  | S | S |  |  |  | S |
|  |  |  |
| T | T |
|  |  |  |  |  | S |
|  |  |
| S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . |
  |
  |   |
305 | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | |
. | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  | . |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | T | V | Q | Q | G | G | V | L | I | L | D | G | S | T | V | K | G | D | S | V | T | F | I | V | G | N | I | N | L | N | G | G | K | L | W | L | I | T | D | A | A | T | H | V | Q | L | K | V | K | R | . |
L | R | G | E | G | A | I | C | L | Q | T | S | A | K | E | I | S | P | D | F | I | N | V | K | G | E | V | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   | . |
|
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |
Template Sequence |   |
I | Q | G | D | K | G | T | T | V | T | L | . |
E | N | A | T | W | T | M | P | S | D | T | T | L | Q | N | L | T | L | N | N | S | T | I | T | L | N | S | A | Y | S | R | F | N | T | L | T | V | N | G | K | L | S | G | Q | G | T | F | Q | F | T | S | S | L | F | G | Y | K | S | D | K | L | K | L | S | N | D | A | E |
Template Known Secondary structure |   |
 |  |  |
| T | T |
|  |  |  |  | . |  | S |
|  |  |  |
|
| S |
|  |  |  | S |  |  |  |  |  |  |  |  |  |  | S |
| G | G | G |
|
|
|
|  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |
|  |  |  |  |
| T | T |
|
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  | . |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
810 | . | . | . | . | . | . | . | . | . | 820 | |
. | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . |
  |
  |   |
384 | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | D | I | H | V | E | I | T | D | A | S | R | Q | T | L | C | N | A | L | K | L | Q | P | D | E | D | G | I |
Query Conservation |   |
|   |   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |
|   |
|   |
|   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |
Template Sequence |   |
G | D | Y | I | L | S | V | R | N | T | G | K | E | P | E | T | L | E | Q | L | T | L | V | E | S | K | D | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| S |
|
|
| S | S |
|
|
|  |  |  |  |  |  | S | S | S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
912 | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . |
  |