|   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | P | A | L | L | T | G | N | T | I | V | I | K | P | S | E | F | T | P | N | N | A | I | A | F | A | K | I | V | D | E | I | G | L | P | R | G | V | F | N | L | V | L | G | R | G | E | T | V | G | Q | E | L | A | G | N | P | K | V | A | M | V | S | M | T | G | S | V | S | A | G | E | K | I | M | A | T | A | A | K |
Query Conservation |   |
  |   |
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |
|
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |
|
|
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|
|
|
|   | . | . | . | . |   |   |
|
|
|   | . | . | . | . | . |
|
|   |   |
|   |   |   |   |
|   |
|   | . |
|   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   | . | . |
Template Sequence |   |
F | A | S | D | H | E | S | G | K | L | L | V | L | P | T | V | W | D | T | W | S | A | G | L | V | . |
. |
. |
. |
E | E | A | G | F | S | . |
. |
. |
. |
. |
G | L | T | I | G | S | H | P | V | A | D | A | T | . |
G | S | S | D | G | E | N | X | N | F | A | D | Y | X | A | V | V | K | K | I | T | S | A | V | . |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  | T |
|
|
|  |  |
|
|  |  | S | S |  |  |  |  |  |  |  | . | . | . | . |  |  | T | T |
| S | . | . | . | . | . |
|  |  |  |
|  |  |  |  |  |  |  | T | . | T |
|
| T | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . |  |  |
|
|
|
| . | . | . | . | . |  |  |  |  |  |
|  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
11 | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | |
|
|
|
. | . | . | . | 40 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 50 | . | . | . | . | |
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | |
|
  |
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | |
|
|
. | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | I | T | K | V | C | L | E | L | G | G | K | A | P | A | I | V | M | D | D | A | D | L | E | L | A | V | K | A | I | V | D | S | R | V | I | N | S | G | Q | V | C | N | C | A | E | R | V | Y | V | Q | K | G | I | Y | . |
. |
. |
D | Q | F | V | N | R | L | G | E | A | M | Q | A | V | Q | F | G | N | P | A | E | R |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |
|
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |
|   |
|   |   |   |
|   | . | . | . |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|
|   |
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | I | P | V | S | V | D | V | E | S | G | Y | G | L | S | P | A | D | L | I | A | Q | I | L | E | A | G | A | V | G | I | N | V | E | D | V | V | H | S | E | G | K | R | V | R | E | A | Q | E | H | A | D | Y | I | A | A | A | R | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | S | S |
|  |  |  |  |
| T | T |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S |  |  | G | G | G | T | T |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
  |
  |   |
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | |
|
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
N | D | I | A | M | G | P | L | I | N | A | A | A | L | E | R | V | E | Q | K | V | A | R | A | V | E | E | G | A | R | V | A | F | G | G | K | A | V | E | G | K | G | Y | Y | Y | P | P | T | L | L | L | D | V | R | Q | E | M | S | I | M | H | E | E | T | F | G | P | V | L | P | V | V | A | F | D | T | L | . |
. |
. |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | A | D | V | A | G | V | D | V | V | I | N | G | R | T | D | A | V | K | L | G |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
138 | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
398 | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | |
|
|
. | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
E | D | A | I | S | M | A | N | D | S | D | Y | G | L | T | S | S | I | Y | . |
. |
. |
T | Q | N | L | N | V | A | M | K | A | I | K | G | L | K | F | G | E | T | Y | I | N | R | E | N | F | E | A | M | Q | G | F |
Query Conservation |   |
. | . | . | . | . | . | . | . |   |
|
|
|   |   |   |
|   |   |   |   |
|
|   |
|   |
|   | . | . | . |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|   |
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | D | V | F | E | D | P | X | V | E | A | I | K | R | I | K | L | X | E | Q | A | G | A | R | S | V | Y | P | V | G | L | S | T | A | E | Q | V | E | R | L | V | D | A | V | S | . |
V | P | V | N | I | T | A | H | P | V | D | G | H | G | A | G |
Template Known Secondary structure |   |
T | T | T | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |
|
|
|
| S |  |  |  |  |  |  |  |  | T | T |
| S | . | S |
| B |  |  |  |
| B | T | T | T | B | B | T | T | B |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | |
. | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
  |