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Job DescriptionP00582
Confidence100.00%DateThu Jan 5 10:56:46 GMT 2012
Rank2Aligned Residues600
% Identity100%Templatec2kzzA_
PDB info PDB header:transferase/dnaChain: A: PDB Molecule:protein (dna polymerase i); PDBTitle: klenow fragment with normal substrate and zinc only
Resolution2.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   325....330.........340.........350.........360.........370.........380.........390.........400....
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Query Sequence  ISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALEL
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Template Conservation 
    
  
   
 
      
     
  



  
      
  



                              
Template Sequence  ISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALEL
Template Known Secondary structure 

TTTS

STTSSSS
S
TTT

TT



STT





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   325....330.........340.........350.........360.........370.........380.........390.........400....
 
   405....410.........420.........430.........440.........450.........460.........470.........480....
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Query Sequence  LKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQL
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Template Conservation 

  


  
 

 

 


   
   

 
     

 


 

       

  
    
     
            
Template Sequence  LKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQL
Template Known Secondary structure  T
TTS
SSTTT





TTSS

SS






SSTT

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   405....410.........420.........430.........440.........450.........460.........470.........480....
 
   485....490.........500.........510.........520.........530.........540.........550.........560....
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Query Sequence  TFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLA
Query Conservation         
    

  

  
  
   
   
     
      

 

  

  

  

 

   
            
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Template Conservation              

  
    
 
   
   
            

 
    
  

  

 

 
 
            
Template Sequence  TFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLA
Template Known Secondary structure 
GGGS
TTS
T
B
B
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   485....490.........500.........510.........520.........530.........540.........550.........560....
 
   565....570.........580.........590.........600.........610.........620.........630.........640....
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Query Sequence  ELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKL
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Template Conservation 

   
    
  

  
  

   
   


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Template Sequence  ELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTP. . . . STSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKL
Template Known Secondary structure  SSS


S
TTTTSTTTSS
S





....TTT

TTT
STTTTG
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....





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   565....570.........580.........590.........600... ......610.........620.........630.........640
 
   645....650.........660.........670.........680.........690.........700.........710.........720....
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Query Sequence  PLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLL
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Template Sequence  PLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLL
Template Known Secondary structure  GGG

TTTSSB

SS

SSS

SS
GGGS
SSSTBB

TTTTTT
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   645....650.........660.........670.........680.........690.........700.........710.........720....
 
   725....730.........740.........750.........760.........770.........780.........790.........800....
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Query Sequence  TAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLEYMER
Query Conservation   

  
 


   
   

   
 

   
  

 
 

  

 
   

  



  

   
       
 
      
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Template Conservation       
 
 
   
          
    
  

    
  

 
   
      
  

           
        
Template Sequence  TAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLEYMER
Template Known Secondary structure  TT

TT

GGG

TT

T

TTTST
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   725....730.........740.........750.........760.........770.........780.........790.........800....
 
   805....810.........820.........830.........840.........850.........860.........870.........880....
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Query Sequence  TRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDEL
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Template Conservation      
   
 
 
  

                   
 
 
  


 



 
 
                    



 
Template Sequence  TRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDEL
Template Known Secondary structure  S
TT


TTTT
SS

STT
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   805....810.........820.........830.........840.........850.........860.........870.........880....
 
   885....890.........900.........910.........920........
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Query Sequence  VFEVHKDDVDAVAKQIHQLMENCTRLDVPLLVEVGSGENWDQAH
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Template Conservation                     
       


      
  
 
 
Template Sequence  VFEVHKDDVDAVAKQIHQLMENCTRLDVPLLVEVGSGENWDQAH
Template Known Secondary structure  TTTSS
SSS


SB
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   885....890.........900.........910.........920........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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