|   |
376 | . | . | . | 380 | . | . | . | . | . | |
|
|
|
. | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | R | I | D | I | A | A | N | I | G | . |
. |
. |
. |
T | A | L | E | A | P | G | A | F | A | N | G | A | E | G | V | G | L | F | R | T | E | M | L | Y | M | D | R | D | S | A | P | D | E | Q | E | Q | F | E | A | Y | Q | Q | V | L | L | A | A | G | D | K | P | I | I | F | R | T | M | D | I | G | G | D | K | S | I |
Query Conservation |   |
  |   |
|   |
|   |
|
|
|   | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |
|   |
|
|
|
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . |
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |
|   |   |
|
|   |
|
|   |
|
|   | . | . | . | . | . | . |
|
|
|   |
|
|
|   |   |
|   |   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |
|   | . |   |
|
|   |
| . | . | . | . |
Template Sequence |   |
R | R | T | S | I | I | G | T | I | G | P | K | T | N | N | P | E | T | L | V | A | L | R | K | A | G | L | N | I | V | . |
. |
. |
. |
. |
. |
R | M | N | F | S | H | G | S | Y | E | Y | H | K | S | V | I | D | N | A | R | K | S | E | E | L | Y | P | G | R | P | L | A | I | A | . |
L | D | T | K | G | . |
. |
. |
. |
Template Known Secondary structure |   |
|
| S |  |  |  |  |  |
|
| T | T | T |
| S |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  | . | . | . | . | . | . |  |  |  | T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S |
|
| B |
|  | . |  |  |
|
|
| . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . |  |
|
|
|
| . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
. | . | . | . | . | |
|
|
|
  |
  |   |
452 | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | Y | L | N | I | P | Q | E | E | N | P | F | L | G | Y | R | A | V | R | I | Y | P | E | F | A | G | L | F | R | T | Q | L | R | A | I | L | R | A | A | S | F | G | N | A | Q | L | M | I | P | M | V | H | S | L | D | Q | I | L | W | V | K | G | E | I | Q | K | A | I | V | E | L | K | R | D | G | L | R | H | A | E |
Query Conservation |   |
  |
|
|   |   |   |   |
|   |
|
|
|
|
|   |
|
|
|
|   |   |
|   |   |
|   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |
|
|   |
|
|
|
|   |   |
|
|   |   |   |
|
|   |   |
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|
|
|   |
|   |
|
|
|
|   |
|
|   |
|
|   |   |
|
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | A | L | S | E | K | D | K | E | D | L | R | F | G | V | K | N | G | V | H | M | V | F | A | S | F | I | R | T | A | N | D | V | L | T | I | R | E | V | L | G | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | G | K |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |
|
| T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |
| G | . | . | . | . | . | . | . | . | . | . | . | G | G | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | |
|
|
|
|
|
|
|
|
|
|
. | . | . |
  |
  |   |
532 | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | I | T | L | G | I | M | V | E | V | P | S | V | C | Y | I | I | D | H | F | C | D | E | V | D | F | F | S | I | G | S | N | D | M | T | Q | Y | L | Y | A | V | D | R | N | N | P | R | V | S | P | L | Y | N | P | I | T | P | S | F | L | R | M | L | Q | Q | I | V | T | T | A | H | Q | R | G | K | W | V | G | I | C |
Query Conservation |   |
  |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |
|   |   |
|
|   |
|
|
|   |   |
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|   |
|
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |   |   |
|
|   |
|
|   |   |
|   |   |   |
|
|
|
|
|   |
|
Template Sequence |   |
D | V | K | I | I | V | K | I | E | N | Q | Q | G | V | N | N | F | D | E | I | L | K | V | T | D | G | V | M | V | A | R | G | D | L | G | I | E | I | P | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | V | L | A | V | Q | K | K | L | I | A | K | S | N | L | A | G | K | P | V | I | C | A |
Template Known Secondary structure |   |
T | S |
|
|  |  |  |  |
| S |  |  |  |  | T | T |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
  |
  |   |
612 | . | . |
Predicted Secondary structure |   |
|
|
|
Query SS confidence |   |
|
|
|
Query Sequence |   |
G | E | L |
Query Conservation |   |
|
|   |
Alig confidence |   |
|
|
|
Template Conservation |   |
|
|   |
Template Sequence |   |
T | Q | M |
Template Known Secondary structure |   |
S | S | S |
Template Predicted Secondary structure |   |
|
|  |
Template SS confidence |   |
|
|
|
  |   |
298 | . | 300 |
  |