|   |
114 | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
. | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | G | Q | N | V | V | L | S | A | P | T | S | M | G | K | S | A | I | V | D | S | L | L | . |
. |
. |
G | M | G | T | L | K | R | L | V | L | V | V | P | T | V | A | L | A | D | E | T | R | R | R | L | Q | E | R | F | G | D | R | Y | Q | I | I | H | H | S | S | Q | V | C | H | S | D | Q | A | V | Y | V | L | T | Q |
Query Conservation |   |
  |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |
| . | . | . |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|
|   |   |   |
|
|
|
|
|
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
Template Sequence |   |
K | K | R | L | T | I | M | D | L | H | P | G | A | G | K | T | K | R | I | L | P | S | I | V | R | E | A | L | K | R | R | L | R | T | L | I | L | A | P | T | R | V | V | A | A | E | M | E | E | A | L | R | G | L | P | I | R | . |
. |
Y | Q | T | P | A | V | K | S | D | H | T | G | R | E | I | V | D | L | M | C | H |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |
|
|
| T | T | T |
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
|  |  | . | . |  |
|
| T | T |
| S |
|
|
|
|
| S | S |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
  |
  |   |
191 | . | . | . | . | . | . | |
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | R | V | N | E | R | D | . |
. |
. |
. |
D | I | V | D | I | D | L | F | V | I | D | E | F | Y | K | L | A | F | R | Q | L | K | S | G | D | I | D | H | Q | D | E | R | V | I | E | L | N | I | A | L | S | K | L | L | K | V | S | R | Q | F | Y | L | T | G | P | F | V | N | S | I | R | G | L | E | K | L | G | Y | P |
Query Conservation |   |
|
|
|   |   |   |   | . | . | . | . |   |   |   |   |
|   |
|   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |   |
Template Sequence |   |
A | T | F | T | T | R | L | L | S | S | T | R | V | P | N | Y | N | L | I | V | M | D | E | A | H | F | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | P | C | S | V | A | A | R | G | Y | I | S | T | R | V | E | M | G | E | A | A | A | I | F | M | T | A | T | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| S |
|
|
|
|
| S |  |  |  |  |  | S | T | T |
|
| . | . | . | . | . | . | . | . | . | . | . | . | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |
| S | S |
| . | . | . | . | . | . | . | . | . | . | . | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. |
  |
  |   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | T | F | V | S | T | D | F | N | T | V | A | L | D | V | K | T | F | G | I | K | A | N | D | D | K | A | K | L | K | A | L | G | E | I | A | H | A | C | V | D | A | T | I | I | Y | C | K | S | P | T | V | A | G | L | V | A | R | E | L | I | R | L | G | H | G | T | P | T | E | N | P | H | V | D | W | V | S | E | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . |   |
|   |   |
|
|
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
G | S | T | D | P | F | P | Q | S | N | S | P | I | E | D | I | E | R | E | I | P | E | R | S | W | N | T | G | F | D | W | I | T | D | Y | . |
. |
. |
. |
Q | G | K | T | V | W | F | V | P | S | I | K | A | G | N | D | I | A | N | C | L | R | K | S | G | K | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T |
|
|
| S | S |
|
|
| S | S |
|  |  |  |  |  |
|
|
|
| S | S |
|
|
| S | S |
|  |  |  |  |  |
| . | . | . | . |
| S |
|  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | |
|
|
|
. | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
347 | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 410 | . | . | . | |
|
|
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
| . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
F | D | A | D | W | D | Y | T | V | A | L | R | N | G | I | G | L | H | F | G | A | L | P | R | A | L | Q | Q | Y | T | A | D | Q | F | N | A | G | K | L | R | F | L | L | C | T | S | T | I | I | E | G | V | N | T | I | A | K | N | V | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | Y | D | N | R | D | G | . |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |
|   |
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|   |   |
|
| . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|
|
|   |
|   |
|
|
|
|   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | I | Q | L | S | R | K | T | . |
. |
. |
. |
F | D | T | E | Y | P | K | T | K | L | T | D | W | D | F | V | V | T | T | D | I | S | E | M | G | A | N | F | R | A | G | R | V | I | D | P | R | R | C | L | K | P | V | I | L | T | D | G | P | E | R | V | I | L |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
| T | T | T | . | . | . | . |  |  |  |  | T |  |  |  |  |  | S |
|
| S |  |  |  |  |
| G | G | G | G | T | T |
|
|
|
|
| S |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | S | S | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|  |  |  | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
382 | . | . | . | . | . | . | . | |
|
|
|
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . |
  |
  |   |
|
|
414 | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
T | R | S | I | D | K | F | T | H | G | N | I | K | G | R | A | G | R | M | G | V | H | F | V | G | K | I | F | C | L | E | E | I | P |
Query Conservation |   |
. | . |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|
|   |
|
|   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | G | P | I | P | V | T | P | A | S | A | A | Q | R | R | G | R | I | G | R | N | P | A | . |
Q | E | D | D | Q | Y | V | F | S | G | D | P |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | T | S | S |
| S |
|
| . | S | S |
|  |  |  |  |  |
| S |
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|
|
|
|  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
444 | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | |
. | . | . | 470 | . | . | . | . | . | . | . | . |
  |