|   |
175 | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | Y | K | A | L | G | H | P | V | M | I | N | Y | L | K | Q | L | G | I | T | A | L | E | L | L | P | V | A | Q | F | A | S | E | P | R | L | Q | R | M | G | L | S | N | Y | W | G | Y | N | P | V | A | M | F | A | L | H | P | A | Y | A | C | S | P | E | T | A | L | D | E | F | R | D | A | I | K | A | L | H | K | A |
Query Conservation |   |
|
|   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
| . | . |   |   |   |
|
|
|
| . |   |
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|
|   | . | . | . | . | . | . | . | . | . |
|
|
|
|
|   |
|   |   |   |
|
|
|
|
|
|
| . | . | . | . | . |   |
|   |
|   |   |
|
|   |
|
|
|   |   |
Template Sequence |   |
N | F | G | D | V | . |
. |
I | D | N | L | W | Y | F | . |
D | L | G | V | S | H | L | Y | L | S | P | V | L | M | A | S | P | G | S | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
H | G | Y | D | V | I | D | H | S | R | I | N | D | E | L | G | G | . |
. |
. |
. |
. |
E | K | E | Y | R | R | L | I | E | T | A | H | T | I |
Template Known Secondary structure |   |
|  |  |  |  | . | . |  |  | T | T | T | T |
| . |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |
| T | T |
| S | . | . | . | . | . | . | . | . | . | S |
|
| S |  |  |  |  |  |  |  |
| T | T | T | T |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  | . | . |  |  |  |
|
|  |  | . |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
15 | . | . | . | . | |
|
20 | . | . | . | . | . | . | |
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
  |
  |   |
255 | . | . | . | . | 260 | . | . | . | . | . | . | |
|
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
G | I | E | V | I | L | D | I | V | L | N | H | . |
. |
S | A | E | L | D | L | D | G | P | L | F | S | L | R | G | I | D | N | R | S | Y | Y | W | I | R | E | D | G | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|   |
|
|
|
|
|
|   |
|
| . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |
|   |   |
|
| . |
|   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|
Template Sequence |   |
G | L | G | I | I | Q | D | I | V | P | N | H | M | A | V | N | S | L | N | W | R | L | M | D | V | . |
L | M | G | S | Y | Y | T | Y | F | D | F | F | P | E | D | D | K | I | R | L | P | I | L | G | E | D | L | D | T | V | I | S | K | G | L | L | K | I | V | K | D | G | D | E | Y | F | L | E | Y | F | K | W | K | L |
Template Known Secondary structure |   |
T |
|  |  |  |  |  |  |
|
| S |  |  |  |
|
| T | T |
|  |  |  |  |  |  | . |
|
|
|
|
| G | G | G | B |
| B |
| T | T |
| S | S |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| S | S |
|  |  |  |  |  | T | T |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | |
. | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
296 | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | H | N | W | T | G | C | G | N | T | L | N | L | S | H | P | A | V | V | D | Y | A | S | A | C | L | R | Y | W | V | E | T | C | H | V | D | G | F | R | F | D | L | A | A | V | M | G | R | T | P | E | F | R | Q | D |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|
|
|   |   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
|
|   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |
|
|
|   |   |
|
|   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |   |
|
|
|
|   |   |
|
|   |   |   |
|   |
|
|
|   | . |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|
| . | . | . | . | . | . |
Template Sequence |   |
P | L | T | E | V | G | N | D | I | Y | D | T | L | Q | K | Q | N | Y | T | L | M | S | W | K | N | P | P | S | Y | R | R | F | F | D | V | N | T | L | I | G | V | N | V | E | D | H | V | F | Q | E | S | H | S | I | L | D | L | . |
D | V | D | G | Y | R | I | D | H | I | D | G | L | Y | D | P | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |
| S |
|
|
| S | S |  |  |  |  |  | T | T | S | S |  |  |  |  |  | T | T | S |
|
| S | B |
|  |  | T | T |  |  |  |  |  |  | B |
|
|
|
|  |  |  |  |  |  | T |
|
| T | T | S | . |
|
| S |  |  |  |  | T | T | G | G | G |
| S |
|  | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
. | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
|
|
|
|
  |
  |   |
351 | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | P | L | F | T | A | I | Q | N | C | P | V | L | S | Q | V | K | L | I | A | E | P | W | D | I | A | P | G | G | Y | Q | V | G | N | F | P | P | L | F | A | E | W | N | D | H | F | R | D | A | A | R | R | F | W | L | H | Y | D | L | P | L | G | A | F | A | G | R | F | A | A |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
|
|   |   |   |   |   | . | . | . |   |
|
|
|
|
|
|
|   |   |   |
|   |
|
| . | . | . | . |
|   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
Template Sequence |   |
E | K | Y | I | N | D | L | R | S | I | I | K | N | . |
. |
. |
I | I | I | V | E | K | I | L | G | F | Q | E | E | L | K | . |
. |
. |
. |
L | N | S | D | G | T | T | G | Y | D | F | L | N | Y | S | N | L | L | F | N | F | N | Q | E | I | M | D | S | I | Y | E | N | F | T | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|  |  |  |
|
|
|
|
| T | T |
|
|
|
| . | . | . | . | S | S | S | S |  |  | S | S |  |  |  |  |  |  |  |  | G | G | G |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | |
|
|
|
. | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
  |