Job Description P08200 Confidence 100.00% Date Thu Jan 5 11:00:54 GMT 2012 Rank 27 Aligned Residues 364 % Identity 19% Template c2qfyE_ PDB info PDB header:oxidoreductase Chain: E: PDB Molecule:isocitrate dehydrogenase [nadp]; PDBTitle: crystal structure of saccharomyces cerevesiae mitochondrial nadp(+)-2 dependent isocitrate dehydrogenase in complex with a-ketoglutarate Resolution 2.10 Å

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		12	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	K	I	T	L	Q	N	G	K	L	N	V	P	E	N	P	I	I	P	Y	I	E	G	D	G	I	G	V	D	V	T	P	A	M	L	K	V	V	D	A	A	V	E	K	A	Y	K	G	E	R	K	I	S	W	M	E	I	Y	T	G	E	K	S	T	Q	V	Y	G	Q	D	V	W	L	P	A	E	T	L	D	L
Query Conservation
Alig confidence									.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.	.																						.	.
Template Conservation									.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.	.																						.	.
Template Sequence		S	K	I	K	V	K	Q	.	.	.	.	.	.	.	.	.	P	V	V	E	L	D	G	D	E	M	T	R	I	I	W	D	K	I	K	K	K	L	I	L	P	.	.	.	.	.	.	.	Y	L	D	V	D	L	K	Y	Y	D	L	S	V	E	S	R	D	A	T	S	D	.	.	K	I	T	Q	D	A	A	E	A
Template Known Secondary structure		T					S	S	.	.	.	.	.	.	.	.	.																						T	T	T	T	.	.	.	.	.	.	.	T											S							T	T	T	.	.
Template Predicted Secondary structure									.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.	.																						.	.
Template SS confidence
		3	.	.	.	.	.	.										10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.								.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.			.	.	.	.	60	.	.	.	.
		92	.	.	.	.	.	.	.	100	.	.	.	.	.	.										.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.
Predicted Secondary structure																	.	.	.	.	.	.	.	.	.
Query SS confidence																	.	.	.	.	.	.	.	.	.
Query Sequence		I	R	E	Y	R	V	A	I	K	G	P	L	T	T	P	.	.	.	.	.	.	.	.	.	V	G	G	G	I	R	S	L	N	V	A	L	R	Q	E	L	D	L	Y	I	C	L	R	P	V	R	Y	Y	Q	G	T	P	S	P	V	K	H	P	E	L	T	D	M	V	I	F	R	E	N	S	E	D	I	Y	A	G
Query Conservation																	.	.	.	.	.	.	.	.	.
Alig confidence																	.	.	.	.	.	.	.	.	.																											.														.
Template Conservation																																																				.														.
Template Sequence		I	K	K	Y	G	V	G	I	K	C	A	T	I	T	P	D	E	A	R	V	K	E	F	N	L	H	K	M	W	K	S	P	N	G	T	I	R	N	I	L	G	G	T	V	F	R	E	P	I	V	.	I	P	R	I	P	R	L	V	P	R	W	E	K	.	P	I	I	I	G	R	H	A	H	G	D	Q	Y	K	A
Template Known Secondary structure						S																		T	T		S	S															S									.		T	T	S			S	S	T	T			S	.									S	S	G	G	G	S
Template Predicted Secondary structure																																																				.														.
Template SS confidence
		65	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.		.	.	.	.	.	120	.	.	.	.	.	.	.		.	.	130	.	.	.	.	.	.	.	.	.	140	.	.
		163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.						.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
Predicted Secondary structure																					.	.	.	.	.
Query SS confidence																					.	.	.	.	.
Query Sequence		I	E	W	K	A	D	S	A	D	A	E	K	V	I	K	F	L	R	E	.	.	.	.	.	E	M	G	V	K	K	I	R	F	P	E	H	C	G	I	G	I	K	P	C	S	E	E	G	T	K	R	L	V	R	A	A	I	E	Y	A	I	A	N	D	R	D	S	V	T	L	V	H	K	G	N	I	M	K	F	T
Query Conservation																					.	.	.	.	.
Alig confidence																					.	.	.	.	.																																								.
Template Conservation																																																																	.
Template Sequence		T	D	T	L	I	P	G	P	G	S	L	E	L	V	Y	K	P	S	D	P	T	T	A	Q	P	Q	T	L	K	V	Y	D	Y	K	G	S	G	V	A	M	A	M	Y	N	T	D	E	S	I	E	G	F	A	H	S	S	F	K	L	A	I	D	K	.	K	L	N	L	F	L	S	T	K	N	T	I	L	K	K	Y
Template Known Secondary structure								S	S										S		T	T	T	S											S	S																												T	.	T									T	T	T	S	T	T
Template Predicted Secondary structure																																																																	.
Template SS confidence
		143	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.		.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.
		238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	G	A	F	K	D	W	G	Y	Q	L	A	R	E	E	F	G	G	E	L	I	D	G	G	P	W	L	K	V	K	N	P	N	T	G	K	E	I	V	I	K	D	V	I	A	D	A	F	L	Q	Q	I	L	L	R	P	A	E	Y	D	V	I	A	C	M	N	L	N	G	D	Y	I	S	D	A	L	A	A	Q	V
Query Conservation
Alig confidence																								.	.	.	.	.	.	.	.	.	.	.	.	.																									.
Template Conservation																								.	.	.	.	.	.	.	.	.	.	.	.	.																									.
Template Sequence		D	G	R	F	K	D	I	F	Q	E	V	Y	E	A	Q	Y	K	S	K	F	E	Q	.	.	.	.	.	.	.	.	.	.	.	.	.	L	G	I	H	Y	E	H	R	L	I	D	D	M	V	A	Q	M	I	K	S	K	G	G	F	.	I	M	A	L	K	N	Y	D	G	D	V	Q	S	D	I	V	A	Q	G	F
Template Known Secondary structure																	T							.	.	.	.	.	.	.	.	.	.	.	.	.		T																		S					.
Template Predicted Secondary structure																								.	.	.	.	.	.	.	.	.	.	.	.	.																									.
Template SS confidence
		222	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.														.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.		.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.
		318	.	320	.	.	.	.	.	.	.	.	.	330			.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.							.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.								.	.	.	.	.	.	.	.	380	.	.
Predicted Secondary structure															.	.																						.	.	.	.	.	.																					.	.	.	.	.	.	.
Query SS confidence															.	.																						.	.	.	.	.	.																					.	.	.	.	.	.	.
Query Sequence		G	G	I	G	I	A	P	G	A	N	I	G	D	.	.	E	C	A	L	F	E	A	T	H	G	T	A	P	K	Y	A	G	Q	D	K	V	.	.	.	.	.	.	N	P	G	S	I	I	L	S	A	E	M	M	L	R	H	M	G	W	T	E	.	.	.	.	.	.	.	A	A	D	L	I	V	K	G	M	E	G
Query Conservation															.	.																						.	.	.	.	.	.																					.	.	.	.	.	.	.
Alig confidence															.	.																						.	.	.	.	.	.																					.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	S	L	G	L	M	T	S	I	L	V	T	P	D	G	K	T	F	E	S	E	A	A	H	G	T	V	T	R	H	Y	R	K	Y	Q	K	G	E	E	T	S	T	N	S	I	A	S	I	F	A	W	S	R	G	L	L	K	R	G	E	L	D	N	T	P	A	L	C	K	F	A	N	I	L	E	S	A	T	L	N
Template Known Secondary structure		T		T	T	S								T	T	S									S											T	T	T																										T
Template Predicted Secondary structure
Template SS confidence
		288	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.
		383	.		.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.										.	.	.	.	.	.	410	.	.	.	.	.	.
Predicted Secondary structure				.																				.	.	.	.	.	.	.	.	.
Query SS confidence				.																				.	.	.	.	.	.	.	.	.
Query Sequence		A	I	.	N	A	K	T	V	T	Y	D	F	E	R	L	M	D	G	A	K	L	L	.	.	.	.	.	.	.	.	.	K	C	S	E	F	G	D	A	I	I	E	N	M
Query Conservation				.																				.	.	.	.	.	.	.	.	.
Alig confidence				.										.	.	.	.	.	.					.	.	.	.	.	.	.	.	.
Template Conservation														.	.	.	.	.	.
Template Sequence		T	V	Q	Q	D	G	I	M	T	K	D	L	.	.	.	.	.	.	A	L	A	C	G	N	N	E	R	S	A	Y	V	T	T	E	E	F	L	D	A	V	E	K	R	L
Template Known Secondary structure					T	S								.	.	.	.	.	.					T				G	G	G
Template Predicted Secondary structure														.	.	.	.	.	.
Template SS confidence
		368	.	370	.	.	.	.	.	.	.	.	.							380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.