Job Description P08200 Confidence 100.00% Date Thu Jan 5 11:00:54 GMT 2012 Rank 16 Aligned Residues 404 % Identity 57% Template c2iv0A_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: thermal stability of isocitrate dehydrogenase from2 archaeoglobus fulgidus studied by crystal structure3 analysis and engineering of chimers Resolution 2.5 Å

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		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	V	V	V	P	A	Q	G	K	K	I	T	L	Q	N	G	K	L	N	V	P	E	N	P	I	I	P	Y	I	E	G	D	G	I	G	V	D	V	T	P	A	M	L	K	V	V	D	A	A	V	E	K	A	Y	K	G	E	R	K	I	S	W	M	E	I	Y	T	G	E	K	S	T	Q	V	Y	G	Q	D	V	W
Query Conservation
Alig confidence																																																							.	.	.																						.	.
Template Conservation																																																							.	.	.																						.	.
Template Sequence		K	V	K	P	P	E	N	G	E	K	I	R	Y	E	N	G	K	L	I	V	P	D	N	P	I	I	P	Y	F	E	G	D	G	I	G	K	D	V	V	P	A	A	I	R	V	L	D	A	A	A	D	K	I	.	.	.	G	K	E	V	V	W	F	Q	V	Y	A	G	E	D	A	Y	K	L	Y	G	N	.	.	Y
Template Known Secondary structure		S					S	S		B						T	T						S	S	B								S	T	T																				.	.	.	T											S								S		.	.	S
Template Predicted Secondary structure																																																							.	.	.																						.	.
Template SS confidence
		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.				.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.			.
		84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	P	A	E	T	L	D	L	I	R	E	Y	R	V	A	I	K	G	P	L	T	T	P	V	G	G	G	I	R	S	L	N	V	A	L	R	Q	E	L	D	L	Y	I	C	L	R	P	V	R	Y	Y	Q	G	T	P	S	P	V	K	H	P	E	L	T	D	M	V	I	F	R	E	N	S	E	D	I	Y	A	G	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	P	D	D	T	L	N	A	I	K	E	F	R	V	A	L	K	G	P	L	T	T	P	V	G	G	G	Y	R	S	L	N	V	T	I	R	Q	V	L	D	L	Y	A	N	V	R	P	V	Y	Y	L	K	G	V	P	S	P	I	K	H	P	E	K	V	N	F	V	I	F	R	E	N	T	E	D	V	Y	A	G	I
Template Known Secondary structure		S																							S	S	S	S	S	S										T	T												T	T	S			S	S	S		G	G	G										S	S	S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	W	K	A	D	S	A	D	A	E	K	V	I	K	F	L	R	E	E	M	G	V	K	K	I	R	F	P	E	H	C	G	I	G	I	K	P	C	S	E	E	G	T	K	R	L	V	R	A	A	I	E	Y	A	I	A	N	D	R	D	S	V	T	L	V	H	K	G	N	I	M	K	F	T	E	G	A	F	K	D
Query Conservation
Alig confidence																							.	.	.
Template Conservation																							.	.	.
Template Sequence		E	W	P	R	G	S	E	E	A	L	K	L	I	R	F	L	K	N	E	F	G	.	.	.	V	T	I	R	E	D	S	G	I	G	I	K	P	I	S	E	F	A	T	K	R	L	V	R	M	A	I	R	Y	A	I	E	N	N	R	K	S	V	T	L	V	H	K	G	N	I	M	K	Y	T	E	G	A	F	R	D
Template Known Secondary structure					T	T																	.	.	.					T	T																											T	T		S								T	T	T		T	T	T
Template Predicted Secondary structure																							.	.	.
Template SS confidence
		160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180				.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
		244	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.		.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.
Predicted Secondary structure																															.
Query SS confidence																															.
Query Sequence		W	G	Y	Q	L	A	R	E	E	F	G	G	E	L	I	D	G	G	P	W	L	K	V	K	N	P	N	T	G	.	K	E	I	V	I	K	D	V	I	A	D	A	F	L	Q	Q	I	L	L	R	P	A	E	Y	D	V	I	A	C	M	N	L	N	G	D	Y	I	S	D	A	L	A	A	Q	V	G	G	I	G	I
Query Conservation																															.
Alig confidence																															.
Template Conservation
Template Sequence		W	G	Y	E	V	A	K	Q	E	F	G	E	Y	C	I	T	E	D	E	L	W	D	K	Y	G	G	K	Q	P	E	G	K	I	V	V	K	D	R	I	A	D	N	M	F	Q	Q	I	L	T	R	T	D	E	Y	D	V	I	A	L	P	N	L	N	G	D	Y	L	S	D	A	A	A	A	L	I	G	G	L	G	I
Template Known Secondary structure											S	T	T	T												T	T				T	T									G	G	G								S	G	G	G																						T	T		G	G	G
Template Predicted Secondary structure
Template SS confidence
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
		323	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	P	G	A	N	I	G	D	E	C	A	L	F	E	A	T	H	G	T	A	P	K	Y	A	G	Q	D	K	V	N	P	G	S	I	I	L	S	A	E	M	M	L	R	H	M	G	W	T	E	A	A	D	L	I	V	K	G	M	E	G	A	I	N	A	K	T	V	T	Y	D	F	E	R	L	M	D	G	A	K	L
Query Conservation
Alig confidence																																																																														.
Template Conservation																																																																														.
Template Sequence		A	P	G	S	N	I	G	D	G	I	G	V	F	E	P	V	H	G	S	A	P	K	Y	A	G	Q	N	K	V	N	P	T	A	E	I	L	T	G	A	L	M	F	E	Y	I	G	W	K	D	A	S	E	M	I	K	K	A	V	E	M	T	I	S	S	G	I	V	T	Y	D	I	H	R	H	M	G	.	G	T	K
Template Known Secondary structure									T	T							S	S				S	T	T	T	T	S	S		S																T	T																		T	T												.	S
Template Predicted Secondary structure																																																																														.
Template SS confidence
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.		.	.	.
		403	.	.	.	.	.	.	410	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	K	C	S	E	F	G	D	A	I	I	E	N	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	G	T	R	E	F	A	E	A	V	V	E	N	L
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		396	.	.	.	400	.	.	.	.	.	.	.	.	.