|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | |
|
70 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  | . | . |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
Query Sequence |   |
N | G | K | K | L | Y | I | S | D | V | T | L | R | D | G | M | H | A | . |
I | R | H | Q | Y | S | L | E | N | V | R | Q | I | A | K | A | L | D | D | A | R | V | D | . |
. |
S | I | E | V | A | H | G | D | G | L | Q | G | S | S | F | N | Y | G | F | G | A | H | S | D | L | E | W | . |
. |
I | E | A | A | A | D | V |
Query Conservation |   |
  |   |
|   |
|   |
|   |
|   |
|
|
|
|
|   |
|   | . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   | . | . |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |
|
|
|
|
|
|
|   |
|
|
|   |
|   |
|   |   |   |   |
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |   |
|
|
|   | . | . | . | . | . |   |
|
|
|   |
|   |
|   |   |
|
|
|   |
|   |
|   |
|
|
|   |   |
|   |   |   |
Template Sequence |   |
K | Q | D | D | V | L | L | T | D | T | T | F | R | D | A | H | Q | S | L | L | A | T | R | V | R | T | K | D | M | I | N | I | A | S | K | T | A | D | V | F | K | D | G | F | S | L | E | M | . |
. |
. |
. |
. |
W | G | G | A | T | F | D | V | A | Y | N | F | L | K | E | N | P | W | E | R | L | E | R | L | R | K | A |
Template Known Secondary structure |   |
 |
|
| S | B |  |  |  |  |
| T | T | T |  |  |  |  |  |  | S | T | T |
|
|
|  |  |  |  |  |  | T |  |  |  |  |  |  |  | T | T | T | S | S |  |  |  |  | . | . | . | . | . |  |  | T | T |  |  |  |  |  |  |  | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
559 | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . |
  |
  |   |
77 | . | . | 80 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
V | K | H | A | K | I | A | T | L | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | G | I | G | T | I | H | D | L | K | N | A | W | Q | A | G | A | R | V | V | R | V | A | T | H | C | T | E | A | D | V | S | A | Q | H | I | Q | Y | A | R | E | L | G | M | D | T | V | G | F | L | M | . |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
Template Sequence |   |
I | P | N | V | L | F | Q | M | L | L | R | A | S | N | A | V | G | Y | K | N | Y | P | D | N | V | I | H | K | F | V | Q | E | S | A | K | A | G | I | D | V | F | R | I | F | D | S | L | N | W | V | D | Q | M | K | V | A | N | E | A | V | Q | E | A | G | K | I | S | E | G | T | I | C | Y | T | G | D | I | L | N | P |
Template Known Secondary structure |   |
|
| S | S |  |  |  |  |  |  | B | G | G | G | B | T | S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
|
| T | T |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
|
| S |
| T | T |
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
634 | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . |
  |
  |   |
|
139 | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
M | S | H | M | T | T | P | E | N | L | A | K | Q | A | K | L | M | E | G | Y | G | A | T | C | I | Y | V | V | D | S | G | G | A | M | N | M | S | D | I | R | D | R | F | R | A | L | K | A | E | L | K | P | E | T | Q | T | G | M | H | A | H | H | N | L | S | L | G | V | A | N | S | I | A | A | V | E | E | G | C |
Query Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|
|
|   |
|
|
|   |
|
|   |
|
|
|   |   |
|
|
|
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|
|
|   |
|   |
|
|
|
|   |
|   |
|   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |   | . | . |   |   |
|
|   |   |
|   |
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|
|
Template Sequence |   |
E | R | S | N | I | Y | T | L | E | Y | Y | V | K | L | A | K | E | L | E | R | E | G | F | H | I | L | A | I | K | D | M | A | G | L | L | K | P | K | A | A | Y | E | L | I | G | E | L | K | S | A | V | . |
. |
D | L | P | I | H | L | H | T | H | D | T | S | G | N | G | L | L | T | Y | K | Q | A | I | D | A | G | V |
Template Known Secondary structure |   |
T | T |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  | T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . |
| S |
|  |  |  |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
714 | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | |
|
. | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . |
  |
  |   |
218 | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
. | . | . | . | . | 290 |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
D | R | I | D | A | S | L | A | G | M | G | A | G | A | G | N | A | P | L | E | V | F | I | A | A | A | D | K | L | G | W | Q | H | G | T | D | L | Y | A | L | M | D | A | A | D | D | L | V | R | . |
. |
. |
. |
. |
. |
P | L | Q | D | R | P | V | R | V | D | R | E | T | L | A | L | G | Y | . |
A | G | V | Y | S | S |
Query Conservation |   |
  |   |
|
|   |
|
|   |
|
|
|
|
|
|
|
|   |   |   |
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |
|
|
Template Sequence |   |
D | I | I | D | T | A | V | A | S | M | S | G | L | T | S | Q | P | S | A | N | S | L | Y | Y | A | L | N | G | F | P | R | H | L | R | T | D | I | E | G | M | E | S | L | S | H | Y | W | S | T | V | R | T | Y | Y | S | D | F | E | S | D | I | K | S | P | N | T | E | I | Y | Q | H | E | M | P | G | G | Q | Y | S | N |
Template Known Secondary structure |   |
|  |  |  |  | B |
| G | G | G |
| S | T | T | S |
|
| B |  |  |  |  |  |  |  | T | T | T | S | S | S |
| B |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | G | G | G |
|
| S |
|
| S |
|
| T | T |  |  |  |  |
|
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
792 | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . |
  |
  |   |
291 | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | L | R | H | C | E | T | A | A | A | R | Y | G | L | S | A | . |
. |
. |
. |
. |
V | D | I | L | V | E | L | G | K | R | R | M | V | G | G | Q | E | D | M | I | V | D | V | A | L | D | L | R | N | N |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   |
|
|
|   |
|
|
|
|
|   |   |
|   |   |   |
|   |   |
Template Sequence |   |
L | S | Q | Q | A | K | S | L | G | L | G | E | R | F | D | E | V | K | D | M | Y | R | R | V | N | F | L | F | G | D | I | V | K | V | T | P | S | S | K | V | V | G | D | M | A | L | Y | M | V | Q | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | T | S | S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
874 | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . |
  |