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Job DescriptionP51020
Confidence100.00%DateThu Jan 5 12:04:49 GMT 2012
Rank16Aligned Residues261
% Identity22%Templatec2cw6B_
PDB info PDB header:lyaseChain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3......10.........20.........30.........40.........50.........60.........70.........80..
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Query Sequence  GKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSIEVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKI
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Template Sequence  PKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIETTSFVSPKW. . . . . . VPQMGDHTEVLKGIQKFPGINY
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   30.........40.........50.........60.........70.........80. ........90.........100...
 
   83......90.........100.........110..... ....120.........130.........140 ..
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Query Sequence  ATLLLPGIGTIHDLKNAWQAGARVVRVATHCTE. . . . . . . . . . . . . . ADVSAQHIQYARELGMDTVGFLMMS. . . . . . HM
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Template Sequence  PVL. . . . TPNLKGFEAAVAAGAKEVVIFGAASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGK
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   104.. ...110.........120.........130.........140.........150.........160.........170.........
 
   143......150.........160.........170.........180.........190.........200.........210.........220..
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Query Sequence  TTPENLAKQAKLMEGYGATCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCDRIDA
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Template Sequence  ISPAKVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEV. PLAALAVHCHDTYGQALANTLMALQMGVSVVDS
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   180.........190.........200.........210.........220..... ....230.........240.........250........
 
   223..... .230.........240.........250.........260.........270....
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Query Sequence  SLAGMG. . . . . . AGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVR
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Template Sequence  SVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSS
Template Known Secondary structure  BTTS



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B
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   259260.........270.........280.........290.........300.........310......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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