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Job DescriptionP25549
Confidence99.97%DateThu Jan 5 11:42:06 GMT 2012
Rank21Aligned Residues265
% Identity19%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   85....90.........100.........110.........120.........130... .. ....140.........150.......
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Query Sequence  KPNVVVFLLDDVGWMDVGFNGGGVAVGNPTPDIDAVASQGLILTSAYSQ. PS. SSPTRATILTGQYSIHHGILMP. . . . .
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Template Sequence  RPPLIIFSVDGFRASYMKKGSK. . . . . . VMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP
Template Known Secondary structure  S

T

GGGGGS
TT......TSS
S


SS
S
S
S


SST
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   162.......170.........180... ......190.........200.........210.........220.........230.....
 
   158.160.........170.........180.........190.........200.........210.........220........
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Query Sequence  . . . . . . . . . PMYGQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYTEWRDVHVNPE
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Template Sequence  VFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTF. . . . . . . . . . FWSVSIPHER. . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TTT
SSSSGGG
TTS

S

TTT

B


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TTS
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   236...240.........250.........260.........270... ......280...
 
   229230.........240.........250.........260.........270.........280.........290.........300........
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Query Sequence  VALSPDRSEYIKQLPFSKDDVHAVRGGEQQAIADITPKYMEDLDQRWMDYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYP
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RILTILQWL. SLPDNERPSVYAFYSEQPDF. . . S
Template Known Secondary structure  ..............................................T.TS
TTT

S...
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   284.....290.. .......300.........310.. .
 
   309310.........320.........330.........340.........350.........360
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Query Sequence  NAKYAGSSPARTSYGDCMVEMNDVFANLYKTLEKNGQLDNTLIVFTSDNGPE. . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  GHKYGPFGPE. . . MTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLG
Template Known Secondary structure 
TT
GG...GTT
TTT
S




SSSGGGT
S

TT
BS
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   314.....320... ......330.........340.........350.........360.........370.........380.........390
 
   361........370.........380........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AEVPPHGRTPFRGAKGSTWEGGVRVPTF
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Template Sequence  RIRAKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPFQGDHGFDNKVNSMQTVFV
Template Known Secondary structure 


TTSS
STT

GGGS
GGG


SSTTS
S
TT
S





S
TT
GGG
B
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   391........400.........410.........420.........430.........440.........450.........460.........470
 
   389390.........400.........410......... 420.........430.........440.........450
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Query Sequence  VYWKGMIQPRKSDGIVDLADLFPTALDLAGH. PGAKVANLVPKTTFIDGVDQTSFFLGTNGQS
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Template Sequence  GYGPT. FKYRTKVPPFENIELYNVMCDLLGLKPAPNNGT. . . . . . . . . HGSLNHLLRTNTFRP
Template Known Secondary structure  SSS.B
SS
B


GGGT



S
SS
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   489490... ......500.........510.........520...... ...530.........540.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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