|   |
2 | . | . | . | . | . | . | |
. | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
| . |
|
|
|
|  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
V | Q | R | I | T | I | A | . |
P | Q | G | P | E | F | S | R | F | V | M | G | Y | W | R | L | M | D | W | N | M | S | A | R | Q | L | V | S | F | I | E | E | H | L | D | L | G | V | T | T | V | D | H | A | D | I | Y | G | G | Y | Q | C | E | A | A | F | G | E | A | L | K | L | A | . |
. |
. |
. |
P | H | L | R | E |
Query Conservation |   |
|   |   |   |   |
|
| . |   |
|
|   |   |
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |   |
|
|
|   |   |
|
|   |
|   |
|
|   |   |
|
|   |
|
|   |   |   | . | . | . | . |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |
|   |
|
|   |   |
|
|   |
|
|
|
|
|   |   |   |
|   | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|
|   |
|
|
|
|   |   |
|
| . | . | . |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
S | K | Y | Q | C | V | K | L | N | D | G | H | F | M | P | V | L | G | F | G | T | Y | A | P | A | E | . |
. |
V | P | K | S | K | A | L | E | A | V | K | L | A | I | E | A | G | F | H | H | I | D | S | A | H | V | Y | N | . |
. |
. |
N | E | E | Q | V | G | L | A | I | R | S | K | I | A | D | G | S | V | K | R | E |
Template Known Secondary structure |   |
T |
|
|
|  |  |  |
| T | T | S |
|  |  |  | S |  |  |  |  |
|
|
|
| T | T | . | . | S |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
|
| G | G | G | S | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| G | G |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |
|  |  |  |
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
|
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
  |
  |   |
77 | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
R | M | E | I | V | S | K | C | G | I | A | T | T | A | R | E | E | N | V | I | G | H | Y | I | T | D | R | D | H | I | I | K | S | A | E | Q | S | L | I | N | L | A | T | D | H | L | D | L | L | L | I | H | R | P | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | L | M | D | A | D |
Query Conservation |   |
  |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | I | F | Y | T | S | K | L | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | N | S | H | R | P | E | L | V | R | P | A | L | E | R | S | L | K | N | L | Q | L | D | Y | V | D | L | Y | L | I | H | F | P | V | S | V | K | P | G | E | E | V | I | P | K | D | E | N | G | K | I | L | F | D | T | V | D | L | C |
Template Known Secondary structure |   |
G |
|  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | G | G | G |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
|  |  |  |  |  |  |
|
| S | S |
| B |
|
| S | S |
| S | S |
| B |
| T | T | S |
| B |
| B |
|
|
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
78 | . | 80 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . |
  |
  |   |
138 | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | |
|
. | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | V | A | D | A | F | K | H | L | H | Q | S | G | K | V | R | H | F | G | V | S | N | F | T | P | A | Q | F | A | L | L | Q | S | R | L | P | . |
. |
F | T | L | A | T | N | Q | V | E | I | S | P | V | H | Q | P | L | L | L | D | G | T | L | D | Q | L | Q | Q | L | R | V | R | P | M | A | W | S | C | L | G | G | G |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |
|   |   |   |
|   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|   |   |
|
Template Sequence |   |
A | T | W | E | A | M | E | K | C | K | D | A | G | L | A | K | S | I | G | V | S | N | F | N | H | R | L | L | E | M | I | L | N | K | P | G | L | K | Y | K | P | V | C | N | Q | V | E | C | H | P | Y | F | N | Q | . |
. |
. |
R | K | L | L | D | F | C | K | S | K | D | I | V | L | V | A | Y | S | A | L | G | S | H |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  | T |
| T | T |
|
|
|
|
| S |  |  |  |  |  |
| B | T | T | B |
|
| . | . | . |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  | S | T | T | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . |
  |
  |   |
216 | . | . | . | 220 | |
|
|
|
. | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . |
Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | L | F | N | D | . |
. |
. |
. |
D | Y | F | Q | P | L | R | D | E | L | A | V | V | A | E | E | L | N | A | G | S | I | E | Q | V | V | Y | A | W | V | L | R | L | P | S | Q | P | L | P | I | I | G | S | G | K | I | E | R | V | R | A | A | V | E | A | E | T | L | K | M | T | R | Q | Q | W | F | R | I | R | K | A |
Query Conservation |   |
  |
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
| . |   |
|   |
|
|
|
|
|
|
|   |
|   |   |   |   |
| . | . |
|
|   |
|   |
|   |   |
|   |
|   |
|
|
|   |
|   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |
|
Template Sequence |   |
R | E | E | P | W | V | D | P | N | S | P | V | L | L | E | D | P | V | L | C | A | L | A | K | K | H | K | . |
R | T | P | A | L | I | A | L | R | Y | Q | L | Q | R | G | V | V | . |
. |
V | L | A | K | S | Y | N | E | Q | R | I | R | Q | N | V | Q | V | F | E | F | Q | L | T | S | E | E | M | K | A | I | D | G | L |
Template Known Secondary structure |   |
|
| T | T | T | S |
| T | T | S |
|
| G | G | G |
|  |  |  |  |  |  |  |  |  |  | T | . |
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|  | . | . |  |  |  |  |
|
| S |  |  |  |  |  |  |  | G | G | G | G | G |
|
|
|
|  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
223 | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
  |
  |   |
292 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
Query Sequence |   |
A | L | G | Y | D | V |
Query Conservation |   |
  |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
Template Sequence |   |
N | R | N | V | R | Y |
Template Known Secondary structure |   |
|
|
|
|
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
  |   |
300 | . | . | . | . | . |
  |