|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | |
. | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | R | T | V | K | V | F | E | E | A | W | P | L | H | T | P | F | V | I | A | R | G | S | R | S | E | A | R | V | V | V | V | E | L | E | E | . |
E | G | I | K | G | T | G | E | C | T | P | Y | P | R | Y | . |
G | E | S | D | A | S | V | M | A | Q | I | M | S | V | V | P | Q | L | E | K | G | L | T | R | E | E | L |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   | . |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |
Template Sequence |   |
I | I | D | I | K | T | S | I | I | K | I | P | L | K | R | T | F | I | T | A | V | R | S | T | N | H | I | D | S | L | A | V | E | L | T | L | D | N | G | V | K | G | Y | G | V | A | P | A | T | T | A | I | T | G | D | T | L | Q | G | X | Q | Y | I | I | R | E | I | F | A | P | V | I | L | G | S | D | L | S | D | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  | T | T |
| B | G | G | G |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
79 | 80 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 |
Predicted Secondary structure |   |
 |  |  |
|
| . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | K | I | L | P | . |
. |
. |
. |
. |
. |
. |
. |
A | G | A | A | R | N | A | L | D | C | A | L | W | D | L | A | A | R | R | Q | Q | Q | S | L | A | D | L | I | G | I | T | L | P | E | T | V | I | T | A | Q | T | V | V | I | G | T | P | D | Q | M | A | N | S | A | S | T | L | W | Q | A | G | A | K | L | L | K | V |
Query Conservation |   |
  |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|   |   |
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
Template Sequence |   |
K | Q | T | L | E | L | A | F | K | K | V | X | F | N | S | A | A | K | X | A | I | D | L | A | Y | H | D | L | L | A | K | E | Q | D | I | S | V | A | K | L | L | G | A | K | A | N | S | . |
I | V | T | D | V | S | I | S | C | G | N | V | A | E | T | I | Q | N | I | Q | N | G | V | E | A | N | F | T | A | I | K | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | B |  |  |  |  |  | T |
|
|
|
|  | . |  |  | B |
|  |  |  |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | |
. | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
151 | . | . | . | |
|
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | |
|
. | . | 220 | . | . | . |
Predicted Secondary structure |   |
 |
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
Query Sequence |   |
K | L | D | N | . |
. |
H | L | I | S | E | R | M | V | A | I | R | T | A | V | P | . |
D | A | T | L | I | V | D | A | N | E | S | W | R | A | E | G | L | A | A | R | C | Q | L | L | A | D | L | G | . |
. |
V | A | M | L | E | Q | P | L | P | A | Q | D | D | A | A | L | E | N | F | I | . |
. |
H | P | L | P | I | C |
Query Conservation |   |
|
|   |   | . | . |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   | . |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   | . | . |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   | . | . |   |   |
|
|
|
|
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |
|
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
Template Sequence |   |
K | T | G | A | D | F | N | R | D | I | Q | L | L | K | A | L | D | N | E | F | S | K | N | I | K | F | R | F | D | A | N | Q | G | W | N | L | A | Q | T | K | Q | F | I | E | E | I | N | K | Y | S | L | N | V | E | I | I | E | Q | P | V | K | Y | Y | D | I | K | A | X | A | E | I | T | K | F | S | N | I | P | V | V |
Template Known Secondary structure |   |
 |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | S |  |  |  |  |  |
| T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|  |  |  |  |  |  |
|
| S |
| T | T |
|  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
|
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
. | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | D | E | S | C | H | T | R | S | N | L | K | A | L | K | . |
. |
G | R | Y | E | M | V | N | I | K | L | D | K | T | G | G | L | T | E | A | L | A | L | A | T | E | A | R | A | Q | G | F | S | L | M | L | G | C | M | L | C | T | S | R | A | I | S | A | A | L | P | L | V | . |
. |
P | Q | V | S | F | A | D | L | D |
Query Conservation |   |
  |
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |   |   |
|   | . | . |   |   |   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | D | E | S | V | F | D | A | K | D | A | E | R | V | I | D | E | Q | A | C | N | X | I | N | I | K | L | A | K | T | G | G | I | L | E | A | Q | K | I | K | K | L | A | D | S | A | G | I | S | C | X | V | G | C | X | X | E | S | P | A | G | I | L | A | T | A | S | F | A | L | A | E | D | I | T | V | A | D | L | D |
Template Known Secondary structure |   |
 | S | T | T |
| S | S |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |
|  |  |  |  | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |
| G |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . |
  |
  |   |
300 | . | . | . | . | . | . | . | . | . | |
310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | P | T | W | L | A | V | D | V | E | . |
P | A | L | Q | F | T | T | G | E | L | H | L |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
P | L | D | W | V | A | K | D | L | Y | S | D | Y | I | T | F | N | E | P | N | I | I | L |
Template Known Secondary structure |   |
G | G | G | G | S |
| G | G | G | T | T | T | T |  |  |  |  | T | T |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
324 | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
  |