|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 30 | . | . | . | . | . | . | |
. | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | R | T | V | K | V | F | E | E | A | W | P | L | H | T | P | F | V | I | A | R | G | S | R | S | E | . |
. |
. |
. |
. |
. |
A | R | V | V | V | V | E | L | E | E | . |
E | G | I | K | G | T | G | E | C | T | P | Y | P | R | Y | G | E | S | D | A | S | V | M | A | Q | I | M | S | V | V | P | Q | L | E | K | G | L |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
|   |   |   |
|
|   |
|   |   | . |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |
|
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|   |
Template Sequence |   |
V | K | K | I | E | S | F | T | L | T | L | P | R | P | N | G | R | G | Y | L | V | R | K | A | N | R | T | V | Y | P | T | F | D | R | S | V | L | V | R | I | E | T | E | N | G | A | V | G | W | G | E | T | Y | G | L | V | . |
. |
. |
. |
A | P | R | A | T | X | E | I | I | D | D | L | L | A | D | F | T | I | G | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | S |  |  |  |  | T | T | T | T |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |
| S | S | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  | T | T | G | G | G | T | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | |
|
|
|
. | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
74 | . | . | . | . | . | 80 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
. | . | 130 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | E | E | L | Q | K | I | L | P | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | A | A | R | N | A | L | D | C | A | L | W | D | L | A | A | R | R | Q | Q | Q | S | L | A | D | L | I | G | I | T | L | P | E | T | V | I | T | A | Q | T | V | V | I | . |
G | T | P | D | Q | M | A | N | S | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|
|
|   |
|
|   |
|
|   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|   |   |
|   |   |   |   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | P | F | D | A | A | A | I | H | D | D | L | Y | D | L | X | R | V | R | G | Y | T | G | G | F | Y | V | D | A | L | A | A | I | D | I | A | L | W | D | L | A | G | K | L | A | G | L | P | V | C | K | L | L | G | G | Q | R | R | D | R | I | A | A | Y | I | S | G | L | P | E | D | T | R | A | K | R | A | E | L | A |
Template Known Secondary structure |   |
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T | G | G | G | T |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | B | G | G | G | G | T | T |
|
|
|
| S |  |  |  |  |  |  |  |
|
|
|
| S | S |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
94 | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
  |
  |   |
138 | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | T | L | W | Q | A | G | A | K | L | L | K | V | K | L | D | N | H | L | I | S | E | R | M | V | A | I | R | T | A | V | P | . |
D | A | T | L | I | V | D | A | N | E | S | W | R | A | E | G | L | A | A | R | C | Q | L | L | A | D | L | G | V | A | M | L | E | Q | P | L | P | A | Q | D | D | A | A | L | E | N | F |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   | . |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |   | . | . | . |   |
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|
Template Sequence |   |
A | A | W | Q | A | K | G | F | S | S | F | K | F | A | S | P | V | A | K | E | X | E | . |
. |
. |
I | L | R | E | R | L | G | P | A | V | R | I | A | C | D | X | H | W | A | H | T | A | S | E | A | V | A | L | I | K | A | X | E | P | H | G | L | W | F | A | E | A | P | V | R | T | E | D | I | D | G | L | A | R | V |
Template Known Secondary structure |   |
 |  |  |  | T | T | T |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  | . | . | . |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |
|
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|  |  |  |  |  |
|
| S |
| T | T |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
|
. | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
  |
  |   |
217 | |
|
. | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
|
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
Predicted Secondary structure |   |
 | . | . |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | . |
. |
H | P | L | P | I | C | A | D | E | S | C | H | T | R | S | N | L | K | A | L | K | . |
. |
G | R | Y | E | M | V | N | I | K | L | D | K | T | G | G | L | T | E | A | L | A | L | A | T | E | A | R | A | Q | G | F | S | L | M | L | G | C | M | L | C | T | S | R | A | I | S | A | A | L | P | L | V | P | Q |
Query Conservation |   |
  | . | . |   |   |
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|   |   |   |   |   |   | . |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |
|
|
|   |
Template Sequence |   |
A | A | S | V | S | T | A | I | A | V | G | E | E | W | R | T | V | H | D | X | V | P | R | V | A | R | R | A | L | A | I | V | Q | P | E | X | G | H | . |
K | G | I | T | Q | F | X | R | I | G | A | Y | A | H | V | H | H | I | K | V | I | P | H | A | T | I | G | A | G | I | F | L | A | A | S | L | Q | A | S | A | A |
Template Known Secondary structure |   |
 | T | T |
| S | S |  |  |  |  |
| T | T |
|
| S | G | G | G | T |  |  |  |  |  | T | T |
|
| S |  |  |
|
|
|  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|
|
|
| S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
256 | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | |
. | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
  |
  |   |
293 | . | . | . | . | . | |
|
|
|
|
. | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | S | F | A | D | L | . |
. |
. |
. |
. |
D | G | P | T | W | L | A | V | D | V | E | P | A | L | Q | F | T | T | G | E | L | H | L |
Query Conservation |   |
  |   |   |   |
|
| . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
L | A | N | V | D | C | H | E | F | Q | H | S | I | F | E | P | N | R | R | L | L | V | G | D | X | D | C | L | N | G | E | Y | V | V |
Template Known Secondary structure |   |
| T | T | B |
|
|  |  |  |
|  |  |  |  | T | G | G | G | G | G |  |  |  | S |
|  |  |  | T | T |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . |
  |