|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | |
. | . | . | 40 | . | . | . | . | . | . | |
|
. | . | . | 50 | . | |
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  | . | . |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | R | T | V | K | V | F | E | E | A | W | P | L | H | T | P | F | V | I | A | R | G | S | R | S | E | A | R | V | V | V | V | E | L | E | E | . |
E | G | I | K | G | T | G | E | C | T | . |
. |
P | Y | P | R | Y | . |
G | E | S | D | A | S | V | M | A | Q | I | M | S | V | V | P | Q | L | E | K | G | L | T | R | E |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   | . |   |
|   |   |
|   |
|
|   |   | . | . |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |
Template Sequence |   |
F | Q | K | A | R | L | I | H | A | E | L | P | L | L | A | P | F | K | T | S | Y | G | E | L | K | S | K | D | F | Y | I | I | E | L | I | N | E | E | G | I | H | G | Y | G | E | L | E | A | F | P | L | P | D | Y | T | E | E | T | L | S | S | A | I | L | I | I | K | E | Q | L | L | P | L | L | A | Q | R | K | I | R |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |
|
|
| S | S | T | T | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
|  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2003 | . | . | . | . | . | . | 2010 | . | . | . | . | . | . | . | . | . | 2020 | . | . | . | . | . | . | . | . | . | 2030 | . | . | . | . | . | . | . | . | . | 2040 | . | . | . | . | . | . | . | . | . | 2050 | . | . | . | . | . | . | . | . | . | 2060 | . | . | . | . | . | . | . | . | . | 2070 | . | . | . | . | . | . | . | . | . | 2080 | . | . |
  |
  |   |
77 | . | . | 80 | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | Q | K | I | L | P | . |
. |
. |
. |
. |
. |
. |
A | G | A | A | R | N | A | L | D | C | A | L | W | D | L | A | A | R | R | Q | Q | Q | S | L | A | D | L | I | G | I | T | L | P | E | T | V | I | T | A | Q | T | V | V | I | G | T | P | D | Q | M | A | N | S | A | S | T | L | W | Q | A | G | A | K | L | L | K |
Query Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|
|   |   |
|   |   |
|   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
Template Sequence |   |
K | P | E | E | I | Q | E | L | F | S | W | I | Q | G | N | E | M | A | K | A | A | V | E | L | A | V | W | D | A | F | A | K | M | E | K | R | S | L | A | K | M | I | G | A | T | K | E | S | I | K | V | G | V | S | I | G | L | Q | Q | N | V | E | T | L | L | Q | L | V | N | Q | Y | V | D | Q | G | Y | E | R | V | K |
Template Known Secondary structure |   |
S | T | T |  |  |  |  |  | T | T | T | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | B |  |  |  |  | T | T |
|
|
| S |  |  |  | B |
|  |  |  |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2083 | . | . | . | . | . | . | 2090 | . | . | . | . | . | . | . | . | . | 2100 | . | . | . | . | . | . | . | . | . | 2110 | . | . | . | . | . | . | . | . | . | 2120 | . | . | . | . | . | . | . | . | . | 2130 | . | . | . | . | . | . | . | . | . | 2140 | . | . | . | . | . | . | . | . | . | 2150 | . | . | . | . | . | . | . | . | . | 2160 | . | . |
  |
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
V | K | L | D | N | H | L | I | S | E | R | M | V | A | I | R | T | A | V | P | D | A | T | L | I | V | D | A | N | E | S | W | R | A | E | G | L | A | A | R | C | Q | L | L | A | D | L | G | V | A | M | L | E | Q | P | L | P | A | Q | D | D | A | A | L | E | N | F | I | H | P | . |
. |
L | P | I | C | A | D | E | S |
Query Conservation |   |
|
|
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . |
|
|
|
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |   |   |
|   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   | . |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|   |
Template Sequence |   |
L | K | I | A | P | N | K | D | I | Q | F | V | E | A | V | R | K | S | F | P | K | L | S | L | M | A | D | A | N | S | A | Y | N | R | E | D | F | L | . |
L | L | K | E | L | D | Q | Y | D | L | E | M | I | E | Q | P | F | G | T | K | D | F | V | D | H | A | W | L | Q | K | Q | L | K | T | R | I | C | L | D | E | N |
Template Known Secondary structure |   |
 |  |
| B | T | T | B | S |  |  |  |  |  |  |  |  | T | T |
| T | T | S |  |  |  |  |  |
| T | T |
|
|
| G | G | G |  |  | . |  |  |  |  |  |  | T | T | T |
| S |  |  |  |
|
| S |
| S | S |
| S |  |  |  |  |  |  |  | T | T |
| S | S |  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2163 | . | . | . | . | . | . | 2170 | . | . | . | . | . | . | . | . | . | 2180 | . | . | . | . | . | . | . | . | . | 2190 | . | . | . | . | . | . | . | . | . | 2200 | |
. | . | . | . | . | . | . | . | . | 2210 | . | . | . | . | . | . | . | . | . | 2220 | . | . | . | . | . | . | . | . | . | 2230 | . | . | . | . | . | . | . | . | . | 2240 | . |
  |
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | |
|
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | |
|
|
. | . | . | . | 300 | . | |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|  |  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
| . |
Query Sequence |   |
C | H | T | R | S | N | L | K | A | L | K | . |
. |
G | R | Y | E | M | V | N | I | K | L | D | K | T | G | G | L | T | E | A | L | A | L | A | T | E | A | R | A | Q | G | F | S | L | M | L | G | C | M | L | C | T | S | R | A | I | S | A | A | L | P | L | V | P | Q | V | S | F | . |
. |
. |
A | D | L | D | G | P | . |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   | . | . | . |   |
|
|   |   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | R | S | V | K | D | V | E | Q | A | H | S | I | G | S | C | R | A | I | N | L | K | L | A | R | V | G | G | M | S | S | A | L | K | I | A | E | Y | C | A | L | N | E | I | L | V | W | C | G | G | M | L | E | A | G | V | G | R | A | H | N | I | A | L | A | A | R | N | E | F | V | F | P | G | D | I | S | A | S | N |
Template Known Secondary structure |   |
|
| S |  |  |  |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  |
| T | G | G | G | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | S | S | S |
|
| S |
| B | S |
|
|
| G | G |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2242 | . | . | . | . | . | . | . | 2250 | . | . | . | . | . | . | . | . | . | 2260 | . | . | . | . | . | . | . | . | . | 2270 | . | . | . | . | . | . | . | . | . | 2280 | . | . | . | . | . | . | . | . | . | 2290 | . | . | . | . | . | . | . | . | . | 2300 | . | . | . | . | . | . | . | . | . | 2310 | . | . | . | . | . | . | . | . | . | 2320 | . |
  |
  |   |
302 | . | . | . | . | . | . | . | |
310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
| . |
|
|
|  |  |  |
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | W | L | A | V | D | V | E | . |
P | A | L | Q | F | T | T | G | E | L | H | L |
Query Conservation |   |
  |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
Template Sequence |   |
R | F | F | A | E | D | I | V | T | P | A | F | E | L | N | Q | G | R | L | K | V |
Template Known Secondary structure |   |
G | T | B | S | S |
| S | B | S | S |
|
|
|
|
| S | S |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2322 | . | . | . | . | . | . | . | 2330 | . | . | . | . | . | . | . | . | . | 2340 | . | . |
  |