Job Description P16694 Confidence 99.52% Date Thu Jan 5 11:35:44 GMT 2012 Rank 19 Aligned Residues 524 % Identity 13% Template c1f5nA_ PDB info PDB header:signaling protein Chain: A: PDB Molecule:interferon-induced guanylate-binding protein 1; PDBTitle: human guanylate binding protein-1 in complex with the gtp2 analogue, gmppnp. Resolution 1.70 Å

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		56	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.		.	.	.	.	.	.	100			.	.	.	.		.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.
Predicted Secondary structure																																								.								.	.					.
Query SS confidence																																								.								.	.					.
Query Sequence		A	M	L	N	N	E	L	R	K	I	S	R	L	E	M	V	L	A	I	V	G	T	M	K	A	G	K	S	T	T	I	N	A	I	V	G	T	E	.	V	L	P	N	R	N	R	.	.	P	M	T	A	.	L	P	T	L	I	R	H	T	P	G	Q	K	E	P	V	L	H	F	S	H	V	A	P	I	D	C	L
Query Conservation																																								.								.	.					.
Alig confidence																																								.								.	.					.																.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																																						.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		P	E	A	L	K	I	L	S	A	I	T	Q	P	M	V	V	V	A	I	V	G	L	Y	R	T	G	K	S	Y	L	M	N	K	L	A	G	K	K	K	G	F	S	L	G	S	T	V	Q	S	H	T	K	G	I	W	M	W	C	V	P	H	P	K	K	P	G	H	I	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure										T			S	B									B	T	T	S	S									T	T		S	S		S					S	S	S					S									S	S	S	T	T			.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																																						.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		25	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.
		132	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	Q	Q	L	Q	Q	R	L	R	D	C	D	I	K	H	L	T	D	V	L	E	I	D	K	D	M	R	A	L	M	Q	R	I	E	N	G	V	A	F	E	K	Y	Y	L	G	A	Q	P	I	F	H	C	L	K	S	L	N	D	L	V	R	L	A	K	A	L	D	V	D	F	P	F	S	A	Y	A	A	I	E	H
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		212	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.				.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.
Predicted Secondary structure																																	.	.	.																																														.
Query SS confidence																																	.	.	.																																														.
Query Sequence		I	P	V	I	E	V	E	F	V	H	L	A	G	L	E	S	Y	P	G	Q	L	T	L	L	D	T	P	G	P	N	E	.	.	.	A	G	Q	P	H	L	Q	K	M	L	N	Q	Q	L	A	R	A	S	A	V	L	A	V	L	D	Y	T	Q	L	K	S	I	S	D	E	E	V	R	E	A	I	L	A	V	G	.
Query Conservation																																	.	.	.																																														.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.												.	.	.																							.	.																						.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																					.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	V	L	L	D	T	E	G	L	G	D	V	E	K	G	D	N	Q	N	D	S	W	I	F	A	L	A	V	L	L	S	S	T	F	V	Y	.	.	N	S	I	G	T	I	N	Q	Q	A	M	D	Q	L	Y	Y	V	T	E	L	T	H
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.									B			G	G	G				T	T													S					.	.				S		S	S						T	T					T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																					.	.
Template SS confidence
																						93	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.			.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150
																		288	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Q	S	V	P	L	Y	V	L	V	N	K	F	D	Q	Q	D	R	N	S	D	D	A	D	Q	V	R	A	L	I	S	G	T	L	M	K	G	C	I	T	P	Q	Q	I	F	P	V	S	S	M	W	G	Y	L	A	N	R	A	R	Y	E	L	A	N	N
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		R	I	R	S	K	S	S	V	E	D	S	A	D	F	V	S	F	F	P	D	F	V	W	T	L	R	D	F	S	L	D	L	E	A	D	G	Q	P	L	T	P	D	E	Y	L	T	Y	S	L	K	L	K	K	G	T	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Q	K	D	E	T
Template Known Secondary structure				B	S						G	G	G	G														T								S	S	S												T							S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		151	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.																				.	.	.	210	.
		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.				.	.	.	.	.	420	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																	.	.	.
Query SS confidence																																																																	.	.	.
Query Sequence		G	K	L	P	P	P	E	Q	Q	R	W	V	E	D	F	A	H	A	A	L	G	R	R	W	R	H	A	D	L	A	D	L	E	H	I	R	H	A	A	D	Q	L	W	E	D	S	L	F	A	Q	P	I	Q	A	L	L	H	A	A	Y	A	N	A	.	.	.	S	L	Y	A	L	R	S	A	A	H	K	L	L	N
Query Conservation																																																																	.	.	.
Alig confidence																																																																	.	.	.
Template Conservation
Template Sequence		F	N	L	P	R	L	C	I	R	K	F	F	P	K	K	K	C	F	V	F	D	R	P	V	H	R	R	K	L	A	Q	L	E	K	L	Q	D	E	E	L	D	P	E	F	V	Q	Q	V	A	D	F	C	S	Y	I	F	S	N	S	K	T	K	T	L	S	G	G	I	Q	V	N	G	P	R	L	E	S	L	V	L
Template Known Secondary structure														S											S		G	G	G	G	G	G	G	G	G	S		G	G	G	S																									T	T	T				B
Template Predicted Secondary structure
Template SS confidence
		219	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
		429	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	A	Q	Q	A	R	E	Y	L	D	F	R	A	H	G	L	N	V	A	C	E	Q	L	R	Q	N	I	H	Q	I	E	E	S	L	Q	L	L	Q	L	N	Q	A	Q	V	S	G	E	I	K	H	E	I	E	L	A	L	T	S	A	N	H	F	L	R	Q	Q	Q	D	A	L	K	V	Q	L	A	A	L	F	Q	D
Query Conservation
Alig confidence																																																																			.	.	.	.	.
Template Conservation																																																																			.	.	.	.	.
Template Sequence		T	Y	V	N	A	I	S	S	G	D	L	P	C	M	E	N	A	V	L	A	L	A	Q	I	E	N	S	A	A	V	Q	K	A	I	A	H	Y	E	Q	Q	M	G	Q	K	V	Q	L	P	T	E	S	L	Q	E	L	L	D	L	H	R	D	S	E	R	E	.	.	.	.	.	A	I	E	V	F	I	R	S	S	F
Template Known Secondary structure										T	S			B																																		S	S		S	S															.	.	.	.	.
Template Predicted Secondary structure																																																																			.	.	.	.	.
Template SS confidence
		299	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.						.	.	.	.	.	.	370	.	.	.
		509	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	S	E	P	L	S	E	I	R	T	R	C	E	T	L	L	Q	T	A	Q	N	T	I	S	R	D	F	T	L	R	F	A	E	L	E	S	T	L	C	R	V	L	T	D	V	I	R	P	I	E	Q	Q	V	K	M	E	L	S	E	S	G	F	R	P	G	F	H	F	P	V	F	H	G	V	V	P	H	F	N	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	D	V	D	H	L	F	Q	K	E	L	A	A	Q	L	E	K	K	R	D	D	F	C	K	Q	N	Q	E	A	S	S	D	R	C	S	G	L	L	Q	V	I	F	S	P	L	E	E	E	V	K	A	G	I	Y	S	K	P	G	G	Y	R	L	F	V	Q	K	L	Q	D	L	K	K	K	Y	Y	E	E	P	R	K
Template Known Secondary structure				G	G	G																																														T	T	T	T	S	S	T	T																			S	S
Template Predicted Secondary structure
Template SS confidence
		374	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.
		589	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Q	L	F	S	E	V	I	S	R	Q	E	A	T	D	E	Q	S	T	R	L	G	V	V	R	E	T	F	S	R	W	L	N	Q	P	D	W	G	R	G	N	E	K	S	P	T	E	T	V	D	Y	S	V	L	Q	R	A	L	S	A	E	V	D	L	Y	C	Q	Q	M	A	K	V	L	A	E	Q	V	D	E	S
Query Conservation
Alig confidence															.	.	.	.	.	.
Template Conservation															.	.	.	.	.	.
Template Sequence		G	I	Q	A	E	E	I	L	Q	T	Y	L	K	.	.	.	.	.	.	S	K	E	S	M	T	D	A	I	L	Q	T	D	Q	T	L	T	E	K	E	K	E	I	E	V	E	R	V	K	A	E	S	A	Q	A	S	A	K	M	L	H	E	M	Q	R	K	N	E	Q	M	M	E	Q	K	E	R	S	Y	Q	E	H
Template Known Secondary structure			T	T											.	.	.	.	.	.		T												S	S	S
Template Predicted Secondary structure															.	.	.	.	.	.
Template SS confidence
		454	.	.	.	.	.	460	.	.	.	.	.	.							.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.
		669	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	T	A	G	M	N	T	F	F	A	E	F	A	S	C	L	T	E	L	Q	T	R	L	R	E	S	L	A	L	R	Q	Q	N	E	S	V	V	R	L	M	Q	Q	Q	L	Q	Q	T	V	M	T	H	G	W	I	Y	T	D
Query Conservation
Alig confidence																														.	.
Template Conservation																														.	.
Template Sequence		L	K	Q	L	T	E	K	M	E	N	D	R	V	Q	L	L	K	E	Q	E	R	T	L	A	L	K	L	Q	.	.	E	Q	E	Q	L	L	K	E	G	F	Q	K	E	S	R	I	M	K	N	E	I	Q	D	L	Q	T	K
Template Known Secondary structure																														.	.									T
Template Predicted Secondary structure																														.	.
Template SS confidence
		528	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.			.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.