|   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | |
. | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | Y | R | H | Y | M | Q | K | E | I | Y | E | Q | P | N | A | I | K | N | T | L | T | G | R | I | S | H | G | Q | V | D | L | S | . |
E | L | G | P | N | A | D | E | L | L | S | K | V | E | H | I | Q | I | L | A | C | G | T | S | Y | N | S | G | M | V | S | R | Y | W | F | E | S | L | A | G | I | P | C | D | V | E |
Query Conservation |   |
  |
|   |
|   |
|   |
|
|
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | Y | K | H | F | M | Q | K | E | I | F | E | Q | P | D | S | A | F | N | T | M | R | G | R | I | D | F | E | N | C | V | V | T | L | G | G | L | K | S | W | L | S | T | I | R | R | C | R | R | I | I | M | I | A | C | G | T | S | Y | H | S | C | L | A | T | R | S | I | F | E | E | L | T | E | I | P | V | S | V | E |
Template Known Secondary structure |   |
|
| S | S |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  | T | T | T |  |  | T | T | T | T |  |  |
|
| T | G | G | G | G | T |  |  |  |  |  | T |
| S |
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . |
  |
  |   |
327 | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | A | S | E | F | R | Y | R | K | S | A | V | R | R | N | S | L | M | I | T | L | S | Q | S | G | E | T | A | D | T | L | A | G | L | R | L | S | K | E | L | G | Y | L | G | S | L | A | I | C | N | V | P | G | S | S | L | V | R | E | S | D | L | A | L | M | T | N | A | G | T | E | I | G | V | A | S | T | K | A | F |
Query Conservation |   |
  |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|   |
|   |   |
|
|   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |
|   | . |   |   |
|   |
|
|   |   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|   |
Template Sequence |   |
L | A | S | D | F | L | D | R | R | S | P | V | F | R | D | D | T | C | V | F | V | S | Q | S | G | E | T | A | D | S | I | L | A | L | Q | Y | C | L | E | R | G | A | . |
L | T | V | G | I | V | N | S | V | G | S | S | M | S | R | Q | T | H | C | G | V | H | I | N | A | G | P | E | I | G | V | A | S | T | K | A | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
|
|
|
| T | T |
|  |  |  |  |  |  | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . |  |  |  |  |  |  | S | S | S | S |
|  |  |  |  |  | S | S |  |  |  |  |
|
|
|
|
|
|
| S | S | S |
| S |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
429 | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | |
. | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . |
  |
  |   |
407 | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | T | Q | L | T | V | L | L | M | L | V | A | K | L | S | R | L | K | G | L | D | A | S | I | E | H | D | I | V | H | G | L | Q | A | L | P | S | R | I | E | Q | M | L | S | Q | D | K | R | I | E | A | L | A | E | D | F | S | D | K | H | H | A | L | F | L | G | R | G | D | Q | Y | P | I | A | L | E | G | A | L | K |
Query Conservation |   |
|   |   |
|
|   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |
|   |
|
|
|
Template Sequence |   |
T | S | Q | Y | I | A | L | V | M | F | A | L | S | L | S | N | D | S | I | S | R | K | G | R | H | E | E | I | I | K | G | L | Q | K | I | P | E | Q | I | K | Q | V | L | K | L | E | N | K | I | K | D | L | C | N | S | . |
. |
S | Q | K | S | L | L | L | L | G | R | G | Y | Q | F | A | T | A | L | E | G | A | L | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  | G | G | G | . | . |
|
|
|  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
508 | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | |
|
. | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . |
  |
  |   |
487 | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | |
550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | E | I | S | Y | I | H | A | E | A | Y | A | A | G | E | L | K | H | G | P | L | A | L | I | D | A | D | M | P | V | I | V | V | A | P | N | N | E | L | L | E | K | L | K | S | N | I | E | E | V | R | A | R | G | G | Q | L | Y | V | F | A | D | . |
Q | D | A | G | F | V | S | S | D | N | M | H | I | I | E | M |
Query Conservation |   |
|   |
|   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|
|
|   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|   |
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|
| . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | K | E | I | S | Y | M | H | S | E | G | V | L | A | G | E | L | E | D | L | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
I | I | A | F | A | T | R | D | S | L | F | P | K | V | M | S | A | I | E | Q | V | T | A | R | D | G | R | P | I | V | I | C | N | E | G | D | A | I | I | S | N | D | K | V | H | T | T | L | E | V |
Template Known Secondary structure |   |
 |  |  | T | T |
| S |  |  |  |  |  |  | T | T |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |
|
| T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  | T | T |
|
|
| S |
| T | T | S |
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
589 | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . |
  |
  |   |
566 | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | H | V | E | E | V | I | A | P | I | F | Y | T | V | P | L | Q | L | L | A | Y | H | V | A | L | I | K | G | T | D | V | D |
Query Conservation |   |
|   |   |   |   |   |
|   |
|
|   |   |   |
|
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|   |   |
|
|   |   |   |
|
|
|
|
|
Template Sequence |   |
P | E | T | V | D | C | L | Q | G | L | L | N | V | I | P | L | Q | L | I | S | Y | W | L | A | V | N | R | G | I | D | V | D |
Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
669 | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 |
  |