|   |
251 | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | Y | M | Q | K | E | I | Y | E | Q | P | N | A | I | K | N | T | L | T | G | R | I | S | H | G | Q | V | D | L | S | E | L | G | P | N | A | D | E | L | L | S | K | V | E | H | I | Q | I | L | A | C | G | T | S | Y | N | S | G | M | V | S | R | Y | W | F | E | S | L | A | G | I | P | C | D | V | E | I | A | S | E |
Query Conservation |   |
|   |
|   |
|
|
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |
|   |   | . | . |   |   |   |   |   |
|   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
G | F | N | Q | D | E | Y | L | T | S | A | R | E | I | I | A | A | R | Q | K | . |
. |
. |
. |
. |
. |
. |
. |
A | E | Q | V | A | D | E | I | Y | Q | . |
. |
A | G | F | S | S | L | F | F | A | S | V | G | G | S | L | A | P | X | X | A | I | N | E | F | A | K | E | L | T | T | L | P | V | Y | V | E | Q | A | A | E |
Template Known Secondary structure |   |
T |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
| S |
|  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
30 | . | . | . | . | . | . | . | . | . | |
|
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
331 | . | . | . | . | |
. | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
| . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | R | Y | R | K | . |
S | A | V | R | R | N | S | L | M | I | T | L | S | Q | S | G | E | T | A | D | T | L | A | G | L | R | L | S | K | E | L | G | Y | L | G | S | L | A | I | C | N | V | P | G | S | S | L | V | R | E | S | D | L | A | L | M | T | N | A | G | T | E | I | G | V | A | S | T | K | A | F | T | T | Q |
Query Conservation |   |
|   |   |   |   | . |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|   |
|   |   |
|
|   |
|
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|   |
|   |
|   |
|   |
|   |   |   |
|   |   |   |
| . |   |   |   |
|   |
|
|   |   |   |   |
|   |
|   |   |   |
|
|   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
L | I | H | K | G | N | K | R | L | N | K | D | S | V | V | I | T | L | S | K | S | G | D | T | K | E | S | V | A | I | A | E | W | C | K | A | Q | G | . |
I | R | V | V | A | I | T | K | N | A | D | S | P | L | A | Q | A | A | T | W | H | I | P | X | R | H | K | N | G | V | E | Y | E | Y | X | L | L | Y | W | L | F |
Template Known Secondary structure |   |
 |  |  |  |
|
| T | T |
|
| T | T |
|  |  |  |  |  |
| S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | . |
|  |  |  |  |  |  | S |
| T | T | S |  |  |  |  | T |
| S |  |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | |
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | |
. | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | |
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  | . |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Query Sequence |   |
L | T | V | L | L | M | L | V | A | K | L | S | R | L | K | G | L | D | A | S | I | E | H | D | I | V | H | G | L | Q | A | L | P | S | R | I | E | Q | M | L | S | Q | . |
D | K | R | I | E | A | L | A | E | D | F | S | D | K | H | H | A | L | F | L | G | R | G | D | Q | Y | P | I | A | . |
L | E | G | A | L | K | L |
Query Conservation |   |
|
|   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
| . |   |
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |
|
|
|
|
Template Sequence |   |
F | R | V | L | S | R | N | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
E | F | A | S | Y | D | R | F | A | S | Q | L | E | I | L | P | A | N | L | L | K | A | K | Q | K | F | D | P | Q | A | D | A | I | A | S | R | Y | H | N | S | D | Y | X | X | W | V | G | G | A | E | X | W | G | E | V | Y | L | F | S | X | C | I | L |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | . | . | . | . | . | . | . | . | . | S |
| T | T |  |  |  |  |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |  | T |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
  |
  |   |
488 | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | E | I | S | Y | I | H | A | E | A | Y | A | A | G | E | L | K | H | G | P | L | A | L | I | D | A | D | M | P | V | I | V | V | A | P | N | N | E | L | L | E | K | L | K | S | N | I | E | E | V | R | A | R | G | G | Q | L | Y | V | F | A | D | Q | D | A | G | F | V | S | S | D | N | M | H | I | I | E | M | P | H |
Query Conservation |   |
  |
|   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|
|
|   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
Template Conservation |   |
  |
|   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . |   |   |
Template Sequence |   |
E | E | X | Q | W | K | R | T | R | P | V | S | S | A | E | F | F | H | G | A | L | E | L | L | E | K | D | V | P | L | I | L | V | K | G | E | G | K | C | R | A | L | D | E | R | V | E | R | F | A | S | K | I | T | D | N | L | V | V | I | D | P | K | A | Y | A | L | D | G | I | D | . |
. |
. |
. |
. |
. |
. |
D | E |
Template Known Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | T | T | T | G | G | G | G |
|
| T | T |
|
|  |  |  |  |
|
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |
| G | G | G | S |
|
| T | T | S |
| . | . | . | . | . | . | . | G | G |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | |
|
|
|
|
|
|
. | . |
  |
  |   |
568 | . | 570 | . | . | . | . | |
. | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | E | E | V | I | A | P | . |
I | F | Y | T | V | P | L | Q | L | L | A | Y | H | V | A | L | I | K | G | T | D | V | D | Q | P | R | N | L | A | K | S |
Query Conservation |   |
  |   |   |   |
|   |
| . |
|   |   |   |
|
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |
|
|
|   |
|
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |
|
|
|   |   |
|   |
Template Sequence |   |
F | R | W | I | X | A | P | C | V | V | S | T | L | L | V | D | R | L | A | A | H | F | E | K | Y | T | G | H | S | L | D | I | R | R | Y | Y | R | Q | F |
Template Known Secondary structure |   |
G |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T |
|
| S | S | T | T | T | S |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
  |