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Job DescriptionP32138
Confidence100.00%DateThu Jan 5 11:49:24 GMT 2012
Rank3Aligned Residues579
% Identity20%Templatec3topA_
PDB info PDB header:hydrolase/hydrolase inhibitorChain: A: PDB Molecule:maltase-glucoamylase, intestinal; PDBTitle: crystral structure of the c-terminal subunit of human maltase-2 glucoamylase in complex with acarbose
Resolution2.88 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  NFSIKDKLQEKIALTDAIV. . . . SQSPDGWLIHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQ. PEDH
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Template Sequence  QFKIYDPNKNRYEVPVPLNIPSMPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFSDMFIRISTRLPSKY
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   1051........1060.........1070.........1080.........1090.........1100.........1110.........1120.........1130
 
   129130........ .140.........150.........160.........170.........180.........190.. .......200.
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Query Sequence  IYGCGEQFSY. . . FDLRGKPFPLWTSEQGVGRNKQTYVTWQADCKENAGGDYYWTFFPQPTFVSTQK. . . . YYCHVDNSC
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Template Sequence  LYGFGETEHRSYRRDLEWHTWGMFSRDQPPGYKK. . . . . . . . . . . . . . . . . . . NSYGVHPYYMGLEEDGSAHGVLLLNSN
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   1131........1140.........1150.........1160.... .....1170.........1180.........1190.
 
   202.......210.........220.........230.........240.........250.........260. ........270.........280
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Query Sequence  YMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLTALLGRQPELPDWIYDGVTLGI. QGGTEVCQKKLDTMRNAGV
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Template Sequence  AMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQI
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   1192.......1200.........1210.........1220.........1230.........1240.........1250.........1260.........1270.
 
   281....... .290.........300.........310.........320.........330.........340. ........350.....
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Query Sequence  KVNGIWAQ. DWSGIRMTSFGKRVMWNWKWNSENYPQLDSRIKQWNQEGVQFLAYINPYVASD. . . . KDLCEEAAQHGYLA
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Template Sequence  PYDVQYSDIDYMERQL. . . . . . . . . DFTLSP. KFAGFPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFI
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GGGSSTT
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   1272.......1280....... ..1290... ......1300.........1310.........1320.........1330.........1340.
 
   356.. .360......... 370.........380.........390..... ....400......
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Query Sequence  KDA. SGGDYLVEFGE. . . . . . . . . . . . . . . . . . . . . FYGGVVDLTNPEAYAWFKEVIKKNMI. . . . . . . ELGCGGWMADF
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Template Sequence  KYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDM
Template Known Secondary structure  B
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   1342.......1350.........1360.........1370.........1380.........1390.........1400.........1410.........1420.
 
   407. .410....... ..420.........430.........440.....
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Query Sequence  GE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . YLPTDTYLH. . . . NGVSAEIMHNAWPALWAKCNYEALEETG
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Template Sequence  NEPSSFVNGAVSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQEV.
Template Known Secondary structure  TTT

SSSSSSSS



TTTSS
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TTGGGTTTTTS

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   1422.......1430.........1440.........1450.........1460.........1470.........1480.........1490.........1500
 
   446...450.........460.........470.........480.........490.........500.........510.........520.....
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Query Sequence  KLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWC
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Template Sequence  TGQRGVVITRSTFPSSGRWAG. HWLGDNTAAWDQ. . . LKKSIIGMMEFSLFGISYTGADICGFFQ. . . . DAEYEMCVRWM
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   1501........1510.........1520. ........1530... ......1540.........1550.........1560. ........1570..
 
   526...530.........540.........550.........560.........570.........580.........590.........600.....
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Query Sequence  DFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKY
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Template Sequence  QLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDS
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   1573......1580.........1590.........1600.........1610.........1620.........1630.........1640.........1650..
 
   606...610.........620.........630.........640...... .. .650.........660.........670
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Query Sequence  QYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWTGEAFRG. GE. VTVNAPIGKPPVFYRADSEWAA
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Template Sequence  QFLLGPAFLVSPVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPW
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   1653......1660.........1670.........1680.........1690.........1700.........1710.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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