Job Description P69451 Confidence 100.00% Date Thu Jan 5 12:11:41 GMT 2012 Rank 7 Aligned Residues 514 % Identity 24% Template c3eynB_ PDB info PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa Resolution 1.90 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.						.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																												.	.	.	.	.
Query SS confidence																																												.	.	.	.	.
Query Sequence		W	L	N	R	Y	P	A	D	V	P	T	E	I	N	P	D	R	Y	Q	S	L	V	D	M	F	E	Q	S	V	A	R	Y	A	D	Q	P	A	F	V	N	M	G	.	.	.	.	.	E	V	M	T	F	R	K	L	E	E	R	S	R	A	F	A	A	Y	L	Q	Q	G	L	G	L	K	K	G	D	R	V	A	L
Query Conservation																																												.	.	.	.	.
Alig confidence			.	.	.																																							.	.	.	.	.
Template Conservation			.	.	.
Template Sequence		W	.	.	.	G	H	Q	E	V	P	A	K	F	N	F	A	S	D	V	L	D	H	W	A	D	M	E	K	A	G	K	R	P	P	S	P	A	L	W	W	V	N	G	K	G	K	E	L	M	W	N	F	R	E	L	S	E	N	S	Q	Q	A	A	N	V	L	S	G	A	C	G	L	Q	R	G	D	R	V	A	V
Template Known Secondary structure			.	.	.		B					S	B							T										T	T	S	S											S	S	S																							T	T	T				T	T
Template Predicted Secondary structure			.	.	.
Template SS confidence
		35				.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	M	P	N	L	L	Q	Y	P	V	A	L	F	G	I	L	R	A	G	M	I	V	V	N	V	N	P	L	Y	T	P	R	E	L	E	H	Q	L	N	D	S	G	A	S	A	I	V	I	V	S	N	F	A	H	T	L	E	K	V	V	D	K	T	A	V	Q	H	V	I	L	T	R	M	G	D	Q	L	S	T	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	L	P	R	V	P	E	W	W	L	V	I	L	G	C	I	R	A	G	L	I	F	M	P	G	T	I	Q	M	K	S	T	D	I	L	Y	R	L	Q	M	S	K	A	K	A	I	V	A	G	D	E	V	I	Q	E	V	D	T	V	A	S	E	C	P	S	L	R	I	K	L	L	V	S	E	K	S	C	D	G	W
Template Known Secondary structure					S														T	T								T	T														T		S						T	T	T								G	G	G		T	T								S	S	S			T	T
Template Predicted Secondary structure
Template SS confidence
		112	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.
		160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	G	T	V	V	N	F	V	V	K	Y	I	K	R	L	V	P	K	Y	H	L	P	D	A	I	S	F	R	S	A	L	H	N	G	Y	R	M	Q	Y	V	K	P	E	L	V	P	E	D	L	A	F	L	Q	Y	T	G	G	T	T	G	V	A	K	G	A	M	L	T	H	R	N	M	L	A	N	L	E	Q	V	N
Query Conservation
Alig confidence																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	N	F	K	K	L	L	N	E	A	S	T	T	H	H	C	V	E	T	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	Q	E	A	S	A	I	Y	F	T	S	G	L	P	K	M	A	E	H	S	Y	S	S	L	G	L	K	A	K	M	D	A
Template Known Secondary structure											S		S								B	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	T	S																													T
Template Predicted Secondary structure																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		192	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.																													.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	T	Y	G	P	L	L	H	P	G	K	E	L	V	V	T	A	L	P	L	Y	H	I	F	A	L	T	I	N	C	L	L	F	I	E	L	G	G	Q	N	L	L	I	T	N	P	R	D	I	P	G	L	V	K	E	L	A	K	Y	P	F	T	A	I	T	G	V	N	T	L	F	N	A	L	L	N	N	K	E	F
Query Conservation
Alig confidence												.	.																																																																				.
Template Conservation												.	.																																																																				.
Template Sequence		G	W	T	G	L	Q	A	S	D	I	.	.	M	W	T	I	S	D	T	G	W	I	L	N	I	L	C	S	L	M	E	P	W	A	L	G	A	C	T	F	V	H	L	L	P	K	F	D	P	L	V	I	L	K	T	L	S	S	Y	P	I	K	S	M	M	G	A	P	I	V	Y	R	M	L	L	Q	Q	D	L	.
Template Known Secondary structure		T	T	T	S			T	T			.	.							T	T	S							T	T							T									S	S													S																	T	S		T	.
Template Predicted Secondary structure												.	.																																																																				.
Template SS confidence
		247	.	.	250	.	.	.	.	.	.			.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.
		320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	Q	L	D	F	S	S	L	H	L	S	A	G	G	G	M	P	V	Q	Q	V	V	A	E	R	W	V	K	L	T	G	Q	Y	L	L	E	G	Y	G	L	T	E	C	A	P	L	V	S	V	N	P	Y	D	I	D	Y	H	S	G	S	I	G	L	P	V	P	S	T	E	A	K	L	V	D	D	D	D	N	E	V
Query Conservation
Alig confidence																																																							.
Template Conservation																																																							.
Template Sequence		S	S	Y	K	F	P	H	L	Q	N	C	V	T	V	G	E	S	L	L	P	E	T	L	E	N	W	R	A	Q	T	G	L	D	I	R	E	S	Y	G	Q	T	E	T	G	L	T	C	M	V	S	K	T	M	.	K	I	K	P	G	Y	M	G	T	A	A	S	C	Y	D	V	Q	I	I	D	D	K	G	N	V	L
Template Known Secondary structure		T	S	S			T	T								S	S															S										T	T	T								T	T	S	.				T	T							T	T								T	T	S		B
Template Predicted Secondary structure																																																							.
Template SS confidence
		324	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.		.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.
		400	.	.	.	.	.	.	.	.	.	410	.	.						.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.
Predicted Secondary structure															.	.	.	.	.
Query SS confidence															.	.	.	.	.
Query Sequence		P	P	G	Q	P	G	E	L	C	V	K	G	P	.	.	.	.	.	Q	V	M	L	G	Y	W	Q	R	P	D	A	T	D	E	I	I	K	N	G	W	L	H	T	G	D	I	A	V	M	D	E	E	G	F	L	R	I	V	D	R	K	K	D	M	I	L	V	S	G	F	N	V	Y	P	N	E	I	E	D	V	V
Query Conservation															.	.	.	.	.
Alig confidence															.	.	.	.	.
Template Conservation
Template Sequence		P	P	G	T	E	G	D	I	G	I	R	V	K	P	I	R	P	I	G	I	F	S	G	Y	V	D	N	P	D	K	T	A	A	N	I	R	G	D	F	W	L	L	G	D	R	G	I	K	D	E	D	G	Y	F	Q	F	M	G	R	A	D	D	I	I	N	S	S	G	Y	R	I	G	P	S	E	V	E	N	A	L
Template Known Secondary structure			T	T										S	S	B			T	T	S					T	T								T			T	T												T	T	S								G	G	G					T	T
Template Predicted Secondary structure
Template SS confidence
		403	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.
		475	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.							510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.
Predicted Secondary structure																																					.	.	.	.	.	.
Query SS confidence																																					.	.	.	.	.	.
Query Sequence		M	Q	H	P	G	V	Q	E	V	A	A	V	G	V	P	S	G	S	S	G	E	A	V	K	I	F	V	V	K	K	D	P	S	L	T	.	.	.	.	.	.	E	E	S	L	V	T	F	C	R	R	Q	L	T	G	Y	K	V	P	K	L	V	E	F	R	D	E	L	P	K	S	N	V	G	K	I	L	R	R	E
Query Conservation																																					.	.	.	.	.	.
Alig confidence																																					.	.	.	.	.	.
Template Conservation
Template Sequence		M	E	H	P	A	V	V	E	T	A	V	I	S	S	P	D	P	V	R	G	E	V	V	K	A	F	V	V	L	A	S	Q	F	L	S	H	D	P	E	Q	L	T	K	E	L	Q	Q	H	V	K	S	V	T	A	P	Y	K	Y	P	R	K	I	E	F	V	L	N	L	P	K	T	V	T	G	K	I	Q	R	A	K
Template Known Secondary structure			T	S	T	T												T	T	T												G	G	G	G	G	S																	S		G	G	G	S		S						S				B		T	T			B
Template Predicted Secondary structure
Template SS confidence
		483	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.
		549	550	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	R	D	E	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	R	D	K	E
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		563	.	.	.	.