Job Description P27294 Confidence 99.64% Date Wed Jan 25 15:20:46 GMT 2012 Rank 188 Aligned Residues 154 % Identity 16% Template c3k54A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases. Resolution 1.94 Å

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		10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.		40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.
Predicted Secondary structure																																.
Query SS confidence																																.
Query Sequence		F	N	H	W	W	A	T	E	G	D	W	V	E	E	P	N	Y	R	R	N	G	M	S	G	V	Q	C	V	E	R	.	N	G	K	K	L	Y	V	K	R	M	T	H	H	L	F	H	S	V	R	Y	P	F	G	R	P	T	I	V	R	E	V	A	V	I	K	E	L	E	R	A	G	V	I	V	P	K	I	V	F
Query Conservation																																.
Alig confidence																																.												.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Y	G	S	W	E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	G	Q	Y	D	V	A	I	K	M	I	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	F	I	E	E	A	K	V	M	M	N	L	S	H	E	K	L	V	Q	L	Y	G	V	C
Template Known Secondary structure			G	G	G	B			G	G	G									S	T	T	S	S								T	T	T										.	.	.	.	.	.	.	.	.	.	.	.	.	.			T	T											T	T	B
Template Predicted Secondary structure																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		392	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.															.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.
		89	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	E	A	V	K	I	E	G	E	W	R	A	L	L	V	T	E	D	M	A	G	F	I	S	I	A	D	W	Y	A	Q	H	A	V	S	P	Y	S	D	E	V	R	Q	A	M	L	K	A	V	A	L	A	F	K	K	M	H	S	I	N	R	Q	H	G	C	C	Y	V	R	H	I	Y	V	K	T	E	G	N	A	E
Query Conservation
Alig confidence								.	.	.	.	.	.																							.	.																																											.	.
Template Conservation								.	.	.	.	.	.																							.	.																																											.	.
Template Sequence		T	K	Q	R	P	I	.	.	.	.	.	.	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	R	H	R	.	.	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	.	.
Template Known Secondary structure			S	S	S	S		.	.	.	.	.	.								T	T										G	G	G		.	.																							T	T				S			S	G	G	G					T	T			.	.
Template Predicted Secondary structure								.	.	.	.	.	.																							.	.																																											.	.
Template SS confidence
		465	.	.	.	.	470							.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.			.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.
		169	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	G	F	L	D	L	E	K	S	R	R	R	L	R	R	D	K	A	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	K	V	S	D	F	G	F	P	V	R	W	S	P	P	E	V	L	M
Template Known Secondary structure											G	G	G
Template Predicted Secondary structure
Template SS confidence
		535	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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