|   |
26 | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | T | E | D | E | S | K | E | K | Y | Y | C | L | S | M | L | P | Y | P | S | G | R | L | H | M | G | H | V | R | N | Y | T | I | G | D | V | I | A | R | Y | Q | R | M | L | G | K | N | V | L | Q | P | I | G | W | D | A | F | G | L | P | A | E | G | A | A | V | K | N | N | T | A | P | A | P | W | T | Y | D | N | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|
|
|   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| . |
|   |
|   |
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|
|
|   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
F | K | P | I | E | S | G | K | V | K | L | Y | V | C | G | X | T | . |
V | Y | D | Y | X | H | I | G | H | G | R | S | W | I | I | F | D | X | V | V | R | Y | L | R | X | R | G | Y | E | V | T | F | V | R | N | I | T | D | I | D | D | K | I | I | K | R | A | G | E | N | K | E | S | P | A | A | L | A | E | R | F | I |
Template Known Secondary structure |   |
|
|
| S | S | T | T |  |  |  |  |  |  |
|
|
| B | . | T | T | S |
|
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
| B | B |
|
|
|  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
16 | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | |
. | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . |
  |
  |   |
106 | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Y | M | K | N | Q | L | K | M | L | G | F | G | Y | D | W | S | R | E | L | A | T | C | T | P | E | Y | Y | R | W | E | Q | K | F | F | T | E | L | Y | K | K | G | L | V | Y | K | K | T | S | A | V | N | W | C | P | N | D | Q | T | V | L | A | N | E | Q | V | I | D | G | C | C | W | R | C | D | T | K | V | E | R |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |
|
|   |   |   |
|
|   |   |   |
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|
|   |
|   |   |   |
|   |
|   |
|   |   |   |
|   |
|
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|   |   |
| . | . |   |   |   |   |   |   |   |
| . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | I | L | H | E | D | E | K | A | L | R | V | L | S | P | . |
. |
D | Q | E | P | R | A | T | Q | . |
Y | V | P | E | I | I | K | L | I | Q | K | L | L | D | N | Q | Y | A | Y | T | G | Q | N | G | D | V | F | F | D | V | R | R | . |
. |
. |
. |
. |
. |
. |
. |
F | K | D | Y | G | K | L | S | H | R | H | L | D | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T |
|
|
|
| . | . | S | B |
|
| B | G | G | G | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |  |
| T | T | S |
|  |  |  |
| T | T | T | . | . | . | . | . | . | . | . |
| T | T | T | T | T | T | T | T |
| S |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|  |  |  |  |
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|  |  |  | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
95 | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | |
|
110 | . | . | . | . | . | . | . | |
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
186 | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | E | I | P | Q | W | F | I | K | I | T | A | Y | A | D | E | L | L | N | D | L | D | K | L | D | H | W | P | D | T | V | K | T | M | Q | R | N | W | I | G | R | S | E | G | V | E | I | T | F | N | V | N | D | Y | D | N | T | L | T | V | Y | T | T | R | P | D | T | F | M | G | C | T | Y | L | A | V | A | A | G | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|
|   |   |   |   |   |
|   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
K | R | D | P | L | D | F | V | L | W | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
| S | S | T | T |
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
176 | . | . | . | 180 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | L | A | Q | K | A | A | E | N | N | P | E | L | A | A | F | I | D | E | C | R | N | T | K | V | A | E | A | E | M | A | T | M | E | K | K | G | V | D | T | G | F | K | A | V | H | P | L | T | G | E | E | I | P | V | W | A | A | N | F | V | L | M | E | Y | G | T | G | A | V | M | A | V | P | G | H | D | Q | R | D |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |
|
|
|
|
|   |   |   |
|
|
|
|   |   |
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
346 | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | E | F | A | S | K | Y | G | L | N | I | K | P | V | I | L | A | A | D | G | S | E | P | D | L | S | Q | Q | A | L | T | E | K | G | V | L | F | N | S | G | E | F | N | G | L | D | H | E | A | A | F | N | A | I | A | D | K | L | T | A | M | G | V | G | E | R | K | V | N | Y | R | L | R | D | W | G | V | S | R | Q |
Query Conservation |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | A | K | P | G | E | P | K | W | D |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
| T | T | S |
|
| B |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
187 | . | . | 190 | . | . | . | . | . | . |
  |
  |   |
426 | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | Y | W | G | A | P | I | P | M | V | T | L | E | D | G | T | V | M | P | T | P | D | D | Q | L | P | V | I | L | P | E | D | V | V | M | D | G | I | T | S | P | I | K | A | D | P | E | W | A | K | T | T | V | N | G | M | P | A | L | R | E | T | D | T | F | D | T | F | M | E | S | S | W | Y | Y | A | R | Y | T | C |
Query Conservation |   |
|   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
S | P | W | G | E | G | R | P | G | W | H | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
| T | T |
| S |  |  |  |
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
197 | . | . | 200 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
506 | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | Q | Y | K | E | G | M | L | D | S | E | A | A | N | Y | W | L | P | V | D | I | Y | I | G | G | I | E | H | A | I | M | H | L | L | Y | F | R | F | F | H | K | L | M | R | D | A | G | M | V | N | S | D | E | P | A | K | Q | L | L | C | Q | G | M | V | L | A | D | A | F | Y | Y | V | G | E | N | G | E | R | N | W |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |   |   |
|   |   |   | . | . |   |   |
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
E | C | S | A | X | S | S | S | I | L | G | Q | P | F | D | I | H | G | G | G | L | D | L | K | F | P | H | H | E | N | . |
. |
E | I | A | Q | S | E | A | G | E | E | . |
. |
. |
. |
K | P | F | V | K | L | W | X | H | A | G | L | L | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  | G | G | G | T | T | T |  |  |  |  | . | . |  |  |  |  |  |  |  |  |  | S | . | . | . | . | S |
|
|  |  |  |  |  |  |  |
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  | . | . |  |  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
209 | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
|
. | 240 | . | . | . | . | . | . | . | . | |
|
|
|
. | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
586 | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | S | P | V | D | A | I | V | E | R | D | E | K | G | R | I | V | K | A | K | D | A | A | G | H | E | L | V | Y | T | G | M | S | K | M | S | K | S | K | N | N | G | I | D | P | Q | V | M | V | E | R | Y | G | A | D | T | V | R | L | F | M | M | F | A | S | P | A | D | M | T | L | E | W | Q | E | S | G | V | E | G |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |
|
|
|
|   |
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |
|
|
|
|
|   |
|   |   |
|   |   |   |
|
|
|
|   |   |   |   |
|
|
|
|
|   |
|
|   |   |   | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | N | K | E | K | X | S | K | S | L | G | N | I | I | S | I | R | E | A | L | K | E | S | D | V | E | V | L | R | Y | F | L | L | S | G | H | . |
Y | R | N | P | L | S | Y | S | K | E | N | L | E | N |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  | T | T |  |  |
|
| T | T | T | T |
|
|
| B |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  | S |
| . | T | T | S |
|  |  |  |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | |
. | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
  |
  |   |
666 | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | N | R | F | L | K | R | V | W | K | L | V | Y | E | H | T | A | K | G | D | V | A | A | L | N | V | D | A | L | T | E | N | Q | K | A | L | R | R | D | V | H | K | T | I | A | K | V | T | D | D | I | G | R | R | Q | T | F | N | T | A | I | A | A | I | M | E | L | M | N | K | L | A | K | A | P | T | D | G | E | Q |
Query Conservation |   |
  |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
G | R | L | A | L | E | R | F | Y | L | A | L | R | G | L | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | S | S | Y | T | D | R | F | Y | E | A | X | D | D | D | F | N | T | P | I | A | F | A | L | L | F | E | X | V | R | E | I | N | R | F | R | D | N | N | Q | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  | T | B | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . |
  |
  |   |
746 | . | . | . | 750 | . | . | . | |
. | . | . | . | . | . | 760 | . | . | |
|
. | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
Query Sequence |   |
D | R | A | L | M | Q | E | A | . |
L | L | A | V | V | R | M | L | N | . |
. |
P | F | T | P | H |
Query Conservation |   |
  |   |   |   |
|   |   |   | . |
|   |   |
|   |   |
|
|
| . | . |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |
Template Sequence |   |
E | K | A | A | V | L | A | A | E | L | K | C | L | G | N | I | F | G | L | L | Q | Y | S | P | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | T |
| S |
| S |
|  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
376 | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 |
  |